The effect of e-cigarette and hookah use on the age of asthma onset in the USA

使用电子烟和水烟对美国哮喘发病年龄的影响

• 批准号: 10704075
• 负责人: Adriana Perez
• 金额: $ 19.5万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10704075
• 关键词: Address; Adult; Age; Area; Asthma; Behavioral; Cigarette; Complex; Data; Disease; Early Diagnosis; Economics; Electronic cigarette; Epidemiology; Etiology; General Population; Health; Health Personnel; Knowledge; Long-Term Effects; Outcome; Patients; Persons; Physicians; Population Assessment of Tobacco and Health; Public Health; Research; Research Priority; Risk; Risk Factors; Sampling; Testing; Tobacco; Tobacco use; United States; United States Food and Drug Administration; Youth; cigarette smoking; cigarette user; electronic cigarette use; hookah; innovation; interest; non-cigarette tobacco product; novel; prevent; prospective; screening; tobacco products

PROJECT SUMMARY Innovative analysis of existing behavioral data to study the etiology and epidemiology of the age of asthma onset among past 30-day e-cigarette and hookah users is responsive to the scientific interest area on health effects by understanding the short and long-term effects of these tobacco products in the U.S. This proposal focuses on the age of asthma onset in youth and adults. E-cigarettes and hookah are now dominant features of the current tobacco marketplace, and they have the potential to harm the health of users in ways similar to cigarettes. Therefore, estimating the age of asthma onset to evaluate the effect of past 30-day e-cigarette and hookah use among never cigarette users is paramount to protect public health, educate the public, and provide evidence to the Food and Drug Administration (FDA). Information on an earlier age of asthma onset will quantify and display the potential risk of these tobacco products, which can help prevent people from initiating use or motivate users to quit. In addition, the most effective way to control and treat asthma is with early detection of the disease. Providing information on the age of asthma onset in e-cigarette and hookah users can help provide necessary information to physicians and health care providers on the appropriate age windows for asthma screening in patients who use these tobacco products. We propose to estimate the age asthma of onset using waves 1-5 (and any subsequent waves released during our study period) of the Population Assessment of Tobacco and Health (PATH) Study. Two aims are proposed: Aim 1: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between e-cigarette use and the age of asthma onset after controlling for other risk factors. Aim 2: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between hookah use and the age of asthma onset after controlling for other risk factors. Analyses for Aims 1 and 2 will be conducted among never cigarette users to avoid potential confounding from cigarette use. There is a gap in the knowledge related to the age of asthma onset, specifically among e-cigarette and hookah users. The most effective way to establish these associations is with longitudinal, prospective research. Few studies can test hypotheses with longitudinal data on tobacco-related health outcomes, including asthma that is nationally representative of U.S. youth and adults. This project addresses a critical need to understand and guide efforts to provide FDA, the Center for Tobacco Products, and the general public with more information on the effects of using these tobacco products to reduce their public health toll in the United States.

项目概要 创新分析现有行为数据，研究年龄增长的病因学和流行病学 过去 30 天电子烟和水烟使用者的哮喘发作符合科学兴趣 通过了解这些烟草制品对健康影响的短期和长期影响 美国这项提案的重点是青少年和成人哮喘的发病年龄。电子烟和 水烟现在是当前烟草市场的主导特征，并且它们有潜力 以类似于香烟的方式损害使用者的健康。因此，估计哮喘发病年龄 评估过去 30 天电子烟和水烟使用对从不吸烟者的影响 对于保护公众健康、教育公众以及向食品和药品管理局提供证据至关重要 管理（FDA）。有关哮喘发病较早年龄的信息将量化并显示 这些烟草产品的潜在风险，这可以帮助防止人们开始使用或激励 用户退出。此外，控制和治疗哮喘最有效的方法是及早发现 这种疾病。提供有关电子烟和水烟使用者哮喘发病年龄的信息可以 帮助向医生和医疗保健提供者提供有关适当年龄的必要信息 对使用这些烟草产品的患者进行哮喘筛查的窗口。我们建议估计 使用第 1-5 波（以及我们研究期间释放的任何后续波）的发病年龄哮喘 人口烟草与健康评估 (PATH) 研究的期间）。提出了两个目标： 目标 1：估计 12-75 岁以上青少年和成人哮喘发病年龄，以及 控制电子烟使用与哮喘发病年龄之间的关系 其他风险因素。目标 2：估计 12-75 岁以上青少年和成人哮喘发病年龄 岁，并探讨水烟使用与哮喘发病年龄之间的关系 控制其他风险因素。目标 1 和 2 的分析将在从不吸烟的人群中进行 用户避免因吸烟而造成潜在的混淆。相关知识存在差距 哮喘发病年龄，特别是电子烟和水烟使用者。最有效的方法是 建立这些关联是通过纵向、前瞻性研究。很少有研究可以测试 假设与烟草相关的健康结果的纵向数据，包括哮喘 美国青年和成年人的全国代表。该项目解决了一个关键需求 了解并指导向 FDA、烟草制品中心和一般公众提供服务的努力 向公众提供有关使用这些烟草产品的影响的更多信息，以减少公众的注意力 美国的健康损失。