An Implementation-Effectiveness Study of an Evidence-Based Intervention to Improve Head Impact Safety in Youth Football

改善青少年足球头部碰撞安全的循证干预措施的实施效果研究

• 批准号: 10679431
• 负责人: Madison Evelyn Marks
• 金额: $ 4.77万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-09 至 2025-03-08
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10679431
• 关键词: Active Learning; Age; Award; Biomechanics; Biometry; Brain; Brain Concussion; Brain Diseases; Brain Injuries; Certification; Clinical; Clinical Trials Design; Communities; Custom; Data; Data Collection; Development; Effectiveness; Effectiveness of Interventions; Elements; Enrollment; Environment; Evaluation; Evidence based intervention; Exposure to; Fellowship; Frequencies; Funding; Future; Goals; Injury; Intervention; Lead; Life; Manufactured football; Measures; Mentors; Mentorship; Methods; Minor; Monitor; Musculoskeletal Equilibrium; National Institute of Child Health and Human Development; Nerve Degeneration; Nervous System Physiology; Neurocognition; Neurocognitive; Neurologic Deficit; Neuropsychology; Outcome; Parents; Pathology; Pilot Projects; Positioning Attribute; Prevention strategy; Process; Productivity; Public Health; Research; Research Personnel; Safety; Scientist; Seasons; Severities; Sports; Sports Medicine; Structure; Testing; Time; Training; Traumatic Brain Injury; Work; Youth; acceptability and feasibility; clinical outcome assessment; clinical outcome measures; cognitive change; college; comparative; contact sports; data management; effectiveness evaluation; effectiveness/implementation study; experience; head impact; high school; human subject; implementation process; implementation science; implementation strategy; improved; inferential statistics; injury prevention; insight; instrument; intervention program; junior high school; meetings; motor symptom; neurocognitive test; novel; oculomotor; pre-doctoral; prevent; rate of change; recruit; sensor; skills; success; youth sports

PROJECT SUMMARY Repetitive head impacts in contact sports are a significant public health concern due to their potential association with short- and long-term neurological deficits. There is debate amongst researchers as to the amount of exposure that may lead to neurocognitive changes; some researchers have demonstrated that these alterations could occur over the span of one season. Youth football players represent 70% of all athletes participating in the sport and experience over half of their head impacts during practice - an environment amendable to intervention. A current study (1K25HD101686-01A1) will develop an evidence-based intervention aimed to reduce head impact exposure in practices, using a community-engaged approach. This proposal enhances this parent study by incorporating clinical outcome assessments and engaging football athletes in the evaluation of the intervention program. The objective of this implementation-effectiveness study is to evaluate the effectiveness of the intervention program on reducing exposure in practices and its effect on mitigating changes in clinical outcomes, while monitoring the implementation process. In Aim 1, measures of neurocognition, postural control, and vestibular/ocular motor symptoms will be evaluated from athletes participating on control and intervention youth football teams as well as non-contact sports teams at pre- and post-season time points. Biomechanical data informing the frequency and severity of hits during the season will be measured using a custom instrumented mouthpiece. The effectiveness of the intervention at reducing head impact exposure and mitigating changes in clinical outcomes will be evaluated. In Aim 2, the feasibility and potential utility of the implementation strategy of the intervention program will be assessed to inform intervention program outcomes. Former youth football players participating at the high school and collegiate level will be engaged to evaluate the feasibility and acceptability of the intervention program. The results of this study will provide important pilot data on the effect of reducing exposure on clinical outcomes, while informing how the intervention program works and providing valuable insight into future large-scale testing of the intervention. The predoctoral Candidate will achieve the study aims through cross-disciplinary mentorship in injury biomechanics, public health, implementation science, neuropsychology, and sports medicine. This fellowship opportunity will also provide robust didactic training and experiential learning in traumatic brain injury, methods of biomechanical data collection and implementation science, biostatistics, clinical trials design, neurocognitive test administration and interpretation, and professional development. The research and training plan of this Predoctoral Fellowship will position the Candidate for success as a productive independent research scientist with a skillset to combine injury biomechanics and public health to assess injury prevention strategies.

项目概要 接触运动中重复性头部撞击是一个重大的公共卫生问题，因为它们具有潜在的关联性 患有短期和长期神经功能缺损。研究人员对于其数量存在争议 可能导致神经认知变化的暴露；一些研究人员已经证明这些改变 可能发生在一个赛季的时间内。青少年足球运动员占参赛运动员总数的70% 运动并在练习过程中经历一半以上的头部冲击——这是一个易于干预的环境。 当前的一项研究 (1K25HD101686-01A1) 将开发一种基于证据的干预措施，旨在减少头部 使用社区参与的方法在实践中影响暴露。该提案加强了家长研究 通过纳入临床结果评估并让足球运动员参与干预评估 程序。本实施效果研究的目的是评估实施效果 减少实践中接触的干预计划及其对缓解临床变化的影响 成果，同时监督实施过程。在目标 1 中，神经认知、姿势的测量 控制和前庭/眼部运动症状将由参加控制和眼运动的运动员进行评估 在赛季前和赛季后时间点对青少年足球队以及非接触式运动队进行干预。 告知赛季期间击球频率和严重程度的生物力学数据将使用 定制仪器吹嘴。干预措施在减少头部撞击暴露方面的有效性和 将评估缓解临床结果变化的情况。在目标 2 中，该方案的可行性和潜在效用 将评估干预计划的实施策略，以告知干预计划的结果。 参加高中和大学级别的前青少年足球运动员将参与评估 干预计划的可行性和可接受性。这项研究的结果将提供重要的试点数据 减少暴露对临床结果的影响，同时告知干预计划如何运作以及 为未来大规模干预测试提供有价值的见解。博士前候选人将 通过损伤生物力学、公共卫生、 实施科学、神经心理学和运动医学。该奖学金机会还将提供 创伤性脑损伤的强有力的教学培训和体验式学习、生物力学数据方法 收集和实施科学、生物统计学、临床试验设计、神经认知测试管理和 口译和专业发展。本次博士前奖学金的研究和培养计划将 将成功的候选人定位为一名富有成效的独立研究科学家，并具备将各种技能结合起来的技能 伤害生物力学和公共卫生来评估伤害预防策略。