The Opioid Crisis: The Effects and Unintended Consequences of State Policies on Opioid Analgesic Prescribing

阿片类药物危机：国家政策对阿片类药物镇痛处方的影响和意外后果

基本信息

批准号：
10312797
负责人：
BRADLEY D STEIN
金额：
$ 63.18万
依托单位：
RAND CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-03-15 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10312797
关键词：
Address Admission activity Affect Behavior Characteristics Clinical Communities County Coupled Data Data Set Data Sources Diagnosis Disabled Persons Disadvantaged Drug Insurance Drug Utilization Health Individual Literature Medical Medicare Medicare claim Mental Health Monitor Oncology Operative Surgical Procedures Opioid Opioid Analgesics Outcome Overdose Pain Clinics Pain management Patients Pattern Pharmaceutical Preparations Pharmacy facility Policies Population Public Health Recording of previous events Regulation Risk Rural Rural Community Societies Substance Use Disorder Therapeutic Touch sensation Variant beneficiary design ethnic minority ethnic minority population experience federal policy high risk population opioid abuse opioid epidemic opioid misuse opioid mortality opioid overdose opioid use patient population practice setting prescription drug abuse prescription monitoring program prescription opioid prescription pain reliever prior authorization programs racial and ethnic response rural area socioeconomic disadvantage surgical pain

项目摘要

Project Summary The U.S. is facing an opioid-related public health crisis, and states have responded with a range of policies and initiatives, many of which are intended to decrease the widespread availability of opioid analgesics. Our understanding of the impact of these policies is still evolving, results of studies have been mixed, and no studies have examined to what extent policies have decreased potentially inappropriate prescribing while leaving likely appropriate prescribing untouched. To assess the impact of state policies and initiatives on overall opioid prescribing rates, likely appropriate prescribing, and potentially inappropriate prescribing, this project will produce empirical findings addressing these gaps using Medicare claims data for disabled beneficiaries, as well as IQVIA data which covers an estimated 88% of prescriptions filled at U.S. pharmacies. It will also examine how policies affect opioid prescription fills for historically underserved and high-risk populations. The results will inform state policymaking efforts related to the opioid crisis.

项目概要美国正面临与阿片类药物相关的公共卫生危机，各州已采取一系列政策和措施予以应对举措，其中许多举措旨在减少阿片类镇痛药的广泛使用。我们的对这些政策影响的理解仍在不断发展，研究结果好坏参半，并且没有研究考察了政策在多大程度上减少了潜在的不当处方，同时保持可能的适当处方不变。评估国家政策和举措的影响总体阿片类药物处方率、可能适当的处方和可能不适当的处方，这项目将利用残疾人医疗保险索赔数据得出实证结果来解决这些差距受益人，以及 IQVIA 数据，该数据覆盖了美国药房约 88% 的处方。它还将研究政策如何影响历史上服务不足和高风险的阿片类药物处方药人口。研究结果将为与阿片类药物危机相关的国家政策制定工作提供信息。

项目成果

期刊论文数量（2）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Urine drug testing in the context of opioid analgesic prescribing for chronic pain: a content analysis of U.S. state laws in 2022.

慢性疼痛阿片类镇痛处方背景下的尿液药物检测：2022 年美国各州法律的内容分析。

DOI：
发表时间：
2023-12-01
期刊：
影响因子：
0
作者：
Andraka;McAvoy, Elizabeth;Gordon, Adam J;Ohama, Maggie;Brach, Marilyn;Taylor, Erin A;Vaiana, Mary;Saloner, Brendan;Stein, Bradley D
通讯作者：
Stein, Bradley D

A National Retrospective Study of Antidepressants' Effects on Overdose and Self-Harm Among Adults Treated With Opioid Analgesics.

一项关于抗抑郁药对接受阿片类镇痛药治疗的成年人服用过量和自我伤害的影响的全国回顾性研究。

DOI：
发表时间：
2023-01-01
期刊：
影响因子：
0
作者：
Sherry, Tisamarie B;Nguyen, Thuy;Dick, Andrew W;Bradford, Ashley C;Simon, Kosali;Stein, Bradley D
通讯作者：
Stein, Bradley D