Center to Advance Research Excellence (OPTIC) Center to Advance Research Excellence (OPTIC).

卓越研究推进中心 (OPTIC) 卓越研究推进中心 (OPTIC)。

• 批准号: 9919033
• 负责人: BRADLEY D STEIN
• 金额: $ 11.38万
• 依托单位: RAND CORPORATION
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9919033
• 关键词: Address; Adopted; Advocate; Affect; Area; Awareness; Buprenorphine; Characteristics; Communication; Communication Methods; Communities; Complex; Data; Data Sources; Databases; Development; Dimensions; Documentation; Educational workshop; Effectiveness; Elements; Emergency response; Fostering; General Population; Geography; Healthcare; Individual; Joints; Law Enforcement; Lead; Leadership; Light; Marketing; Measures; Methodology; Methods; Modeling; Monitor; Nature; Opioid; Opioid Analgesics; Overdose; Pain management; Persons; Pharmaceutical Preparations; Pharmacologic Substance; Police; Policies; Policy Analysis; Policy Research; Privatization; Public Health; Recovery; Research; Research Personnel; Resources; Rural Community; Services; Speed; Standardization; Substance abuse problem; Time; TimeLine; Training; Work; analytical method; community center; data resource; data warehouse; design; education resources; experience; illicit opioid; innovation; models and simulation; opioid epidemic; opioid overdose; opioid policy; opioid use; opioid use disorder; prescription monitoring program; prescription opioid; relative effectiveness; response; simulation; skills; societal costs; stem; tool; waiver; web site

ABSTRACT The U.S. is in the midst of an opioid crisis, and efforts to tackle the complex and dynamic nature of this public health challenge must comprehensively consider a multitude of contributing factors. States have implemented a wide range policies and initiatives in response. However, the dynamic nature of the crisis and speed with which different policy approaches are being implemented pose numerous challenges for researchers evaluating the effects of such efforts. These challenges stem in part from limited information regarding policy implementation, insufficient information about policy characteristics that may influence effectiveness, little consideration of how the chosen analytic method may influence findings given simultaneous or concurrent implementation of multiple policies, and limited training on how to best communicate findings to policymakers. To address these challenges, the proposed Center for Opioid Policy Research (COPR) will serve as a national resource, fostering innovative and high-quality research in the opioid policy arena and developing and disseminating methods, tools, and information to the research community, policymakers, and the general public. Leveraging the extensive experience of COPR leadership and our External Advisory Board, COPR will create resources of significant value to those working in this policy domain. We will develop a state-level opioid policy database, accessible to both researchers and policymakers, that assembles comprehensive opioid policy information from a variety of domains (e.g., health care, pharmaceuticals, law enforcement) into a single standardized data resource that offers detailed timelines of various policies and groups of policies within each state. Drawing from this resource, we will conduct detailed assessments and documentation of new and emerging policy dimensions for which we can provide robust scientific support demonstrating causal effects. Through the Center’s access to multiple, complementary secondary data sources that capture a broad range of measures relevant to both licit and illicit opioids, we will develop new metrics of local opioid markets that can be used to evaluate or monitor impacts of policies in local areas. Finally, we will use simulation methods to design a simulation platform to develop robust new methods for identifying the joint impact of multiple, co- occurring polices. To enhance awareness and use of COPR findings and foster effective communication with policymakers and the broader research community, COPR will rely upon a multipronged dissemination and educational approach. The Center website will provide a comprehensive data repository and rich resources on state-of-the-art methods and metrics. In-person and online communication and methods workshops will highlight key Center project findings and provide training on how best to communicate research with nontechnical audiences. Finally, a strategic marketing campaign will raise visibility of the Center’s data, research and educational resources among substance abuse researchers and policymakers.

抽象的 美国正处于阿片类药物危机之中，并努力解决这一公众的复杂性和动态性 健康挑战必须综合考虑各国已实施的多种促成因素。 采取广泛的政策和举措来应对 然而，危机的动态性和速度也随之变化。 正在实施哪些不同的政策方法给研究人员带来了许多挑战 评估这些努力的效果的部分原因是有关政策的信息有限。 实施方面，有关可能影响有效性的政策特征的信息不足，很少 考虑所选分析方法如何影响同时或同时给出的结果 实施多项政策，并且关于如何最好地向政策制定者传达调查结果的培训有限。 为了应对这些挑战，拟议的阿片类药物政策研究中心 (COPR) 将作为国家 资源，促进阿片类药物政策领域的创新和高质量研究，并开发和 向研究界、政策制定者和公众传播方法、工具和信息 利用 COPR 领导层和外部顾问委员会的丰富经验，COPR 将 我们将开发一种国家级阿片类药物，为该政策领域的工作人员创造重要价值的资源。 研究人员和政策制定者均可访问的政策数据库，汇集了全面的阿片类药物 将来自各个领域（例如医疗保健、制药、执法）的政策信息整合到一个单一的 标准化数据资源，提供各种政策和每个政策组内的政策的详细时间表 利用该资源，我们将对新的和新的资源进行详细的评估和记录。 我们可以为新兴的政策维度提供强有力的科学支持，证明其因果效应。 通过该中心访问多个互补的二手数据源，这些数据源捕获了广泛的 与合法和非法阿片类药物相关的措施，我们将制定当地阿片类药物市场的新指标， 最后，我们将使用模拟方法来评估或监测政策对当地的影响。 设计一个模拟平台来开发强大的新方法来识别多个共同影响的联合影响 提高对 COPR 调查结果的认识和使用，并促进与各方的有效沟通。 COPR 将依赖于政策制定者和更广泛的研究界的多管齐下的传播和 该中心网站将提供全面的数据存储库和丰富的资源。 最先进的方法和指标将进行面对面和在线交流和方法研讨会。 突出中心项目的关键发现，并提供有关如何最好地与研究人员交流研究的培训 最后，战略营销活动将提高该中心数据的知名度， 药物滥用研究人员和政策制定者的研究和教育资源。