BIOSTATISTICS SHARED RESOURCE

生物统计共享资源

• 批准号: 8340108
• 负责人: MOTOMI MORI
• 金额: $ 10.11万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-20 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340108
• 关键词: Address; Adopted; Applications Grants; Award; Back; Basic Science; Biometry; Biostatistics Shared Resource; Budgets; Cancer Biology; Cancer Center; Cancer Center Support Grant; Cancer Research Project; Categories; Charge; Clinical Protocols; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Concept Formation; Consult; Consultations; Data; Data Analyses; Development; Education; Educational workshop; Environment; Epidemiology; Etiology; Experimental Designs; Funding; Genetic; Genomics; Goals; Grant; Health; Hour; Individual; Institutes; Institution; Instruction; Journals; K-Series Research Career Programs; Knowledge; Laboratories; Malignant Neoplasms; Manuscripts; Medical center; Mentors; Monitor; Pilot Projects; Play; Population Sciences; Preparation; Prevention; Proteomics Shared Resource; Protocols documentation; Public Health; Publications; Publishing; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Review Committee; Role; Safety; Sample Size; Staging; System; Training; Training Activity; Training and Education; Triage; United States National Institutes of Health; anticancer research; cost effective; data management; meetings; member; new technology; operation; programs

The Biostatistics Shared Resource (BSR) of the Knight Cancer Institute (Knight) is a cancer-center managed shared resource and provides biostatistics support to basic, clinical and population science researchers who conduct cancer research at OHSU and partner institutions (e.g., Portland VA Medical Center, Kaiser Permanente Center for Health Research). In addition to providing support to individual researchers, the BSR also assists other Knight shared resources in addressing their biostatistics needs. The BSR strives to enhance the scientific quality and statistical sophistication of cancer research through tailored professional consultation at every level and stage of cancer research. By leveraging CCSG support, the Knight institutional commitment, and other cancer specific grant support, the BSR provides a wide range of biostatistics expertise and supports cancer researchers in a cost-effective manner. Support activities are divided into four major categories: (1) pre-award support, (2) post-award support, (3) infrastructure support, and (4) education and training. Pre-award support includes consultation on study and experimental designs, sample size and power analysis, and statistical analysis plan for investigator-initiated clinical protocols and grant proposals. Post-award support includes protocol implementation, data management, statistical analysis, and manuscript preparation. Infrastructure support refers to collaborative projects with other shared resources to enhance the overall research infrastructure, including development and implementation of statistical protocols for high-throughput genetics/genomics studies, clinical research support through participation in the Protocol Review and Monitorihg^System (i.e., Clinical Research Review Committee and Data and Safety Monitoring Committee). Education and training activities include participation in various cancer journal clubs, research-in-progress meetings, short-term biostatistics workshops, didactic courses in clinical trials and statistical genetics, and professional development activities for BSR members. The BSR is highly utilized and has contributed significantly to cancer research conducted at the Knight. In 2009 the BSR assisted a total of 129 projects from 55 investigators from all four research programs, provided a total of 2,562 consulting hours for investigator-support activities. Between 2005 and 2010, the BSR assisted 65 cancer relevant publications (65 published, 9 in press, revision or submitted). The BSR emphasizes research collaboration at the earliest stage possible as most productive research is conducted under a collaborative research environment

骑士癌症研究所（Knight）的生物统计学共享资源（BSR）是一种癌症中心的管理 共享资源并为在OHSU和合作伙伴机构（例如，Kaiser Permanente Health Research Center的Portland VA医疗中心）进行癌症研究的基础，临床和人口科学研究人员提供生物统计学支持。除了为个别研究人员提供支持外，BSR还协助其他骑士共享资源，以满足其生物统计学需求。 BSR努力 通过在癌症研究的各个级别和阶段量身定制的专业咨询来增强癌症研究的科学质量和统计学成熟。通过利用CCSG支持，骑士机构的承诺以及其他特定于癌症的赠款支持，BSR提供了广泛的生物统计学专业知识，并以具有成本效益的方式为癌症研究人员提供支持。支持活动分为四个主要类别：（1）雄辩前的支持，（2）雄辩后的支持，（3）基础设施支持以及（4）教育和培训。预先支持的支持包括有关研究和实验设计的咨询，样本量和功率分析以及研究人员发起的临床方案的统计分析计划和批准建议。奖后的支持包括协议实施，数据管理，统计分析和手稿准备。基础设施支持是指与其他共享资源的合作项目，以增强整体研究基础设施，包括开发和实施高通量遗传学/基因组学研究的统计协议，通过参与协议审查和MonerationIhg^系统（即临床研究审查委员会以及数据审查委员会以及数据和数据监测委员会），临床研究支持。教育和培训活动包括参与各种 癌症杂志俱乐部，进行研究的会议，短期生物统计学研讨会，临床试验和统计遗传学的教学课程以及BSR成员的专业发展活动。 BSR高度使用，并为在骑士进行的癌症研究做出了重大贡献。 2009年，BSR协助了来自所有四项研究计划的55名调查人员的129个项目，总共提供了 2,562个咨询时间用于调查员 - 支持活动。在2005年至2010年之间，BSR协助了65个癌症相关出版物（65份出版，新闻，修订或提交）。 BSR在最早的阶段强调研究合作，因为大多数富有成效的研究是在协作研究环境下进行的