PATHOLOGY CORE FACILITY

病理学核心设施

• 批准号: 7610468
• 负责人: WILLIAM JM HRUSHESKY
• 金额: $ 8.53万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610468
• 关键词: Carcinoma; Cells; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Funding; Genetic; Grant; Hyperplasia; Infiltration; Inflammatory; Institution; Intervention; Mus; Normal tissue morphology; Pathology; Research; Research Personnel; Resources; Source; Structure; Tissues; United States National Institutes of Health; adenoma; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Pathology Core. [William Hrushesky, Director] The Pathology Core provides detailed pathological characterization of both tumors and normal tissues in wild-type and ApcMin/+ mice. Morphological aberrations in tissues resulting from genetic, pharmacological, dietary, or other interventions are characterized. Tumors are classified with regard to overall structure (polypoid, flat, hyperplastic, dysplastic), degree of invasiveness (adenoma, carcinoma), extent of inflammatory cell infiltration, and other parameters.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 病理学核心。 [William Hrushesky，主任] 病理学核心提供了野生型和 ApcMin/+ 小鼠肿瘤和正常组织的详细病理特征。 表征由遗传、药理学、饮食或其他干预措施引起的组织形态畸变。 肿瘤根据总体结构（息肉样、扁平、增生、发育不良）、侵袭程度（腺瘤、癌）、炎性细胞浸润程度和其他参数进行分类。