Methods Core for Study and Data Collection, Design, Support and Dissemination

研究和数据收集、设计、支持和传播的核心方法

• 批准号: 10205661
• 负责人: Benjamin Le Cook
• 金额: $ 72.71万
• 依托单位: CAMBRIDGE HEALTH ALLIANCE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10205661
• 关键词: Area; Bioinformatics; Boston; Child; Cities; Clinic; Clinical; Clinical Services; Clinical Trials; Collaborations; Communities; Comparative Effectiveness Research; Computers; Consultations; Criminal Justice; Data; Data Collection; Data Set; Domestic Violence; Early identification; Early treatment; Effectiveness; Electronic Health Record; Equation; Ethnic Origin; Evidence based practice; Family; Food; Future; Grant; Growth; Health; Health Alliance; Health Insurance Portability and Accountability Act; Health Policy; Health Services; Health education; Healthcare; Heterogeneity; Individual; Infrastructure; Internet; Intervention; Investigational Therapies; Language; Lead; Leadership; Learning; Letters; Link; Measures; Mental Health; Mental disorders; Methodology; Methods; Minority; Modeling; Neighborhoods; Pathway interactions; Patients; Pilot Projects; Police; Population; Predictive Analytics; Prevention; Psychiatry; Psychopathology; Publications; Qualitative Methods; Race; Randomized Controlled Trials; Recovery; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk; Schools; Screening procedure; Shelter facility; Structure; Students; Suicide; Symptoms; System; Techniques; Teenagers; Testing; Translations; Trauma; Vertebral column; Voice; Youth; analytical method; base; behavioral/social science; community based participatory research; comorbidity; cooking; data infrastructure; data warehouse; design; early screening; education access; effectiveness evaluation; experience; flexibility; functional disability; health care service; health data; health economics; health equity; high risk; high school; insurance claims; novel; racial and ethnic; resilience; social health determinants; statistics; symptomatology; treatment effect; volunteer

PROJECT SUMMARY/ABSTRACT - Cambridge Health Alliance ALACRITY for Early Screening and Treatment of High Risk Youth (eSToRY) Methods Core for Study and Data Collection Design, Support and Dissemination The Methods Core will be the linchpin of the eSToRY Center, bringing together a powerful mix of clinical and sociocontextual data, the latest rapid computer adaptive testing of psychopathology and symptomatology, a suite of rigorous in-depth community-engaged qualitative techniques and quantitative methods applied to large administrative and clinical trial data, and an emphasis on community-based participatory research to increase the relevance and appropriateness to racial/ethnic and language (REL)-minority youth and families. The backbone of the Methods Core is a team of renowned methodological experts and a large clinical-sociocontextual dataset, linking >600,000 REL-diverse patients' electronic health records (EHR), insurance claims, criminal justice, neighborhood- and individual-level social determinants of health (SDOH) data, and computer adaptive psychiatric testing. These merged data comprise an extensive data warehouse that will facilitate novel solutions to intractable mental health problems. In Aim 1, we will establish a HIPAA-compliant integrated clinical-sociocontextual data warehouse for use in early identification, prevention, and treatment of mental illness among REL-diverse youth. In Aim 2, we will provide methodological support to three R34 projects and pilot projects, employing the latest rigorous quantitative and qualitative methods to increase the relevance and understanding of mechanisms of racial/ethnic and language disparities in access and quality of mental health care. In Aim 3, we will engage and solicit participation of individuals from diverse backgrounds, including community stakeholders, to assure the relevance of the research projects, interpret results, develop interventions, and disseminate findings through a strong web of clinical-, school-, and community-based connections.

项目摘要/摘要 - 剑桥健康联盟 ALACRITY 用于高危青少年的早期筛查和治疗 (eSToRY) 研究和数据收集设计、支持和传播的核心方法 方法核心将成为 eSToRY 中心的关键，汇集了强大的组合 临床和社会背景数据，最新的快速计算机自适应测试 精神病理学和症状学，一套严格深入的社区参与 定性技术和定量方法应用于大型管理和临床试验 数据，并强调基于社区的参与性研究以提高相关性 以及对种族/族裔和语言 (REL) 少数群体青少年和家庭的适当性。这 方法核心的骨干是由著名的方法学专家和大量的专家组成的团队 临床社会情境数据集，链接超过 600,000 名 REL 多样化患者的电子健康 记录 (EHR)、保险索赔、刑事司法、社区和个人层面的社会 健康决定因素（SDOH）数据和计算机自适应精神病学测试。这些合并了 数据构成了一个广泛的数据仓库，它将促进针对棘手问题的新颖解决方案 心理健康问题。 在目标 1 中，我们将建立符合 HIPAA 要求的集成临床社会情境数据 用于早期识别、预防和治疗精神疾病的仓库 REL-多元化的青年。在目标 2 中，我们将为三个 R34 项目提供方法支持 试点项目，采用最新的严格的定量和定性方法来提高 对获取方面种族/族裔和语言差异机制的相关性和理解 和精神卫生保健的质量。在目标 3 中，我们将吸引并征求个人的参与 来自不同背景，包括社区利益相关者，以确保项目的相关性 研究项目、解释结果、制定干预措施并通过 强大的临床、学校和社区联系网络。