Age of Initiation of Tobacco Products among USA Youth and Young Adults: Administrative Supplement

美国青少年开始使用烟草制品的年龄：行政补充

• 批准号: 10159592
• 负责人: Adriana Perez
• 金额: $ 9.7万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-04 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10159592
• 关键词: 17 year old; Address; Administrative Supplement; Age; Age Distribution; Age of Onset; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Area; Back; Behavior; Cessation of life; Cigar; Cigarette; Communication; Consumption; Data; Data Analyses; Disease; Electronic cigarette; Funding; Future; Generations; Health Knowledge, Attitudes, Practice; Individual; Institutes; Light; Longitudinal Studies; Malignant Neoplasms; Measures; Mental Health; Outcome; Participant; Pattern; Population Assessment of Tobacco and Health; Prevalence; Prevention; Public Health; Recommendation; Regulation; Relapse; Reporting; Research; Research Priority; Risk; Risk Factors; Sampling; Smokeless Tobacco; Survival Analysis; Time; Tobacco; Tobacco use; Youth; alcohol content; bidis; binge drinking; boys; cancer risk; cigarette smoking; cigarette user; cigarillos; electronic cigarette use; girls; hookah; improved; innovation; interest; parent grant; parent project; prevent; prospective; response; secondary analysis; smokeless tobacco use; snus; sociodemographics; tobacco control; tobacco products; tobacco user; young adult

PROJECT SUMMARY This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA- 20-039. This project directly addresses the research priority areas that focus on understanding the knowledge, attitudes, and behaviors that contribute to the age of initiation of co-use of multiple tobacco products (TP) and binge drinking in youth, and their associated factors. Given the tobacco product combinations that are most prevalent among youth, this project focuses on (i) cigarettes, e-cigarettes (c-ecig) and binge drinking, and (ii) cigarettes, cigarillos (c-c) and binge drinking to improve public health outcomes and prevent disease, such as cancer. For the purposes of this proposal, co-use is defined as past 30-day use of all products, simultaneously, in the same wave in the Population Assessment of Tobacco and Health (PATH) study. Prospectively estimating the age of initiation, defined as first past 30-day report of multiple TP use and binge drinking among youth who reported never use of the three products at their first wave of participation is innovative given the research gap in what we know about their co-use. Our supplemental study is a prospective secondary analysis of the first four waves of PATH among U.S. youth (12-17 years old) who reported never use of cigarettes, e- cigarettes, cigarillos and binge drinking, at their first wave of participation in PATH. The parent grant has three aims. Aim 1: Among youth ages 12-17 years old who are never users of TPs at wave 1, to estimate prospectively their age of initiation of TPs and to identify the risk factors associated with the age of initiation of cigarettes and each one of the NCTPs: e-cigarettes, cigars, hookah, and smokeless tobacco. Aim 2: same as aim 1 but among young adults ages 18-24 years old who are never users of TPs at wave 1. Aim 3: Among youth and young adults ages 12-24 who are never users of TPs at wave 1, to identify the trajectories and transitions in the onset of TPs across time, from waves 1 to 4, and to identify the risk factors associated with these trajectories and transitions. This supplement adds Aim 4: Among youth ages 12-17 years old who are never users of these TPs and alcohol at their first wave of participation in PATH, to prospectively estimate their age of initiation (i.e., first report) of (i) past 30-day use of c-ecig and binge drinking, and (ii) past 30-day use of c-c and binge drinking, using survival analyses, and to identify the risk factors associated with their co-use. We plan to explore a variety of socio-demographic, interpersonal and intrapersonal factors with these outcomes. Few studies can estimate the age of initiation of co-use with longitudinal data that span youth and young adults. This includes tracking outcomes and their age of initiation of underage (i.e., youth) participants that become young adults in PATH. This project strengthens the evidence regarding co-use of multiple TPs and binge drinking using a national longitudinal study and takes advantage of contemporary data that reflects the evolving TP landscape. Also, the results are essential for tobacco control as recent studies indicate that the use of TPs with alcohol increases the amount of use of both and may explain future cancer risk and deaths.

项目概要 本申请是为了响应被识别为 NOT-CA- 的特殊利益通知 (NOSI) 而提交的 20-039。该项目直接解决了重点关注理解知识的研究优先领域， 导致开始同时使用多种烟草产品 (TP) 的态度和行为，以及 青少年酗酒及其相关因素。鉴于最常见的烟草产品组合 该项目在年轻人中普遍存在，重点关注 (i) 香烟、电子烟 (c-ecig) 和酗酒，以及 (ii) 香烟、小雪茄 (c-c) 和酗酒，以改善公共卫生结果并预防疾病，例如 癌症。就本提案而言，共同使用被定义为过去 30 天同时使用所有产品， 在同一波烟草与健康人口评估（PATH）研究中。前瞻性地 估计开始年龄，定义为过去 30 天首次报告多次使用 TP 和酗酒的人群 考虑到在第一波参与中从未使用过这三种产品的年轻人是创新的 我们对它们的共同使用了解的研究差距。我们的补充研究是前瞻性二次分析 在前四波 PATH 调查中，美国青少年（12-17 岁）报告称从未使用过香烟、电子烟 香烟、小雪茄和酗酒，这是他们第一次参与 PATH。家长补助金有三项 目标。目标 1：在第一波从未使用过 TP 的 12-17 岁青少年中进行估计 前瞻性地预测他们开始 TP 的年龄，并确定与开始 TP 年龄相关的风险因素 香烟和每一种 NCTP：电子烟、雪茄、水烟和无烟烟草。目标 2：与 目标 1，但针对从未使用过第 1 波 TP 的 18-24 岁年轻人。目标 3： 从未使用过第一波 TP 的 12-24 岁青年和年轻人，以确定轨迹并 TP 发作随时间的推移（从第 1 波到第 4 波）的转变，并确定与 这些轨迹和转变。本增刊增加了目标 4：在 12 至 17 岁的青少年中， 从未在第一次参加 PATH 时使用这些 TP 和酒精，以前瞻性地估计他们的 (i) 过去 30 天使用 c-ecig 和酗酒的开始年龄（即第一次报告），以及 (ii) 过去 30 天使用 c-c 和酗酒，使用生存分析，并确定与其共同使用相关的风险因素。我们 计划探索各种社会人口、人际关系和内心因素与这些结果的关系。 很少有研究能够利用跨越青年和年轻人的纵向数据来估计开始同居的年龄 成年人。这包括跟踪未成年（即青年）参与者的结果和他们的开始年龄 成为 PATH 中的年轻人。该项目加强了关于共同使用多个TP的证据 酗酒使用了一项全国纵向研究，并利用了反映酗酒情况的当代数据 不断变化的TP景观。此外，这些结果对于烟草控制也至关重要，因为最近的研究表明 将 TP 与酒精一起使用会增加两者的使用量，并可能解释未来的癌症风险和死亡。