HIV Vaccines

艾滋病毒疫苗

• 批准号: 7930431
• 负责人: ANDREW D ROBERTSON
• 金额: $ 1.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7930431
• 关键词: AIDS Vaccines; Acquired Immunodeficiency Syndrome; Address; Adenoviruses; Alberta province; Canada; Clinical Trials; Collaborations; Communities; Consensus; Development; Fertilization; Fostering; Future; HIV; HIV vaccine; Human; Immune response; Immune system; Immunity; Immunologist; Immunology; Infection; Joints; Lead; Pathogenesis; Prevention; Renaissance; Research Personnel; Science; Scientist; Vaccine Research; Vaccines; Viral; Virus Diseases; innovation; insight; meetings; novel; public health priorities; sobriety; symposium; vaccine candidate; vaccinology; ward

DESCRIPTION (provided by applicant): This proposal is to request support for a Keystone Symposia meeting entitled "HIV Vaccines", organized by Wayne C. Koff, Lynn Morris and Marcus Altfeld, which will be held in Banff, Alberta, Canada from March 21-26, 2010. Recent clinical trials, and in particular the STEP trial of Merck's adenovirus AIDS vaccine candidate, have produced results disappointing to the AIDS vaccine field generally, and have given rise to the sobering realization that the majority of vaccine candidates currently under development are unlikely to provide a truly effective AIDS vaccine. Hence there is now a broad consensus that the field needs to return to some fundamentals of immunology, and addressing how the human (and simian) immune system interacts with HIV and what will be required in an effective immune response against HIV to ward off establishment of infection. To stimulate new insights and approaches to these longstanding problems, Keystone Symposia is offering a novel conference format that facilitates a wider cross-fertilization of ideas among the wider HIV vaccine research community. To that end, the 2010 Keystone Symposia HIV Vaccines meeting will foster innovative ideas and new collaborations between immunology and vaccinology as it pertains to other viral diseases. Traditionally, Keystone Symposia has held concurrent meetings on HIV, integrating vaccines and pathogenesis discussions. For 2010, a new joint symposium of HIV Vaccines in conjunction with Viral Immunity will be convened. These concurrent symposia will greatly encourage cross-fertilization of ideas, allowing AIDS vaccine researchers to interact with viral immunologists who approach immunity from a more fundamental perspective.

描述（由申请人提供）：本提案旨在请求对题为“HIV 疫苗”的 Keystone 研讨会的支持，该会议由 Wayne C. Koff、Lynn Morris 和 Marcus Altfeld 组织，将于 3 月 21 日在加拿大艾伯塔省班夫举行2010年-26日。最近的临床试验，特别是默克公司的腺病毒艾滋病候选疫苗的STEP试验，其结果普遍令艾滋病疫苗领域感到失望，并引起了人们的关注。令人警醒的是，目前正在开发的大多数候选疫苗不太可能提供真正有效的艾滋病疫苗。因此，现在达成了广泛的共识，即该领域需要回归免疫学的一些基础知识，并解决人类（和猿猴）免疫系统如何与艾滋病毒相互作用，以及针对艾滋病毒的有效免疫反应需要什么，以防止艾滋病毒的建立。感染。为了激发对这些长期存在的问题的新见解和新方法，Keystone Symposia 提供了一种新颖的会议形式，以促进更广泛的艾滋病毒疫苗研究界之间更广泛的思想交叉交流。 为此，2010 年 Keystone HIV 疫苗研讨会将促进免疫学和疫苗学之间针对其他病毒性疾病的创新理念和新合作。传统上，Keystone Symposia 会同时举办有关艾滋病毒的会议，整合疫苗和发病机制的讨论。 2010年，将召开新的艾滋病毒疫苗与病毒免疫联合研讨会。这些同期举行的研讨会将极大地鼓励思想的交叉融合，使艾滋病疫苗研究人员能够与从更基本的角度研究免疫的病毒免疫学家进行互动。