OPTICAL IMAGING FACILITY

光学成像设备

• 批准号: 7715320
• 负责人: PRISCILA SANABRIA
• 金额: $ 13.26万
• 依托单位: UNIVERSIDAD CENTRAL DEL CARIBE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715320
• 关键词: Calcium Signaling; Cells; Collaborations; Computer Retrieval of Information on Scientific Projects Database; Data; Data Quality; Environment; Equipment; Faculty; Funding; Grant; Image; Institution; Journals; Laboratories; Life; Maintenance; Microscope; Molecular Biology; Participant; Peer Review; Process; Productivity; Publications; Publishing; Research; Research Infrastructure; Research Personnel; Resolution; Resources; Source; Specimen; System; Time; Training; United States National Institutes of Health; base; cellular imaging; falls; fluorescence imaging; immunocytochemistry; innovation; instrument; optical imaging; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Optical Imaging Facility (OIF) was established at UCC during the fall of 1999. Our first major equipment has enabled researchers to assess cellular responses such as calcium signaling with fast temporal and spatial resolutions. Funds requested under this proposal have been utilized to provide technical support for this time-lapsed cell imaging system and the maintenance of its sophisticated equipment. Funds were also requested to support the integration of an immunocytochemistry laboratory into the OIF. The immunocytochemistry laboratory has provided support and continues to be an important infrastructure to produce high quality data that has been published in peer-reviewed journals. In 2007, thanks to RCMI supplemental funds, the OIF expanded its offering through the acquisition of a Confocal Microscope. The current aims of the OIF are: 1. To provide technical support to perform immunocytochemistry, quantitative fluorescence imaging capture and analysis. 2. To provide instrument access and training on the effective utilization of microscope-based equipment to carry on image capture and processing from live and fixed specimens. 3. To enhance UCC's scientific environment by providing access and support to young faculty to obtain preliminary data, helping established investigators to innovate their research and increase their publication record and enhance collaboration by organizing interactions among the facility users. The continued support of the Optical Imaging Facility has been an asset to the Cell and Molecular Biology Center since it has contributed to enhance the productivity of its current participants and constitutes a primary and attractive research resource for potential new investigators.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 光学成像设施（OIF）是在1999年秋天在UCC建立的。我们的第一个主要设备使研究人员能够评估细胞反应，例如具有快速的时间和空间分辨率的钙信号传导。 根据该提案要求的资金已被用于为该时间贴上的单元成像系统提供技术支持，并维护其复杂的设备。还要求资金支持将免疫细胞化学实验室整合到OIF中。 免疫细胞化学实验室已提供了支持，并继续是产生高质量数据的重要基础设施，该数据已在同行评审期刊上发表。在2007年，由于RCMI补充基金，OIF通过获得共聚焦显微镜扩大了其产品。 OIF目前的目标是： 1。提供技术支持以执行免疫细胞化学，定量荧光成像捕获和分析。 2。提供有关有效利用基于显微镜的设备的仪器访问和培训，以进行现场和固定标本的图像捕获和处理。 3。通过向年轻教师提供访问和支持以获取初步数据，以增强UCC的科学环境，帮助建立的研究人员通过组织设施使用者之间的互动来创新研究并增加其出版记录并增强协作。 光学成像设施的持续支持一直是细胞和分子生物学中心的资产，因为它有助于提高其当前参与者的生产率，并构成了潜在新研究人员的主要且有吸引力的研究资源。