Developmental Research Program

发展研究计划

• 批准号: 7511016
• 负责人: Wilma Lingle
• 金额: $ 9.26万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7511016
• 关键词: Address; Adult; Advisory Committees; American Cancer Society; Applications Grants; Appointment; Area; Award; Biochemistry; Biology; Biomedical Engineering; Blood Vessels; Chicago; Clinic; Clinical; Clinical Research; Clinical Trials; Communities; Creativeness; Data; Development; Diagnosis; Doctor of Philosophy; Extramural Activities; Foundations; Funding; Future; Generations; Goals; Grant; Human Resources; Illinois; India; Institution; International; Journals; Laboratories; Leadership; Letters; Malignant neoplasm of pancreas; Mayo Clinic Cancer Center; Medicine; Mentors; Molecular Biology; Nanotechnology; National Cancer Institute; Numbers; Patients; Peer Review; Personal Satisfaction; Population; Positioning Attribute; Postdoctoral Fellow; Process; Program Description; Program Development; Program Research Project Grants; Publications; Reproduction spores; Request for Applications; Research; Research Design; Research Peer Review; Research Personnel; Research Project Grants; Research Proposals; Resources; Scientist; Score; Screening procedure; Secure; Senior Scientist; Stimulus; Students; Study Section; Testing; Translating; Translational Research; Tumor Angiogenesis; United States National Institutes of Health; Universities; anticancer research; base; career; clinically relevant; college; design; experience; innovation; insight; interdisciplinary collaboration; medical schools; novel; originality; professor; programs; sound; success; volunteer

The Mayo Clinic SPORE in Pancreatic Cancer Research will continue to make every effort to maximize the number of innovative and high-quality projects in the Developmental Research Program (DRP). The goal of the DRP is to support innovative, scientifically sound research projects from which findings can be translated into clinically relevant applications that will impact screening, diagnosis, and management of pancreatic cancer. Progress over the past funding period has resulted in support for 15 of 45 DRP applications. These meritorious projects have yielded important new insights about pancreatic cancer and to extramural funding, including contributions to the full translational research projects in this current SPORE application. The DRP will: (1) encourage and solicit innovative translationally-relevant laboratory, population and cfinical study proposals; (2) encourage and support interdisciplinary collaboration in translational research in pancreatic cancer; and (3) generate new hypotheses that can be tested in larger-scale research projects or clinical trials that can impact pancreatic cancer. The DRP will provide up to $50,000 (utilizing funds from both the SPORE grant and institutional resources) to 3 to 5 projects annually. There will be the possibility of a second year of support based on progress. A process has been successfully established to call for applications on an annual basis and to formally peer review submissions utilizing the expertise of the Scientific Advisory Committee and other experienced investigators. Criteria will be based upon scientific merit, originality, qualifications of the key personnel and interactions, and translational potential. It is our experience, and will continue to be anticipated, that support of developmental research projects will result in the generation of new hypotheses that can potentially be addressed in existing SPORE-sponsored projects, or through peer reviewed external grant support. It is the intent of the SPORE leadership to encourage and help the investigators to use the data generated by these projects to design either R01-type grants or Program Project Grant proposals in the next funding period.

胰腺癌研究中的梅奥诊所孢子将继续付出一切努力，以最大化 发展研究计划（DRP）中创新和高质量项目的数量。目标 DRP旨在支持创新的，科学上合理的研究项目，可以从中翻译发现 进入临床相关的应用，这些应用会影响胰腺的筛查，诊断和管理 癌症。在过去的资金期间，进展已导致支持45个DRP应用中的15个。这些 有功的项目产生了有关胰腺癌和壁外资金的重要新见解， 在当前的孢子应用程序中包括对完整的翻译研究项目的贡献。 DRP 威尔：（1）鼓励和征求创新的翻译实验室，人口和研究 建议； （2）鼓励和支持胰腺翻译研究的跨学科合作 癌症; （3）产生可以在大型研究项目或临床试验中进行测试的新假设 这可能会影响胰腺癌。 DRP最多可提供50,000美元（利用两个孢子的资金 授予和机构资源）每年3至5个项目。将有可能第二年 基于进度的支持。已经成功建立了一个过程，以呼吁 使用科学咨询的专业知识，年度基础和正式同行评审提交 委员会和其他经验丰富的调查员。标准将基于科学优点，独创性， 关键人员和互动的资格以及翻译潜力。这是我们的经验，将 继续预期，发展研究项目的支持将导致产生 可能在现有的孢子赞助的项目中或通过同行中解决的新假设 审查外部赠款支持。这是孢子领导的意图，以鼓励和帮助 调查人员使用这些项目生成的数据来设计R01型赠款或计划 在下一个资金期间，项目赠款提案。