Amblyopia in Astigmatic Children-Development & Treatment

散光儿童发育中的弱视

• 批准号: 7473866
• 负责人: Erin M Harvey
• 金额: $ 69.41万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7473866
• 关键词: Age; Age-Years; Amblyopia; Astigmatism; Blur; Child; Child Development; Clinical; Coma; Condition; Cornea; Development; Effectiveness; Eyeglasses; General Population; Goals; Guidelines; High Prevalence; Infant; Literature; Low Prevalence; Native Americans; Nursery Schools; Optics; Population; Prevention; Refractive Errors; Research; Research Personnel; Risk; School-Age Population; Time; Toddler; Tribes; United States Public Health Service; Visual; Visual Acuity; Visual system structure; deprivation; early childhood; experience; infancy; treatment effect; vision development; visual deprivation

The detrimental effects of uncorrected astigmatism on visual development are well documented: blur induced by uncorrected astigmatism results in visual deficits that persist despite optical correction. Partnership with the Tohono O'odham Nation, a Native American tribe with a high prevalence of high astigmatism has allowed researchers to conduct large-scale studies of preschool- and school-aged children with high astigmatism. However, little is known about the development of astigmatism and astigmatism- related amblyopia prior to age 3 years. The goals of the present study are: Goal 1. To document developmental changes in astigmatism and aberrations in infants and young children from a population with a high prevalence of high astigmatism. Goal 2. To determine the relation between quality of visual experience (quality of visual input) in astigmatic and non-astigmatic infants and toddlers and visual development (normal and abnormal/amblyopic). Goal 3. To determine the relation between spherical aberration and coma and corrected visual acuity in young children with and without high astigmatism. Goal 4. To determine the effectiveness of eyeglass treatment of astigmatism-related amblyopia in young children. The proposed study will provide unique and valuable information on the development of astigmatism and aberrations and their effects on visual development, will generate important clinical information to aid in the development of guidelines for treatment and prevention of astigmatism-related amblyopia in infancy and early childhood, and will provide a valuable public health service for a population whose children are at increased risk for the development of amblyopia.

未矫正散光对视觉发育的不利影响已有充分记录：模糊 未经矫正的散光引起的视力缺陷尽管进行了光学矫正，但仍然持续存在。 与 Tohono O'odham 民族合作，这是一个高患病率的美洲原住民部落 散光使得研究人员能够对学龄前和学龄儿童进行大规模研究 患有高度散光。然而，对于散光的发展和散光却知之甚少—— 3岁之前有相关性弱视。本研究的目标是： 目标 1. 记录婴儿和青少年散光和像差的发育变化 来自高度散光患病率较高人群的儿童。 目标 2. 确定视觉体验质量（视觉输入质量）之间的关系 散光和非散光婴儿和幼儿与视觉发育（正常和 异常/弱视）。 目标 3. 确定球差和慧差与矫正视力之间的关系 患有或不患有高度散光的幼儿。 目标 4. 确定眼镜治疗散光相关弱视的有效性 年幼的孩子。 拟议的研究将为散光和散光的发展提供独特且有价值的信息。 像差及其对视觉发育的影响，将产生重要的临床信息，以帮助 制定治疗和预防婴儿期散光相关弱视的指南 幼儿期，并将为儿童处于幼儿期的人群提供宝贵的公共卫生服务 增加发生弱视的风险。