Research training in chronic, non-communicable respiratory diseases in Peru

秘鲁慢性非传染性呼吸道疾病研究培训

基本信息

批准号：
10210462
负责人：
William Checkley
金额：
$ 24.28万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-15 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10210462
关键词：
Address Adult Affect Altitude Automobile Driving Award Baltimore Chronic Chronic Obstructive Airway Disease Collaborations Communities Complex Coupled Discipline Doctor of Philosophy Effectiveness Environmental Exposure Environmental Health Epidemic Faculty Gender Generations Goals Grant Health Health Professional Household Air Pollution Institution International Intervention Lung Lung diseases Master&apos s Degree Mentorship National Institute of Environmental Health Sciences Occupational Peru Peruvian Policies Postdoctoral Fellow Public Health Public Health Practice Research Research Personnel Research Training Risk Risk Factors Scientist Students Tobacco smoke Training Training Programs Training and Infrastructure Translations United States National Institutes of Health Universities Woman ambient air pollution biomass fuel clinical epidemiology cohort combat cooking doctoral student efficacy trial implementation science international center low socioeconomic status programs rural residence social factors training opportunity

项目摘要

PROJECT SUMMARY Chronic pulmonary diseases coupled with environmental exposures present a growing public health problem in Peru, and globally. Indoor and outdoor air pollution, tobacco smoke and occupational fumes and exposures all contribute to burden of chronic respiratory disease in Peru. Social factors such a low socioeconomic status and gender further compound this exposure risk. For instance, in high altitude communities in the Andes, approximately 10% of adults are living with chronic obstructive pulmonary disease (COPD), affecting primarily women. Household air pollution, a major risk factor for COPD, is common in poor rural households where biomass fuels are used for cooking and accounts for over half (55%) of COPD cases in women in Peruvian highland communities. Noting these risks and increased exposure, there is an ever-growing need for research to address the causes and develop interventions to combat the environmental exposures driving the chronic pulmonary disease epidemic in Peru. This application for the NIH D43 Training Grant, a collaboration between William Checkley, MD, PhD at Johns Hopkins University in Baltimore, MD and Stella Hartinger, PhD at Universidad Peruana Cayetano Heredia in Lima, Peru, leverages 30 years of collaborations between our institutions to build a training and research program for promising, young Peruvian research scientists and health professionals. This cohort will have the opportunity to focus on environmental health and chronic pulmonary disease research with the mentorship and support of international, renowned faculty and advisors within environmental and pulmonary research, ranging from atmospheric scientists to implementation researchers. The program will provide intensive training opportunities and build training capacity in the range of scientific disciplines (clinical epidemiology, exposure assessment, efficacy trials, implementation science) relevant to addressing environmental exposure and pulmonary disease research at the masters, PhD and post-doctoral levels. The proposed training program will provide support to two doctoral students from Peru at JHBSPH and five master’s degree students at UPCH over the five-year award period and we will support five Peruvian postdoctoral fellows in their applications to the UJMT Global Fogarty Health Fellows program (JHU PD: Checkley). The long-term goal of this program is to build a sustainable and collaborative research-training infrastructure to support the generation of evidence for the effectiveness of complex interventions to address these health issues, as well as the translation of this evidence to policy and public health practice in Peru. This application is responsive to partnering institutions of PAR-18-901 including the Fogarty International Center and the National Institutes of Environmental Health Sciences through its focus on chronic pulmonary diseases and environmental exposures.

项目概要慢性肺部疾病加上环境暴露在以下地区构成了日益严重的公共卫生问题秘鲁以及全球范围内的室内和室外空气污染、烟草烟雾和职业烟雾和暴露。社会经济地位低等社会因素加重了秘鲁慢性呼吸道疾病的负担。性别进一步加剧了这种暴露风险，例如，在安第斯山脉的高海拔社区，大约 10% 的成年人患有慢性阻塞性肺病 (COPD)，主要影响家庭空气污染是慢性阻塞性肺病的一个主要危险因素，在贫困农村家庭中很常见。生物质燃料用于烹饪，占秘鲁女性慢性阻塞性肺病病例的一半以上 (55%) 注意到这些风险和增加的风险，对研究的需求不断增长。解决根源并制定干预措施，以应对导致慢性病的环境暴露秘鲁的肺部疾病流行病申请 NIH D43 培训补助金，由以下机构合作完成。巴尔的摩约翰霍普金斯大学医学博士 William Checkley 和巴尔的摩约翰霍普金斯大学医学博士 Stella Hartinger 博士位于秘鲁利马的秘鲁卡耶塔诺埃雷迪亚大学充分利用了我们之间 30 年的合作机构为有前途的年轻秘鲁研究科学家和该群体将有机会关注环境健康和慢性病。在国际知名教师和顾问的指导和支持下进行肺部疾病研究在环境和肺部研究领域，从大气科学家到实施该计划将提供强化培训机会并培养一系列的培训能力。科学学科（临床流行病学、暴露评估、功效试验、实施科学）与解决硕士、博士和博士学位的环境暴露和肺部疾病研究相关拟议的培训计划将为来自秘鲁的两名博士生提供支持。 JHBSPH 的学生和 UPCH 的五名硕士学位学生在五年的奖励期内，我们将支持五名秘鲁博士后研究员申请 UJMT 全球福格蒂健康研究员计划（约翰霍普金斯大学 PD：Checkley）该计划的长期目标是建立一个可持续和协作的环境。支持生成复杂性有效性证据的研究培训基础设施解决这些健康问题的干预措施，以及将这些证据转化为政策和公众秘鲁的健康实践此应用程序响应 PAR-18-901 的合作机构。包括福格蒂国际中心和国家环境卫生研究所科学关注慢性肺部疾病和环境暴露。