Institutional Career Development Core

机构职业发展核心

• 批准号: 10668336
• 负责人: Thomas H. Kelly
• 金额: $ 88.02万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10668336
• 关键词: Acceleration; Address; Arts; Biomedical Research; Clinical; Clinical Research; Clinical Sciences; Communities; Competence; Complex; Dentistry; Discipline; Discipline of Nursing; Education; Educational Curriculum; Educational Technology; Elderly; Engineering; Extramural Activities; Faculty; Foundations; Funding; Future; Growth; Health; Health Sciences; Human; Individual; Institution; Kentucky; Leadership; Longevity; Medical Students; Medicine; Mentors; Monitor; Pharmacy facility; Policies; Principal Investigator; Process; Public Health; Publishing; Research; Research Methodology; Research Training; Science; Time; Training; Training Programs; Training Support; Translational Research; Underrepresented Minority; United States National Institutes of Health; Universities; biomedical informatics; career; career development; clinical center; cohort; college; design; experience; improved; instructor; interest; multidisciplinary; next generation; prenatal; programs; research and development; skills; undergraduate student

PROJECT SUMMARY – KL2 INSTITUTIONAL CAREER DEVELOPMENT The University of Kentucky Center for Clinical and Translational Science (CCTS) proposes to sustain and enhance the current KL2 program, currently in its ninth year of National Institutes of Health (NIH) support. By providing two to three years of release time (75% effort) and research funding support for mentored career development, the program is designed to accelerate the academic growth for the next generation of leaders in clinical and translational research (CTR). The program has four programmatic objectives: 1) to provide a curriculum that meets core training needs of CTR scholars, 2) to support a mentored program of research training that expedites development of research careers, 3) to support personalized training programs that expedite CTR career development, and 4) to provide continuous assessment and quality improvement of both individual scholar career development and overall KL2 program. The program has garnered strong institutional support; across the nine years, the initial two NIH-supported training slots have been expanded to seven slots (four NIH-supported, three institutionally supported). The program supports career development of scholars with research interests that cross the lifespan (prenatal through elderly) and the full spectrum of clinical and translational science, including translational, clinical, community/policy studies and clinical and translational research (CTR) methods/processes (e.g., biomedical informatics) focusing on a broad array of health topics. Scholars and mentors represent a wide range of disciplines and colleges including Medicine, Nursing, Dentistry, Pharmacy, Health Sciences, Public Health, Education, Engineering and Arts and Sciences. All program graduates (n=18) remain actively engaged in CTR, have made important contributions to science through published research and have successfully competed for extramural funding with 14 as principal investigators. We are requesting renewed NIH support of four KL2 scholar training slots. The training of a minimum of three additional institutionally sponsored early-career scholars will continue to be fully integrated with these NIH-supported scholars to sustain a cohort of at least seven scholars. The foundation of the proposed program will continue to be practical research experiences within multidisciplinary teams guided by experienced mentors, with a Faculty Oversight Committee monitoring the successful career development of these future CTR leaders. Educational technology promotes vigorous yet efficient competency training programs. Further, our enhanced team science training programs will focus specifically on developing leadership skills. Institutionally sponsored pipeline programs targeting undergraduates, medical students, residents, fellows and clinical instructors, several focused on underrepresented minorities, will support the availability of a strong and diverse pool of candidates for the KL2 program. In sum, the KL2 program is accelerating the career development of future leaders of the biomedical research workforce who are well prepared to address today’s complex research challenges and spearhead future advances in human health.

