Chemistry and Biology Interface (CBI) NIH T32 Training Grant

化学与生物接口 (CBI) NIH T32 培训补助金

• 批准号: 10610185
• 负责人: BRIAN J BAHNSON
• 金额: $ 8.64万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10610185
• 关键词: Biology; Chemistry; Grant; Training; United States National Institutes of Health; Biology; Chemistry; Grant; Training; United States National Institutes of Health

CBI T32 Abstract: The objective of this Chemistry-Biology Interface (CBI) Predoctoral Program is to provide cross-disciplinary training to talented students with diverse interests that will enable them to apply the mechanistic and atomistic perspective of chemistry to important biological problems. The program brings together 42 faculty trainers from eight academic units at the Univ. of Delaware representing disciplines of organic chemistry, analytical chemistry, biochemistry, chemical biology, structural biology, molecular biology, cell biology, systems biology, bioinformatics, molecular biology, cell biology, microbiology, virology, and developmental biology. The faculty trainers include both new and established researchers with vibrant research programs in biomolecular science and experience in training graduate students. A diverse trainee group (with a focus to recruit and retain URMs) with varied educational backgrounds are selected on the basis of their desire to explore multidisciplinary problems at the interface of chemistry and biology, their GRE scores, undergraduate GPA, letters of recommendation and research background. Eight trainees are admitted each year through existing graduate programs of Chemistry & Biochemistry, Chemical & Biomolecular Engineering, Biological Sciences or other CBI trainer departments and university supported for their first year. A second, funded track of admission to the CBI program is outlined; students with a strong interest in research at the interface of chemistry and biology will be invited to apply at the end of their first or second year of their graduate studies. All trainees will satisfy the degree requirements for their specific departmental program in addition to the requirements for the CBI program. Three one semester courses will be selected from a diverse list of course offerings from six departments. A key feature of the CBI program is the laboratory rotations each trainee undertakes to provide them with hands- on experience in the different disciplines. Between courses and laboratory rotations students are expected to have exposure to concepts and methods from the atomistic to the cellular. Students are empowered by this background to think creatively about biological and chemical problems that are relevant to human health. This proposal aims to provide students with a menu of university funded internships (local pharmaceutical/biotech firms, National Labs and new collaborations to enhance their career development. All trainees are required to participate in a series of quarterly responsible conduct of research (RCR) workshops, a 2-day University sponsored RCR and a January workshop of data reproducibility and rigor. A weekly seminar series brings the CBI community together and provides trainees numerous opportunities to present their own work, as well as learn from both faculty trainers and outside speakers. Each trainee undertakes an intensive independent research experience culminating in a dissertation representing an original contribution to a field at the chemistry-biology interface. This program follows and builds on a successful 25-year model for training scientists with both broad scientific knowledge as well as solid foundations in a chosen core discipline. With this Mentoring Supplement, we aim to broaden our efforts in mentor training with a focus on culturally aware mentoring and create an environment where supportive mentoring is championed.

CBI T32摘要：该化学生物学界面（CBI）的目的 是为具有多种兴趣的才华横溢的学生提供跨学科培训，这将使 他们将化学的机械和原子观点应用于重要的生物学 问题。该计划汇集了来自大学八个学术单位的42名教师培训师。 特拉华州代表有机化学学科，分析化学，生物化学， 化学生物学，结构生物学，分子生物学，细胞生物学，系统生物学， 生物信息学，分子生物学，细胞生物学，微生物学，病毒学和发育生物学。 教师培训师包括具有充满活力的研究计划的新研究人员和知名的研究人员 在生物分子科学和培训研究生方面的经验。一个多元化的学员小组 （以招募和保留URM的重点）选择了具有多种教育背景的 他们渴望在化学界面探索多学科问题的愿望和 生物学，他们的GRE分数，本科GPA，推荐信和研究信 背景。每年通过现有的研究生课程入院 化学与生物化学，化学与生物分子工程，生物科学或其他 CBI培训师部门和大学为第一年提供了支持。第二个资助的轨道 概述了CBI计划的入学；对研究有浓厚兴趣的学生 化学和生物学的界面将邀请在其第一年或第二年结束时申请 他们的研究生学习。所有学员将满足其特定学位要求 除了CBI计划的要求外，部门计划。三个学期 课程将从六个部门的课程供应列表中选出。一个关键功能 CBI计划的是每个学员承诺的实验室旋转 在不同学科的经验。课程和实验室轮换之间的学生是 预计将暴露于原子体到细胞的概念和方法。学生 通过这种背景授权，可以创造性地思考生物学和化学问题 与人类健康有关的。该建议旨在为学生提供大学菜单 资助实习（当地的药物/生物技术公司，国家实验室和新合作 增强他们的职业发展。所有学员都必须参加一系列季度 负责任的研究（RCR）讲习班，为期2天的大学赞助RCR和A 一月份的数据可重复性和严谨性。每周一次的研讨会系列带来了CBI 共同社区，为受训者提供了许多机会展示自己的工作，因为 以及向教职员工和外部演讲者学习。每个实习生承担 密集的独立研究经验最终在代表原始的论文中最终 对化学生物学界面的领域的贡献。该程序遵循并建立在 具有广泛科学知识的培训科学家的成功25年模型以及 在选定的核心学科中的固体基础。通过这种指导补充，我们旨在扩大 我们在指导培训方面的努力，重点是文化意识和创造环境 支持指导的地方。