Tissue & Cell

组织

基本信息

批准号：
7944933
负责人：
Wilma Lingle
金额：
$ 14.75万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-04-17 至 2014-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7944933
关键词：
Accounting Antibodies Antigens Archives Area Benign Brightfield Microscopy Buffers Caliber Cancer Center Cells Chemistry Citrates Client Clinic Comprehensive Cancer Center Computer Interface Computer Systems Computer software Cryoultramicrotomy Custom DNA Ploidy Analysis Data Files Databases Detection Development Digestion Documentation Edetic Acid Electronics Ensure Equipment Event Fluorescence Fluorescence Microscopy Freezing Fresh Tissue Frozen Sections Future Genes Glass Goals Grant Growth Heating Histology Hour Human Resources Image Image Analysis Immunofluorescence Microscopy Immunohistochemistry In Situ Hybridization Individual Instruction Intranet Laboratories Lasers Link Location Manuals Mayo Clinic Cancer Center Membrane Microscope Microscopy Microtome - medical device Molds Molecular Analysis Noise Nucleic Acids Operative Surgical Procedures Output Paraffin Paraffin Embedding Pathologist Pathology Peptide Hydrolases Peptides Persons Positioning Attribute Preparation Principal Investigator Printing Procedures Process Protein Analysis Proteins Protocols documentation RNA Records Research Research Personnel Resolution Resource Sharing Retrieval Sampling Scanning Scheme Services Signal Transduction Site Slide Source Specimen Staging Staining and Labeling Staining method Stains System Techniques Thick Tissue Microarray Tissues Tracer Training Tube antibody conjugate anticancer research base digital digital imaging fluorophore improved instrument laser capture microdissection member programs tissue preparation tissue processing tumor virtual

项目摘要

The goal of the Tissue and Cell Molecular Analysis (TACMA) Shared Resource of the Mayo Clinic Cancer Center is to provide histological and related tissue-based services to Cancer Center investigators. The TACMA Shared Resource is a source of expertise and collaborative support for Cancer Center investigators, providing services for preparation of histology slides for microscopy, tissue microarray construction, immunostaining, digital image capture and analysis, laser capture microdissection, and preparation of tissues for subsequent nucleic acid or protein extraction. Since 2003, the number of Cancer Center members who have used services provided by the TACMA Shared Resource increased from 84 to 97 (15%). More importantly, the level of use of the four of the five major TACMA services by Cancer Center members increased 33%, 71%, 100%, and 209% and the other major service had modest growth of 7%. Cancer Center members continue to account for more than 50% of the total demand for each service offered by TACMA. This growth has been achieved by adding technical staff positions, by expanding hours of operation, and by purchasing additional equipment in order to increase our capacity for services in keeping with the demand for services. The services provided by the TACMA Shared Resource have been vital to cancer research at Mayo Clinic.

梅奥诊所癌症组织和细胞分子分析 (TACMA) 共享资源的目标中心将为癌症中心研究人员提供组织学和相关组织服务。这 TACMA 共享资源是癌症中心研究人员的专业知识和协作支持的来源，提供用于显微镜、组织微阵列构建的组织学载玻片制备服务，免疫染色、数字图像捕获和分析、激光捕获显微切割以及制备用于后续核酸或蛋白质提取的组织。自 2003 年以来，癌症中心数量使用过 TACMA 共享资源提供的服务的会员从 84 名增加到 97 名（15%）。更重要的是，癌症中心成员对五项主要 TACMA 服务中的四项的使用水平增长了 33%、71%、100% 和 209%，其他主要服务略有增长 7%。癌症中心会员继续占中心提供的各项服务总需求的50%以上塔克玛。这一增长是通过增加技术人员职位、延长工作时间来实现的运营，并通过购买额外的设备来提高我们的服务能力，以保持随着对服务的需求。 TACMA 共享资源提供的服务对于梅奥诊所的癌症研究。