DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)

糖尿病预防计划成果研究 (DPPOS)

• 批准号: 7607036
• 负责人: DAVID M NATHAN
• 金额: $ 0.26万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607036
• 关键词: Body Weight decreased; Clinical Trials; Complications of Diabetes Mellitus; Computer Retrieval of Information on Scientific Projects Database; Diabetes Mellitus; Funding; Grant; Health; Institution; Intervention; Lead; Metformin; Non-Insulin-Dependent Diabetes Mellitus; Outcome Study; Pharmaceutical Preparations; Placebos; Rate; Research; Research Personnel; Resources; Risk; Source; United States National Institutes of Health; diabetes prevention program; diet and exercise; prevent; volunteer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DPPOS is a nationwide clinical trial studying whether weight loss through diet and exercise or the diabetes medication metformin can continue to prevent or delay type 2 diabetes in high-risk volunteers who participated in the Diabetes Prevention Program. The hypotheses are that these interventions will result in lower rates of diabetes in former DPP intervention groups compared with the former placebo group; and preventing or delaying diabetes will lead to better health and a reduction in diabetes complications.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 DPPO是一项全国范围内的临床试验，研究是否通过饮食和运动减肥或糖尿病药物二甲双胍可以继续预防或延迟参加预防糖尿病预防计划的高风险志愿者中2型糖尿病。假设是，与以前的安慰剂组相比，这些干预措施将导致以前的DPP干预组的糖尿病率较低。 并且预防或延迟糖尿病将导致更好的健康状况和糖尿病并发症的降低。