LOOK AHEAD: ACTION FOR HEALTH IN DIABETES

展望未来：糖尿病健康行动

• 批准号: 7731311
• 负责人: DAVID M NATHAN
• 金额: $ 0.5万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731311
• 关键词: Body Weight decreased; Cardiovascular system; Computer Retrieval of Information on Scientific Projects Database; Control Groups; Diabetes Mellitus; Education; Energy Intake; Event; Funding; Grant; Health; Incidence; Institution; Intervention; Long-Term Effects; Metabolic; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Overweight; Physical activity; Research; Research Personnel; Resources; Risk Factors; Source; United States National Institutes of Health; cardiovascular disorder risk; cost effectiveness; design; intervention program; lifestyle intervention; programs; volunteer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of Look AHEAD is to examine, in overweight volunteers with type 2 diabetes, the long-term effects of an intensive lifestyle intervention program designed to achieve and maintain weight loss by decreased caloric intake and increased physical activity. This program is compared to a control group receiving diabetes support and education. The primary outcome, which will be compared between the two treatment groups, is the incidence of serious cardiovascular events. Other outcomes include cardiovascular disease risk factors, diabetes-related metabolic factors and complications, and cost-effectiveness of the intensive intervention.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 展望的主要目的是检查，在患有2型糖尿病的超重志愿者中，强化生活方式干预计划的长期影响旨在通过减少热量摄入和增加体育锻炼来实现和维持体重减轻。 将该计划与接受糖尿病支持和教育的对照组进行比较。 两个治疗组之间将进行比较的主要结果是严重的心血管事件的发生率。 其他结果包括心血管疾病危险因素，与糖尿病相关的代谢因素和并发症以及强化干预的成本效益。