USF Scholars in Patient-Oriented Research (SPOR)

南佛罗里达大学以患者为导向的研究学者 (SPOR)

• 批准号: 7673718
• 负责人: Kenneth S. Zuckerman
• 金额: $ 30万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7673718
• 关键词: Bioinformatics; Biometry; Cellular biology; Clinical; Clinical Pharmacology; Clinical Research; Clinical Trials Design; Comprehensive Cancer Center; Deer; Educational Curriculum; Educational process of instructing; Epidemiologic Studies; Evaluation; Faculty; Fellowship; Florida; Funding; Goals; Grant; Health Sciences; Industry; Informatics; Institution; Investigator-Initiated Research; Lead; Manuscripts; Master' s Degree; Mentors; Metabolism; Molecular; Molecular Biology; NCI-Designated Cancer Center; Occupations; Online Systems; Outcome; Peer Review; Pharmacology; Phase; Physiology; Positioning Attribute; Process; Process Assessment; Professional Ethics; Publications; Research; Research Personnel; Research Project Grants; Research Training; SECTM1 gene; Therapeutic; Therapeutic Clinical Trial; Training; Training Programs; Translational Research; Universities; Writing; abstracting; base; design; human disease; member; patient oriented research; population based; programs

This is a proposal is for a Scholars in Patient-Oriented Research (SPOR) Program at the University of South Florida '_(USF). USF has made major strides over the past decade toward the goal of becoming a major research university increasing external research funding from less than $25M to nearly $250M annually. Over half of this funding is in the Health Sciences Center (HSC). About half of this funding currently is from industry-sponsored clinical therapeutic trials, and with the other half of the funding is for investigator-initiated research. Thus, it is a priority of the USF HSC to concentrate on developing a strong cadre of faculty members with expertise in patient-oriented research that is capable of receiving peer-reviewed external funding, in addition, we have a clear need to upgrade the subspecialty fellowship training programs to train increasing numbers of subspeciaity fellows to become academic clinical and translational researchers. The K30 grant is an ideal mechanism for jumpstarting these efforts. Fortunately, within our institution the Moffitt Cancer Center, an NCI-designated Comprehensive Cancer Center, has done an outstanding job of building a clinical research program, a clinical and translational research mentoring program for junior faculty, and a NCI K12- funded Clinical and Translational Research Training program. The proposed program will utilize the expertise developed at Moffitt, as well as many of the smaller foci of clinical research expertise at USF, to train junior faculty and fellows. The SPOR Program will lead to a Masters degree. It will consist of a core of classroom and web-based didactic teaching and a mentored clinical research project. Many of the courses already exist, and others will be derived from current courses, whereas some courses will be designed specifically for SPOR Program trainees. Required courses will include research and professional ethics; grantsmanship; scientific writing; diversity in clinical research; principles of cell biology, physiology, pharmacology, and molecular biology; biostatistics and informatics; fundamentals of successful patient-oriented research. There will be three tracks available: therapeutic clinical researchers (clinical trial design; Phase !/11clinical trial design, conduct, analysis and funding), population-based research (epidemiology and trial design), mechanisms of human disease (molecular basis of metabolism, clinical pharmacology, bioinformatics). A thesis or peer-reviewed publication(s) based on mentored research will be required. The executive committee will oversee the Program and will have subcommittees for (1) trainee selection, (2) mentor selection (3) curriculum (4) evaluation processes; and (5) overall SPOR Program progress. Process assessment will be based on evaluations of courses, mentored research, and the Program overall. The major long-term outcomes evaluated will include the number of trainees in academic positions, trainees doing productive clinical research (manuscripts and abstracts), and trainees with national Deer-review funded clinical and translational research Droqrams.

