The Ohio State University Comprehensive Cancer Center

俄亥俄州立大学综合癌症中心

• 批准号: 7347633
• 负责人: MICHAEL A CALIGIURI
• 金额: $ 375.37万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-12 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7347633
• 关键词: Ohio; State; University; Comprehensive; Cancer

DESCRIPTION (provided by applicant): The Ohio State University Comprehensive Cancer Center (OSUCCC) is currently in its 29th year as an NCI-designated CCC and is now requesting continued federal support for the next five years. The OSUCCC named its 4th Director, Michael A. Caligiuri, M.D. in July, 2003 while retaining the former Center Director, Clara D. Bloomfield, M.D., as a Senior Advisor to the OSUCCC. The overall goal remains to reduce cancer morbidity and mortality through continued basic, translational and clinical research. The 183 OSUCCC members are currently served by 13 shared resources and are distributed among 6 Research Programs: Cancer Control, Experimental Therapeutics, Immunology, Molecular Biology and Cancer Genetics, Molecular Carcinogenesis and Chemoprevention and Viral Oncogenesis. Since the last competitive renewal, the OSUCCC has shown significant growth as demonstrated by: 1) the recruitment of more than 90 new cancer research faculty to OSU; 2) more than a 230% increase in patient accrual to investigator-initiated trials; 3) the addition of 6 new shared resources at an institutional investment of over $10.8 M; 4) a 144% increase in total NCI funding and a 65% increase in peer-reviewed funding. The OSUCCC has also seen tremendous growth in institutional commitment since 1999 as demonstrated by: 1) a new formal role for the OSUCCC Director within OSU, providing complete oversight of the University-wide cancer funding initiatives, opportunities and cancer grant submissions; 2) A seat on the eight-member Medical Center Executive Committee which meets every week with the Senior VP of Health Sciences to plan and evaluate the entire Health System's direction (cancer is the only discipline represented on this Committee); 3) a written commitment for the expansion of the Cancer Program facilities that will result in more than a four-fold increase over the current square footage under control of the OSUCCC Director at a cost of approximately $350 M; 4) interim laboratory and office space for recruitment until the new facility is constructed; 5) an additional $7.0 M of cash annually from OSU for research and infrastructure expansion; and 6) twenty senior faculty slots under the control of the OSUCCC Director, each provided with $100,000 of guaranteed salary in perpetuity. With these new resource commitments in place, the OSUCCC is poised for significant growth and expansion in the next 5 years.

描述（由申请人提供）：俄亥俄州立大学综合癌症中心（OSUCCC）目前已成为NCI指定的CCC的第29年，目前正在为未来五年提供持续的联邦支持。 OSUCCC在2003年7月任命其第四任主任Michael A. Caligiuri，同时保留了前中心主任Clara D. Bloomfield，M.D。担任OSUCCC的高级顾问。 总体目标仍然是通过持续的基础，翻译和临床研究来降低癌症的发病率和死亡率。 目前，183个OSUCCC成员由13个共享资源提供服务，并分布在6个研究计划中：癌症控制，实验性治疗，免疫学，分子生物学和癌症遗传学，分子癌变以及化学预防以及病毒性肿瘤发生。 自上次竞争性更新以来，OSUCCC已显示出显着的增长，如：1）招募了90多名新的癌症研究教师到OSU； 2）研究人员发起的试验的患者应计增长超过230％； 3）在机构投资超过10.8 m的机构投资中增加了6个新的共享资源； 4）NCI总资金增加了144％，同行评审的资金增加了65％。 自1999年以来，OSUCCC还看到了机构承诺的巨大增长：1）OSU内OSUCCC主管的新正式角色，提供了对全大学范围的癌症资助计划，机会和癌症赠款提交的完整监督； 2）由八人组成的医疗中心执行委员会席位，每周都会与健康科学高级副总裁计划和评估整个卫生系统的方向（癌症是本委员会唯一代表的学科）； 3）对于扩大癌症计划设施的书面承诺，将导致OSUCCC董事控制的当前平方英尺增加4倍以上，费用约为350 m； 4）临时实验室和办公空间进行招聘，直到建造新设施为止； 5）每年从OSU额外获得7.0 m的现金，以进行研究和基础设施扩展； 6）在OSUCCC董事的控制下，有20个高级教师老虎机，每位董事的保证薪水永久性提供了100,000美元。 有了这些新的资源承诺，OSUCCC有望在未来5年内实现显着增长和扩张。