Administrative Core

行政核心

• 批准号: 10762288
• 负责人: ERNEST MARTINEZ
• 金额: $ 23.53万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-22 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10762288
• 关键词: Address; Advocate; Antelopes; California; Catchment Area; Cellular biology; City of Hope Comprehensive Cancer Center; Clinical; Clinical Trials; Collaborations; Communication; Communities; Community Outreach; Comprehensive Cancer Center; County; Data; Development; Disparity; Doctor of Medicine; Doctor of Philosophy; Economics; Ensure; Environment; Evaluation; Farm; