Capacity Development Core

能力发展核心

基本信息

批准号：
10762289
负责人：
ERNEST MARTINEZ
金额：
$ 19.61万
依托单位：
UNIVERSITY OF CALIFORNIA RIVERSIDE
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-22 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10762289
关键词：
Award Basic Science California Cancer Center Planning Grant City of Hope Comprehensive Cancer Center Clinical Trials Collaborations Comprehensive Cancer Center Development Disparity Engineering Evaluation Funding Genomics Goals Grant Institution Instruction Joints Mentors Mentorship Monitor Pharmaceutical Preparations Pilot Projects Qualifying Research Research Personnel Resource Development Resources Schedule Structure Tissue Banks Translational Research United States National Institutes of Health Universities Writing drug development education research experience medical schools meetings success translational impact

Award Basic Science California Cancer Center Planning Grant City of Hope Comprehensive Cancer Center Clinical Trials Collaborations Comprehensive Cancer Center Development Disparity Engineering Evaluation Funding Genomics Goals Grant Institution Instruction Joints Mentors Mentorship Monitor Pharmaceutical Preparations Pilot Projects Qualifying Research Research Personnel Resource Development Resources Schedule Structure Tissue Banks Translational Research United States National Institutes of Health Universities Writing drug development education research experience medical schools meetings success translational impact

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项目摘要

It is challenging to build successful research collaborations. Successful collaborations are even more challenging when working across institutions and with early-stage investigators (ESIs). To overcome these challenges, we developed the Capacity Building Core. The Core's goal is to provide resources and mentorship to build joint collaborations between City of Hope Comprehensive Cancer Center (CoHCCC) and University of California, Riverside (UCR) ESI. We aim to build collaborations that 1) increase UCR capacity for drug development capacity - at all stages of the drug-develop pipeline and 2) result in independent NIH-funding. The Capacity Core will match UCR ESIs with senior CoHCCC and UCR investigators. Senior CoHCCC investigators will be selected based on their prior proven ability to 1) successfully mentor ESIs and 2) help them attain independent NIH funding. U54 PI, Drs. Ernest Martinez (UCR) and Victoria Seewaldt (CoH) have extensive mentorship experience and will lead the Capacity Core. Under the Capacity Core, UCR-CoH Mini-Pilots will be 1) crafted by ESIs under senior mentorship, 2) competed, and 3) teams awarded $100,000 for one year. Our P20 planning grant shows us that success of a pilot project is increased when ESI have senior mentors from both CoH and UCR; therefore UCR ESI applying for Mini-Pilots are required to have a CoH and UCR mentor. In Years 1 and 2 a total of 3 Mini-Pilots will be funded/year. These 6 Mini-Pilots will be an important opportunity for us to build joint UCR ESI-CoH grants and capacity at UCR. In Years 3-5, $200,000 originally allocate to the Capacity Building Core, will be re-allocated to support two new Pilots – Pilots 3 and 4. In Years 3-5, we will offer 1 Mini- Pilot/year. CoH discretionary funds ($100,000/year) will allow us to either supplement Pilot Projects or increase the number of Mini-Pilots offered in Years 3-5.

建立成功的研究合作是挑战者。成功的合作甚至更挑战跨机构和早期研究人员（ESI）工作时。为了克服这些挑战，我们开发了能力建筑核心。核心的目标是提供建立共同的资源和精通资源希望城市综合癌症中心（COHCCC）与加利福尼亚大学之间的合作河滨（UCR）ESI。我们旨在建立合作，以提高UCR药物开发能力容量 - 在药物开发管道的所有阶段，2）独立的NIH资金。容量核心将与高级COHCCC和UCR调查人员相匹配。高级COHCCC调查人员将根据他们先前的证明能力选择1）成功的心理ESI和2）帮助他们独立地获得独立 NIH资金。 U54 pi，博士。 Ernest Martinez（UCR）和Victoria Seewaldt（COH）具有广泛的心态经验并将领导能力核心。在容量核心下，UCR-COH迷你活机将是1）在高级心态下的ESI，2）参加比赛，3）团队获得了100,000美元的一年。我们的P20计划格兰特（Grant）向我们表明，当ESI拥有COH和 ucr;因此，申请迷你学生的UCR ESI必须具有COH和UCR心理。在1年和 2总共3个迷你学生将获得/年。这6个迷你学生将是我们建造的重要机会联合UCR ESI-COH赠款和UCR的容量。在3 - 5年内，$ 200,000最初分配给能力建筑核心将重新分配以支持两名新飞行员 - 飞行员3和4。在3 - 5年内，我们将提供1个小型飞行员飞行员/年。 COH Distionary Funds（每年$ 100,000）将使我们可以补充试点项目或增加 3 - 5年内提供的迷你巡回赛数量。