这是针对南佛罗里达大学以患者为导向研究（SPOR）计划的学者的建议 _（USF）。在过去的十年中，USF取得了重大进步 每年将外部研究资金从不到2500万美元增加到近2.5亿美元。超过一半的资金在 健康科学中心（HSC）。目前约有一半的资金来自行业赞助的临床治疗试验， 与研究人员发起的研究相比，另一半是资金。因此，这是USF HSC的优先事项 专注于发展有能力的患者研究方面具有专业知识的教职员工干部 通过接受同行评审的外部资金，我们显然需要升级亚科奖学金 培训计划，以培训越来越多的亚种族研究员成为学术临床和翻译 研究人员。 K30赠款是启动这些努力的理想机制。幸运的是，在我们的机构中 NCI指定的综合癌症中心Moffitt癌症中心在建造A 临床研究计划，一项针对初级教师的临床和转化研究指导计划和NCI K12- 资助的临床和转化研究培训计划。拟议的计划将利用专业知识 在莫菲特（Moffitt）以及USF临床研究专业知识的许多较小的焦点，以培训初级教师和 研究员。 SPOR计划将导致硕士学位。它将由课堂和基于网络的教学核心组成 教学和指导的临床研究项目。许多课程已经存在，其他课程将来自 当前课程，而某些课程将专门为SPOR程序学员设计。必需的课程将 包括研究和职业道德；授予技巧；科学写作；临床研究的多样性；细胞原理 生物学，生理学，药理学和分子生物学；生物统计学和信息学；成功的基础 面向患者的研究。将有三个曲目：治疗性临床研究人员（临床试验设计； 阶段！/11临床试验设计，行为，分析和资金），基于人群的研究（流行病学和试验 设计），人类疾病的机制（代谢的分子基础，临床药理学，生物信息学）。论文 或需要基于指导研究的同行评审出版物。执行委员会将监督 计划，并将具有（1）培训人员选择的小组委员会，（2）导师选择（3）课程（4）评估 过程； （5）总体传播计划进度。过程评估将基于对课程的评估， 指导的研究和整个计划。评估的主要长期结果将包括 学术职位的学员，受训人员从事富有成效的临床研究（手稿和摘要）和受训者 国家鹿评论资助了临床和翻译研究。

项目成果

EFFECTS OF THE GENIUM KNEE SYSTEM ON FUNCTIONAL LEVEL, STAIR AMBULATION, PERCEPTIVE AND ECONOMIC OUTCOMES IN TRANSFEMORAL AMPUTEES.

• DOI: 10.21300/18.2-3.2016.139
• 发表时间: 2016-09
• 期刊: Technology and innovation
• 影响因子: 0.5
• 作者: Highsmith MJ;Kahle JT;Wernke MM;Carey SL;Miro RM;Lura DJ;Sutton BS
• 通讯作者: Sutton BS

BIOENERGETIC DIFFERENCES DURING WALKING AND RUNNING IN TRANSFEMORAL AMPUTEE RUNNERS USING ARTICULATING AND NON-ARTICULATING KNEE PROSTHESES.

• DOI: 10.21300/18.2-3.2016.159
• 发表时间: 2016-09
• 期刊: Technology and innovation
• 影响因子: 0.5
• 作者: Highsmith MJ;Kahle JT;Miro RM;Mengelkoch LJ
• 通讯作者: Mengelkoch LJ

RADIOGRAPHIC ASSESSMENT OF EXTREMITY OSSEOINTEGRATION FOR THE AMPUTEE.

• DOI: 10.21300/18.2-3.2016.211
• 发表时间: 2016-09
• 期刊: Technology and innovation
• 影响因子: 0.5
• 作者: Al Muderis M;Bosley BA;Florschutz AV;Lunseth PA;Klenow TD;Highsmith MJ;Kahle JT
• 通讯作者: Kahle JT

PLAY HANDS PROTECTIVE GLOVES: TECHNICAL NOTE ON DESIGN AND CONCEPT.

玩手防护手套：设计和概念技术说明。

• DOI: 10.21300/18.2-3.2016.207
• 发表时间: 2016
• 期刊: Technology and innovation
• 影响因子: 0.5
• 作者: Houston-Hicks,Michele;Lura,DerekJ;Highsmith,MJason
• 通讯作者: Highsmith,MJason

EFFECTS OF THE GENIUM MICROPROCESSOR KNEE SYSTEM ON KNEE MOMENT SYMMETRY DURING HILL WALKING.

Genium 微处理器膝关节系统对山地行走期间膝关节力矩对称性的影响。

• DOI: 10.21300/18.2-3.2016.151
• 发表时间: 2016
• 期刊: Technology and innovation
• 影响因子: 0.5
• 作者: Highsmith,MJason;Klenow,TylerD;Kahle,JasonT;Wernke,MatthewM;Carey,StephanieL;Miro,RebeccaM;Lura,DerekJ
• 通讯作者: Lura,DerekJ