PPAR MEDICATED GENE EXPRESSION IN HIV PATIENTS

HIV 患者中 PPAR 药物基因表达

• 批准号: 7607876
• 负责人: MARIE C GELATO
• 金额: $ 69.58万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-23 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607876
• 关键词: Abdomen; Affect; Cholesterol; Computer Retrieval of Information on Scientific Projects Database; Diabetes Mellitus; Disease; Drug usage; Fatty acid glycerol esters; Funding; Gene Expression; Grant; HIV; Institution; Leg; Liver; Muscle; Patients; Purpose; Research; Research Personnel; Resources; Source; Tissues; Triglycerides; United States National Institutes of Health; Upper arm

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to understand how muscle, fat and liver tissue are being affected by drugs used to treat patients with HIV disease. This is important because patients with HIV disease may develop abnormal fat distribution (thin arms and legs, fat abdomen), diabetes mellitus and increased cholesterol and triglycerides. This is called lypodystrophy.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是了解肌肉，脂肪和肝组织如何受到用于治疗HIV疾病患者的药物的影响。这很重要，因为艾滋病毒疾病患者可能会出现异常的脂肪分布（薄臂和腿部，脂肪腹部），糖尿病，胆固醇和甘油三酸酯增加。这称为脂肪营养不良。