17 ALPHA-HYDROXYPROGESTERONE CAPROATE (17-HPC) FOR PREVENTION OF PRETERM LABOR

17 α-羟基孕酮己酸酯 (17-HPC) 用于预防早产

• 批准号: 7608487
• 负责人: Henry Yeager
• 金额: $ 1.76万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608487
• 关键词: Blood; CRH gene; Computer Retrieval of Information on Scientific Projects Database; Corticotropin-Releasing Hormone; Funding; Grant; Hydroxyprogesterone Caproate; Institution; Monitor; Patients; Peptides; Pharmaceutical Preparations; Premature Birth; Premature Labor; Prevention; Purpose; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Work; steroid hormone; tandem mass spectrometry

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study is to compare blood levels in patients receiving 17-alpha hydroxyprogesterone caproate (17-HPC) for the prevention of preterm delivery to those who are not, in order to help understand the mechanisms by which the drug works. In particular, we are looking at CRH peptide and other steroid hormones. Analysis of blood levels will be performed using tandem mass spectrometry. The information hopefully will be used to support a larger NIH funded study, and will help target and monitor therapy using 17-HPC.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该研究的目的是比较接受17-α-羟孕酮的患者的血液水平（17-HPC），以预防早产与那些没有早产的患者，以帮助了解药物的作用。 特别是，我们正在研究CRH肽和其他类固醇激素。 血液水平的分析将使用串联质谱法进行。 希望该信息将用于支持大型NIH资助的研究，并将使用17-HPC帮助和监测治疗。