Bridging the Gap to Enhance Clinical Research Program (BIGGER)

弥合差距，加强临床研究计划（BIGGER）

基本信息

批准号：
9228683
负责人：
VIVIAN H CHU
金额：
$ 9.74万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-12-15 至 2021-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9228683
关键词：
Acceleration Address Affect African American Area Arts Attention Cardiac Cardiovascular Diseases Cardiovascular system Caring Cause of Death Child Clinical Clinical Research Communication Complement Databases Drug Kinetics Education Educational Curriculum Educational workshop Effectiveness Enrollment Ensure Environment Faculty Fostering Funding Future Genetic Markers Goals Grant Health Health Professional Health Sciences Heart Diseases Heart failure High School Student Implantable Defibrillators Individual Infective endocarditis Interview Investigation Leadership Learning Medical Medical Students Mentors Mentorship Methods North Carolina Online Systems Participant Pharmaceutical Preparations Population Heterogeneity Positioning Attribute Prevention Principal Investigator Public Health Recruitment Activity Research Research Ethics Research Infrastructure Research Institute Research Methodology Resources Review Literature Running Schools Science Scientist Solid Structure Students Training Training Programs Training Support Underrepresented Minority Underrepresented Students United States United States National Institutes of Health Universities Vulnerable Populations Work Writing base cardiovascular risk factor career career development college congenital heart disorder curriculum development ethnic diversity experience faculty mentor hands on research health disparity high school improved knowledge base medical schools member method development mid-career faculty older patient programs public health relevance racial disparity racial diversity research and development skills success summer research symposium tool development undergraduate student

项目摘要

Project Summary/Abstract The BrIdGing the Gap to Enhance Clinical Research Program (referred to henceforth as the “BIGGER” program) will provide a high-quality research experience for students in their gap year, defined as the period after college graduation and prior to enrollment in graduate/professional school. The program will comprise a partnership between Duke University, the University of North Carolina, and North Carolina Central University (the nation’s first liberal arts college founded for African Americans) to enhance the diversity of the clinical research workforce, thereby ensuring that health concerns of underrepresented minorities remain a part of the national research agenda. Students will be exposed to a hands-on research experience that will encourage future research careers, and they will obtain career development tools to foster professional success. The program will expand and complement NIH-sponsored training resources already in place at Duke University under the leadership of the principal investigators, Dr. Kevin Thomas and Dr. Vivian Chu. This leadership structure synergistically combines scientific expertise and connections in cardiovascular disease (Dr. Thomas) with clinical research and career development curriculum expertise (Dr. Chu). In addition, the Duke Clinical Research Institute (DCRI) offers formal educational and support programs for junior faculty, fellows, residents, medical students, undergraduates, and high school students, with funding from internal DCRI resources as well as the NIH. The proposed program represents a unique piece in a continuum of NIH-supported training at the DCRI that runs the gamut from the high school-level to mid-career faculty. While the proportion of gap-year students is increasing, there are limited opportunities for these students to engage in a meaningful, career development experience. This program will be ideally positioned to fill this need using an established educational infrastructure with a track record of successful trainees. The program will take place over 6 months. Each participant will be paired with a senior Duke faculty mentor and will be integrated into the work of the mentor’s team for a collaborative research experience. Participants will work on an individual scholarly project, which will be original and hypothesis-driven. For the first 3 weeks of the program, trainees will work with their faculty mentors to develop a solid knowledge base of a specific clinical question based on a thorough review of the literature. During weeks 4-22, the trainees will develop a 6- page thesis consisting of a description of the research question, specific aims, methods, and figures/tables for the study. Throughout the program, didactics will focus on clinical research methods, research ethics, and writing skills and will be taught by Duke faculty and a dedicated medical writer. Trainees will work with their mentors throughout the course of the program to review their progress and the scientific validity of their work. At the conclusion of the program, trainees will present the results of their work to the faculty and staff at the DCRI. Finally, trainees will be followed for 10 years using a web-based database to assess the effectiveness of the training program. The proposed program will result in an improved, more diverse pipeline of future scientists whose practical experience in clinical research will facilitate their entry into research careers.

项目概要/摘要弥合差距以加强临床研究计划（以下简称“BIGGER”）计划）将为学生在间隔年（定义为间隔年）提供高质量的研究体验大学毕业后和进入研究生/专业学校之前该计划将包括杜克大学、北卡罗来纳大学和北卡罗来纳中央大学之间的合作伙伴关系（美国第一所为非裔美国人建立的文理学院）以增强临床的多样性研究队伍，从而确保代表性不足的少数群体的健康问题仍然是研究的一部分国家研究议程。学生将获得实践研究经验，这将鼓励未来的研究职业，他们将获得职业发展工具来促进职业成功。该计划将扩展和补充 NIH 赞助的杜克大学现有培训资源在首席研究员 Kevin Thomas 博士和 Vivian Chu 博士的领导下。结构协同结合了心血管疾病领域的科学专业知识和联系（托马斯博士）具有临床研究和职业发展课程的专业知识（朱博士）。研究所 (DCRI) 为初级教师、研究员、住院医师、医学生、本科生和高中生，资金来自 DCRI 内部资源：拟议的计划代表了 NIH 支持的一系列培训中的独特部分。 DCRI 覆盖了从高中到职业生涯中期的教师，而间隔年的比例。学生人数不断增加，这些学生从事有意义的职业的机会有限该计划将非常适合利用既定的开发经验来满足这一需求。具有成功学员记录的教育基础设施。该项目将持续 6 个月以上，每位参与者都将与一位杜克大学高级教师导师配对。并将融入导师团队的工作中，以获得合作研究经验。将在前三周开展一个个人学术项目，该项目将是原创且以假设为驱动的。在该计划中，学员将与他们的导师合作，为特定领域建立坚实的知识基础在第 4 至 22 周期间，学员将根据对文献的全面回顾提出临床问题。论文由研究问题的描述、具体目标、方法和图表组成在整个研究过程中，教学将重点关注临床研究方法、研究伦理和写作技巧将由杜克大学的教师教授，一名专门的医学作家将与他们一起工作。全程指导该计划的进程，以审查他们的进展及其工作的科学有效性。课程结束时，学员将向学院的教职员工展示他们的工作成果最后，DCRI 将使用基于网络的数据库对学员进行为期 10 年的跟踪，以评估其有效性。拟议的培训计划将导致未来的管道更加完善、更加多样化。临床研究实践经验将有助于他们进入研究生涯的科学家。