Centers for AIDS Research (CFAR)

艾滋病研究中心 (CFAR)

• 批准号: 10673760
• 负责人: Susanna Naggie
• 金额: $ 279.89万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10673760
• 关键词: AIDS prevention; Acceleration; Acquired Immunodeficiency Syndrome; Address; Advisory Committees; Area; Basic Science; Censuses; Clinical; Clinical Investigator; Collaborations; Communication; Communities; Community Outreach; Development; Education; Ensure; Environment; Epidemic; Equity; Evolution; Faculty Recruitment; Fostering; Foundations; Funding; Goals; Grant; Growth; HIV; HIV/AIDS; Individual; Infection; Infrastructure; Institution; Investments; Lead; Leadership; Learning; Mental Health; Mentors; Mentorship; Methodology; Mission; NIH Office of AIDS Research; Operative Surgical Procedures; Organ; Persons; Policies; Prevention; Prevention Research; Process; Qualifying; Research; Research Personnel; Research Priority; Research Support; Resource-limited setting; Resources; Role; Services; Solid; Strategic Planning; Substance abuse problem; Training; Translating; United States National Institutes of Health; Universities; Vaccine Design; base; co-infection; community engagement; comorbidity; diversity and inclusion; driving force; fortification; gender diversity; health disparity; improved outcome; innovation; medical schools; member; next generation; opioid epidemic; outreach program; programs; racial diversity; recruit; skills; success; synergism; translational scientist; treatment research; vaccine evaluation

PROJECT SUMMARY – Duke Center for AIDS Research (Overall) The principal mission of the Duke Center for AIDS Research (CFAR) is to establish and grow comprehensive infrastructure support for a research environment that will effectively promote collaboration, coordination, and innovation throughout the Duke HIV/AIDS research community and across the national CFAR network. As evidenced by the growth in our NIH-Funded Research Base that now qualifies us as a Tier 2 CFAR, this competitive renewal application represents an evolution that builds upon our accomplishments and lessons learned during the previous funding cycles, taking advantage of the synergies established among our Core components. A solid basis is formed by our highly successful Pilot Grant mechanism, aimed primarily at Early Stage Investigators, and our equally successful faculty recruitment efforts, both of which have facilitated greater gender and racial diversity. The driving force behind all of our evolving support services is a highly active and effective Strategic Planning process, led by our Executive Committee (EC), with valuable input from both our advisory committees and our intramural Strategic Partners. This highly iterative process has identified five Specific Aims to guide the CFAR's growth and evolution over the next 5 years: 1) Provide comprehensive infrastructure support to all intramural HIV/AIDS investigators aimed at expanding the robust program of inter- disciplinary, collaborative HIV research that addresses NIH Research priorities. 2) Continue development of a pipeline of next generation HIV/AIDS investigators through strong support of Early Stage Investigators and engagement of established investigators from outside the field of HIV/AIDS research. 3) Foster critical synergies through Core-Core interactions and engagement of new and existing Strategic Partnerships. 4) Expand the relevance, reach, and impact of HIV/AIDS research by implementing and supporting community engagement and outreach. 5) Further enhance and support collaborative activities throughout the global network of CFARs. Support services will be enhanced by increased institutional support from Duke's School of Medicine and Department of Surgery. Through our Strategic Planning process, we have identified eight priority areas that represent opportunities for further development during the next funding cycle. These include: 1) the `Southern HIV Epidemic'; 2) HIV Co-Morbidities, Co-Infections, and Complications; 3) Latency and Eradication; 4) Health Disparities; 5) Vaccine Design and Evaluation; 6) Mental Health and Substance Abuse; 7) the HIV Organ Policy Equity (HOPE) Act; and 8) Emerging Infections. Finally, to ensure the continued high-quality support for intramural HIV/AIDS investigators, the EC has formulated a Leadership Transition Plan, vetted by the institution, in which Dr. Georgia Tomaras and Dr. Susanna Naggie will become Director and Co-Director, respectively. The CFAR looks forward to developing and exploring these timely opportunities within Duke and across the CFAR network throughout the next funding cycle.

项目摘要——杜克艾滋病研究中心（总体） 杜克大学艾滋病研究中心 (CFAR) 的主要使命是建立和发展综合性的艾滋病研究中心 对研究环境的基础设施支持，将有效促进合作、协调和 杜克大学艾滋病毒/艾滋病研究界和国家 CFAR 网络的创新。 我们 NIH 资助的研究基地的发展证明了我们现在有资格成为二级 CFAR，这 竞争性更新应用程序代表了基于我们的成就和经验教训的演变 利用我们核心之间建立的协同作用，在之前的融资周期中学到的知识 我们非常成功的试点资助机制奠定了坚实的基础，主要针对早期。 阶段调查员，以及我们同样成功的教师招聘工作，两者都促进了 我们所有不断发展的支持服务背后的驱动力是高度的性别和种族多样性。 积极有效的战略规划流程，由我们的执行委员会 (EC) 领导，并提供了宝贵的意见 我们的咨询委员会和内部战略合作伙伴都已确定了这一高度迭代的过程。 指导 CFAR 在未来 5 年发展和演变的五个具体目标： 1) 提供全面的 向所有校内艾滋病毒/艾滋病调查员提供基础设施支持，旨在扩大内部艾滋病毒/艾滋病调查员的强有力的计划 解决 NIH 研究重点的学科、协作性艾滋病毒研究 2) 继续开发一个 通过早期研究人员的大力支持，培养下一代艾滋病毒/艾滋病研究人员 来自艾滋病毒/艾滋病研究领域之外的知名研究人员的参与 3) 培养关键人员。 通过核心与核心的互动以及新的和现有的战略伙伴关系的参与产生协同效应4)。 通过实施和支持社区扩大艾滋病毒/艾滋病研究的相关性、范围和影响 5) 进一步加强和支持全球范围内的合作活动。 杜克大学的机构支持将增强 CFAR 网络。 通过我们的战略规划流程，我们确定了医学和外科部门的八个优先事项。 代表下一个融资周期进一步发展机会的领域包括： 1) “南方艾滋病毒流行”；2) 艾滋病毒合并症、合并感染和并发症；3) 潜伏期和根除； 4) 健康差异；5) 疫苗设计和评估；6) 心理健康和药物滥用； 器官政策公平 (HOPE) 法案；以及 8) 新出现的感染。 为了支持校内艾滋病毒/艾滋病调查人员，欧盟委员会制定了一项领导权过渡计划，并经过 Georgia Tomaras 博士和 Susanna Naggie 博士将担任该机构的主任和联合主任， CFAR 期待在杜克大学和 在整个 CFAR 网络中，整个下一个融资周期。