LYSOSOMES IN ATHERSCLEROSIS

动脉粥样硬化中的溶酶体

• 批准号: 7605670
• 负责人: WALTER G JEROME
• 金额: $ 0.1万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7605670
• 关键词: Acids; Cells; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Lysosomes; Membrane; Property; Research; Research Personnel; Resources; Source; Sterols; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We hypothesist hat "in cells with lysosomal sterol accumulation, the FC accummulation alters lysosomal membrane properties in ways that inhibit the ability of lysosomes to mainitain an acid pH".

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们假设存在溶酶体固醇积累的细胞中的帽子，FC的差异以抑制溶酶体对脂肪蛋白酶酸pH pH的能力的方式改变了溶酶体膜的性能”。