Chemistry and Biology Interface (CBI) NIH T32 Training Grant

化学与生物接口 (CBI) NIH T32 培训补助金

• 批准号: 9793543
• 负责人: BRIAN J BAHNSON
• 金额: $ 38.13万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9793543
• 关键词: Biology; Chemistry; Grant; Training; United States National Institutes of Health

The objective of this Chemistry-Biology Interface (CBI) Predoctoral Program is to provide cross-disciplinary training to talented students with diverse interests that will enable them to apply the mechanistic and atomistic perspective of chemistry to important biological problems. The program brings together 42 faculty trainers from eight academic units at the Univ. of Delaware representing disciplines of organic chemistry, analytical chemistry, biochemistry, chemical biology, structural biology, molecular biology, cell biology, systems biology, bioinformatics, molecular biology, cell biology, microbiology, virology, and developmental biology. The faculty trainers include both new and established researchers with vibrant research programs in biomolecular science and experience in training graduate students. A diverse trainee group (with a focus to recruit and retain URMs) with varied educational backgrounds are selected on the basis of their desire to explore multidisciplinary problems at the interface of chemistry and biology, their GRE scores, undergraduate GPA, letters of recommendation and research background. Eight trainees are admitted each year through existing graduate programs of Chemistry & Biochemistry, Chemical & Biomolecular Engineering, Biological Sciences or other CBI trainer departments and university supported for their first year. A second, funded track of admission to the CBI program is outlined; students with a strong interest in research at the interface of chemistry and biology will be invited to apply at the end of their first or second year of their graduate studies. All trainees will satisfy the degree requirements for their specific departmental program in addition to the requirements for the CBI program. Three one semester courses will be selected from a diverse list of course offerings from six departments. A key feature of the CBI program is the laboratory rotations each trainee undertakes to provide them with hands-on experience in the different disciplines. Between courses and laboratory rotations students are expected to have exposure to concepts and methods from the atomistic to the cellular. Students are empowered by this background to think creatively about biological and chemical problems that are relevant to human health. This proposal aims to provide students with a menu of university funded internships (local pharmaceutical/biotech firms, National Labs and new collaborations to enhance their career development. All trainees are required to participate in a series of quarterly responsible conduct of research (RCR) workshops, a 2-day University sponsored RCR and a January workshop of data reproducibility and rigor. A weekly seminar series brings the CBI community together and provides trainees numerous opportunities to present their own work, as well as learn from both faculty trainers and outside speakers. Each trainee undertakes an intensive independent research experience culminating in a dissertation representing an original contribution to a field at the chemistry-biology interface. This program follows and builds on a successful 25-year model for training scientists with both broad scientific knowledge as well as solid foundations in a chosen core discipline.

该化学生物学界面（CBI）的目的是提供跨学科 培训有多种兴趣的才华横溢的学生，这将使他们能够运用机械和原子化 重要生物学问题的化学观点。该计划汇集了42位来自 大学的八个学术单位。特拉华州代表有机化学学科的分析学科 化学，生物化学，化学生物学，结构生物学，分子生物学，细胞生物学，系统生物学， 生物信息学，分子生物学，细胞生物学，微生物学，病毒学和发育生物学。教师 培训师包括新的和已成熟的研究人员，具有生物分子科学的充满活力的研究计划 和培训研究生的经验。一个多元化的学员小组（重点是招募和保留URMS） 根据他们希望探索多学科的愿望，选择了各种教育背景 化学与生物学界面的问题，他们的GRE分数，本科GPA，字母 建议和研究背景。每年通过现有研究生录取八名学员 化学与生物化学，化学与生物分子工程，生物科学或其他计划 CBI培训师部门和大学为第一年提供了支持。第二次资助的入学曲目 CBI计划概述了；在化学和生物学界面上对研究感兴趣的学生 将邀请他们在研究生学习的第一年或第二年结束时申请。所有学员都会满足 除了CBI的要求外，其特定部门计划的学位要求 程序。三个学期课程将从六个课程的各种列表中选出 部门。 CBI计划的一个关键特征是每个学员承诺提供的实验室轮换 他们在不同学科的动手经验中。课程和实验室轮换学生之间 预计将暴露于原子体到细胞的概念和方法。学生是 赋予这种背景的能力，以创造性地思考与 人类健康。该建议旨在为学生提供大学资助的实习菜单（本地 制药/生​​物技术公司，国家实验室和新的合作，以增强其职业发展。全部 学员必须参加一系列季度负责任的研究（RCR）讲习班， 2天大学赞助了RCR和一月份的数据可重复性和严格性研讨会。每周研讨会 系列将CBI社区汇集在一起​​，并为受训者提供了许多机会来展示自己的 工作，以及向教职员工和外部演讲者学习。每个实习生都进行了密集的 独立的研究经验最终在论文中代表对领域的原始贡献 化学生物学界面。该计划遵循并建立在成功的25年培训模型上 具有广泛科学知识的科学家以及所选核心纪律中的坚实基础。