项目摘要 – KL2 机构职业发展 肯塔基大学临床和转化科学中心 (CCTS) 建议维持和 加强当前的 KL2 计划，该计划目前已进入美国国立卫生研究院 (NIH) 支持的第九个年头。 为指导职业提供两到三年的发布时间（75% 的努力）和研究经费支持 发展，该计划旨在加速下一代领导者的学术成长 该计划有四个计划目标：1) 提供 满足 CTR 学者核心培训需求的课程，2) 支持指导性研究计划 加速研究职业发展的培训，3) 支持个性化培训计划 加快 CTR 职业发展，以及 4) 提供持续评估和质量改进 个人学者的职业发展和整体 KL2 项目吸引了强大的机构。 九年来，NIH 支持的最初两个培训名额已扩大到七个 （四项由 NIH 支持，三项由机构支持）。 具有跨生命周期（从产前到老年）的研究兴趣以及全方位的临床和 转化科学，包括转化、临床、社区/政策研究以及临床和转化 研究（CTR）方法/过程（例如生物医学信息学）专注于广泛的健康主题。 学者和导师代表了广泛的学科和学院，包括医学、护理、 牙科、药学、健康科学、公共卫生、教育、工程以及艺术和科学。 项目毕业生 (n=18) 仍然积极参与 CTR，为科学做出了重要贡献 通过发表的研究成果，并以 14 名校长的身份成功竞争校外资助 我们请求 NIH 重新支持 4 名 KL2 学者培训名额。 至少三名额外的机构资助的早期职业学者将继续完全融入 与这些 NIH 支持的学者一起维持了至少七名学者的基础。 拟议的计划将继续是多学科团队内的实际研究经验 经验丰富的导师，并设有教员监督委员会，负责监督导师的成功职业发展 这些未来的 CTR 领导者将促进充满活力且高效的能力培训。 此外，我们增强的团队科学培训计划将专门侧重于开发。 机构资助的针对本科生、医学院学生的领导技能项目。 住院医生、研究员和临床讲师（其中一些人关注的是代表性不足的少数群体）将支持 KL2 计划拥有强大且多样化的候选人库。 总之，KL2 计划是。 加速生物医学研究人员未来领导者的职业发展 准备应对当今复杂的研究挑战并引领人类健康的未来进步。

项目成果

Intra-arterial combination therapy for experimental acute ischemic stroke.

实验性急性缺血性中风的动脉内联合治疗。

• 发表时间: 2022
• 作者: Maniskas, Michael E;Roberts, Jill M;Gorman, Amanda;Bix, Gregory J;Fraser, Justin F
• 通讯作者: Fraser, Justin F

Sex, diabetes status and cognition: findings from the study of longevity in diabetes.

性别、糖尿病状况和认知：糖尿病长寿研究的结果。

• 发表时间: 2021
• 影响因子: 4.1
• 作者: Moran, Chris;Gilsanz, Paola;Beeri, Michal S;Whitmer, Rachel A;Lacy, Mary E
• 通讯作者: Lacy, Mary E

Association of Type 1 Diabetes and Hypoglycemic and Hyperglycemic Events and Risk of Dementia.

1 型糖尿病与低血糖和高血糖事件以及痴呆风险的关联。

• 发表时间: 2021-07-19
• 影响因子: 9.9
• 作者: Whitmer, Rachel A;Gilsanz, Paola;Quesenberry, Charles P;Karter, Andrew J;Lacy, Mary E
• 通讯作者: Lacy, Mary E

Association of Sex and Race With Incident Peripheral Artery Disease Among Veterans With Normal Ankle-Brachial Indices.

踝臂指数正常的退伍军人中性别和种族与外周动脉疾病的关系。

• 发表时间: 2022-11-01
• 影响因子: 13.8
• 作者: Aday, Aaron W;Duncan, Meredith S;Patterson, Olga V;DuVall, Scott L;Alba, Patrick R;Alcorn, Charles W;Tindle, Hilary A;Creager, Mark A;Bonaca, Marc P;Damrauer, Scott M;Wells, Quinn S;Behroozian, Adam;Beckman, Joshua A;Freiberg, Matthew S
• 通讯作者: Freiberg, Matthew S

Factors Associated With Long-Term Quadriceps Muscle Function After Surgical Fixation of Lower Extremity Fractures.

下肢骨折手术固定后与长期股四头肌功能相关的因素。

• 发表时间: 2023-10-03
• 影响因子: 3.2
• 作者: Brightwell, Benjamin D;Van Wyngaarden, Joshua J;Samaan, Michael A;Matuszewski, Paul E;Jacobs, Cale A;Noehren, Brian
• 通讯作者: Noehren, Brian