Implementation of School-Entry Policies for Human Papillomavirus Vaccination

人乳头瘤病毒疫苗接种入学政策落实情况

• 批准号: 10303054
• 负责人: Vivian Colon
• 金额: $ 36.77万
• 依托单位: COMPREHENSIVE CANCER CENTER/ UNIV/PR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10303054
• 关键词: 12 year old; Accounting; Adolescent; Adopted; Adoption; Age; Archives; Back; Case Study; Collaborations; Communities; Consolidated Framework for Implementation Research; Data; Disease; Dissemination and Implementation; District of Columbia; Dose; Effectiveness; Enrollment; Evolution; Female; Focus Groups; Generations; Geographic state; Goals; Government; Grant; HPV-High Risk; Health; Health Personnel; Healthcare; Healthy People 2020; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papilloma Virus-Related Malignant Neoplasm; Human Papillomavirus; Human papilloma virus infection; Immunization; Immunization Programs; Incidence; Infection prevention; Interview; Malignant Vaginal Neoplasm; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Malignant neoplasm of penis; Malignant neoplasm of vulva; Meningococcal vaccine; Methods; Natural experiment; Outcome; Parents; Policies; Positioning Attribute; Preventive vaccine; Procedures; Process; Public Health; Public Policy; Puerto Rico; Qualitative Research; Recommendation; Rectal Cancer; Registries; Reporting; Research; Rhode Island; Sampling; Schools; Source; Students; Surveys; System; Teenagers; Texas; Time; United States Virgin Islands; Vaccination; Vaccines; Variant; Virginia; age group; biological sex; comparative; contextual factors; data registry; design; evidence base; future implementation; geographic difference; high risk; implementation barriers; implementation facilitators; implementation outcomes; implementation research; improved; informant; innovation; male; malignant oropharynx neoplasm; mortality; multilevel analysis; non-compliance; sixth grade

7. Project Summary/Abstract Despite the availability of prophylactic vaccines against HPV, modest increases in vaccination coverage among adolescents has been reported. In Puerto Rico (PR), where disparities in incidence, mortality, and survival of HPV-related cancers have been extensively documented, vaccination rates are low. The PR government recently enacted a policy to require HPV vaccination for all adolescents' ages 11-12 years who enroll in schools, beginning the next academic year (2018-2019). PR became the 5th US state or territory to adopt an HPV vaccine school-entry policy. Taking into account this important public policy implementation, the proposed study aims to examine geographic variation in the dissemination and implementation of HPV vaccine policies across US states and territories, while taking advantage of the timely opportunity to study the implementation and outcomes of the new school-entry HPV policy in PR in depth. This study will use a multi-method approach to analyze survey data, immunization registry data, and qualitative data using a combination of qualitative, correlational, comparative case study, multilevel analysis and natural experiment designs. Additionally, and in collaboration with our local and national partners, the study findings and recommendations will be disseminated back to stakeholders and decision makers to inform the ongoing evolution of the policy implementation in PR and other states with existing policies, and to inform states/territories that are considering adopting a new HPV vaccine school entry policy. Our research team is uniquely positioned to be able to carry this important and time-sensitive study given our long track record and existing collaborations with local and national academic partners and coalitions focusing on HPV vaccination. If granted, this project will serve to inform other states and territories considering HPV immunization policies and future implementation research on these policies. PHS 398/2590 (Rev. 06/09) Project Summary/Abstract Continuation Format Page

7. 项目总结/摘要 尽管有针对 HPV 的预防性疫苗，但疫苗接种覆盖率略有增加 青少年已有报道。在波多黎各 (PR)，发病率、死亡率和生存率存在差异 HPV 相关癌症已被广泛记录，但疫苗接种率较低。民联政府 最近颁布了一项政策，要求所有 11 至 12 岁在校青少年接种 HPV 疫苗， 从下一学年（2018-2019）开始。 PR 成为美国第五个采用 HPV 疫苗的州或地区 入学政策。考虑到这一重要的公共政策实施，拟议的研究旨在 研究美国各州 HPV 疫苗政策传播和实施的地理差异 和领土，同时利用及时的机会研究该计划的实施情况和成果 新入学HPV政策在公关中深入开展。本研究将使用多种方法来分析调查数据， 免疫登记数据以及使用定性、相关性、比较性相结合的定性数据 案例研究、多层次分析和自然实验设计。此外，与我们当地的合作 和国家合作伙伴，研究结果和建议将传播给利益相关者和 决策者向波罗的海州和其他州的政策实施的持续演变提供信息 现有政策，并通知正在考虑采用新的 HPV 疫苗学校入学的州/地区 政策。我们的研究团队具有独特的优势，能够开展这项重要且时间敏感的研究 我们的长期记录以及与地方和国家学术合作伙伴和联盟的现有合作重点 关于 HPV 疫苗接种。如果获得批准，该项目将有助于为其他考虑 HPV 的州和地区提供信息 免疫政策以及这些政策的未来实施研究。 PHS 398/2590（修订版。06/09）项目摘要/摘要延续格式页