NUCLEOSIDE TRANSPORTERS

核苷转运蛋白

• 批准号: 7607631
• 负责人: CHOUKRI BEN MAMOUN
• 金额: $ 0.41万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607631
• 关键词: Affect; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Condition; Disease; Erythrocytes; Eye; Funding; Future; Goals; Grant; Human; Institution; Malaria; Molecular; Nucleoside Transporter; Parasites; Pathway interactions; Pharmaceutical Preparations; Plasmodium; Population; Purpose; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Vaccines; drug development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Malaria, a disease caused by protozaon parasites of the genus Plasmodium, is one of the most dangerous infectious disease affecting human populations. The purpose of this research is to determine the conditions that help the multiplication of the parasite in human red blood cells. The scientific information received from this study may help understand the disease and identify new drugs or a vaccine against malaria. Research in the Lab will focus on how the Human Malaria Parasite develops within human red blood cells. Our goal is to characterize, at the molecular level, the pathways essential for the parasite survival with an eye toward future drug development.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 疟疾是一种由疟原虫属原虫寄生虫引起的疾病，是影响人类的最危险的传染病之一。这项研究的目的是确定有助于寄生虫在人类红细胞中繁殖的条件。从这项研究中获得的科学信息可能有助于了解这种疾病并确定抗疟疾的新药或疫苗。 实验室的研究将集中于人类疟疾寄生虫如何在人类红细胞内发育。我们的目标是在分子水平上表征寄生虫生存所必需的途径，并着眼于未来的药物开发。