OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE

光学和视网膜对人类视觉性能的限制

• 批准号: 7684183
• 负责人: LARRY N THIBOS
• 金额: $ 29.42万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-01-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7684183
• 关键词: 3-Dimensional; Area; Binocular Vision; Cataract; Clinical; Color; Contrast Sensitivity; Cornea; Corneal Diseases; Discrimination; Eye; Film; Goals; Growth; Human; Image; Individual; Lead; Learning; Light; Measurement; Measures; Methodology; Methods; Metric; Minor; Modeling; Mydriasis; Myopia; Nature; Operative Surgical Procedures; Optics; Outcome; Outcome Assessment; Perception; Peripheral; Population; Pupil; Relative (related person); Research; Research Personnel; Resolution; Retinal; Role; Sampling; Science; Series; Simulate; Statistical Models; Stimulus; Structure; System; Technology; Testing; Time; Vision; Visual; Visual Acuity; Visual Fields; base; emmetropization; experience; improved; lens; luminance; monocular; new technology; novel; physical model; programs; research study; spatial vision; three dimensional structure; tomography; tool; visual performance

DESCRIPTION (provided by applicant): The long-term goal of our research program is to understand how optical and retinal factors constrain the quality of visual experience. Our specific aims for the next project period are (1) to expand the scope of wavefront aberrometry into the domain of real-world vision and (2) to use this expanded scope to investigate basic mechanisms of vision in clinical and normal populations. Results will improve understanding of the relative importance of ocular monochromatic and chromatic aberrations for vision, the role of peripheral retinal image quality in myopia, the role of color changes in the retinal image for spatial vision, the mechanism of binocular summation of aberrated images, the importance of pupil size in outcome assessment of refractive surgery, and the nature of the eye's internal optical structure. Project 1. Expand wavefront aberrometry into the domain of polychromatic light by developing and employing a novel, trichromatic wavefront aberrometer and polychromatic metrics of optical quality. We will use these tools to quantify the effects of ocular aberrations on spatial vision, blur perception, and refraction. Project 2. Expand wavefront-based analysis of retinal image quality into the peripheral visual field in normal and myopic eyes. Using polychromatic metrics of retinal image quality, test current hypotheses that myopic eyes have reduced image quality and a larger depth-of-focus in the peripheral field, which may disrupt normal emmetropization and promote axial myopia. Project 3. Evaluate the importance of color changes in the polychromatic retinal image caused by ocular aberrations. We will seek evidence that luminance dominates spatial vision but blur sign depends on color. Project 4. Expand wavefront aberrometry into the domain of binocular vision by simulating binocular integration of dissimilar retinal images and evaluating outcome with metrics of cyclopean image quality. Project 5. Expand the dynamic range and spatial resolution of wavefront aberrometry for measuring clinically abnormal eyes. Test the hypothesis that aberrations at the pupil margin causes night vision complaints. Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight.

描述（由申请人提供）：我们的研究计划的长期目标是了解光学因素和视网膜因素如何限制视觉体验的质量。我们在下一个项目时期的具体目的是（1）将波前像素的范围扩展到现实世界视觉领域，（2）使用这种扩展的范围来研究临床和正常种群中视力的基本机制。结果将提高人们对视觉单色和色差的相对重要性的理解，周围视网膜图像质量在近视中的作用，颜色在视网膜图像中的作用变化在视网膜图像中的空间视觉，多余图像的双目总和的机制，学生大小的重要性在屈光度的结构中的重要性和内在的结构。项目1。通过开发和采用一种新颖的三色波段异差计和光学质量的多色指标，将波前像晶的异常分析扩展到多色光的结构域。我们将使用这些工具来量化眼畸变对空间视觉，模糊感和折射的影响。项目2。在正常和近视眼中，将视网膜图像质量的基于波兰的分析扩展到外围视野。使用视网膜图像质量的多色指标，测试当前的假设，即近视眼降低了图像质量和周围场中更大的聚焦，这可能会破坏正常的弹性化并促进轴向近视。项目3。评估颜色变化的重要性在由眼畸变引起的多色视网膜图像中。我们将寻求证据表明亮度主导空间视力，但模糊的符号取决于颜色。项目4。通过模拟视网膜图像的双眼整合并使用cyclepean图像质量的指标来评估结果，从而将波前像晶的异差扩展到双眼视觉领域。项目5。扩展波前像素测量值的动态范围和空间分辨率，以测量临床异常的眼睛。检验以下假设，即瞳孔边缘的畸变会导致夜视投诉。项目6。开发一个新的波前断层扫描概念，以从沿多种视线的一系列波前测量值来表征眼睛光学系统的3维结构。