BioRepository Core

生物样本库核心

• 批准号: 9335470
• 负责人: Marcelo Fernandez-Vina
• 金额: $ 8.15万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9335470
• 关键词: Aliquot; Automobile Driving; Basic Science; Bioinformatics; Biological; Biological Specimen Banks; Code; DNA; DNA Repository; Future; Genetic; Genetic study; Genotype; Goals; Human Resources; Immunogenetics; Laboratories; Multiple Sclerosis; Neurology; Procedures; Research Infrastructure; Research Personnel; Resources; Sampling; Secure; Services; Specimen; Standardization; Testing; Translational Research; biobank; disorder risk; experience; nervous system disorder; next generation sequencing; programs; sample collection

Biological sample collection, processing, storage, and distribution are essential components of large collaborative genetic studies. The overall objective of the BioRepository Core is to maintain a readily accessible biological specimens bank in support of the projects within this application. The Core services will be provided by the lab facilities located within the Multiple Sclerosis Genetics Program at the Department of Neurology, UCSF. With over two decades of experience, the MS Bio-Bank has both the expertise and infrastructure to serve as an efficient and reliable component of the INDIGO program. In addition to centralizing the management of DNA specimens arriving from different laboratories, the main goal of the Core is to provide standardized samples to the genotyping effort proposed in this application. The Core is well equipped and staffed by experienced personnel. Established standard operating procedures and efficient bioinformatic support will serve the programmatic needs of the INDIGO consortium and secure a valuable resource for future basic and translational research.

生物样品收集，加工，存储和分布是大的重要组成部分 协作遗传学研究。生物座位核心的总体目标是保持轻松 可访问的生物标本库支持本应用程序中的项目。核心服务将 由位于部门的多发性硬化症遗传学计划中的实验室设施提供 神经病学，UCSF。拥有二十年的经验，MS Bio-Bank既有专业知识，又有 基础架构是Indigo计划的有效且可靠的组成部分。 除了集中从不同实验室到达的DNA标本的管理外，主要的 核心的目标是为本应用程序中提出的基因分型工作提供标准化样本。这 核心设备齐全，由经验丰富的人员配备。已建立的标准操作程序 有效的生物信息学支持将满足靛蓝财团的程序需求，并确保 未来基础和翻译研究的宝贵资源。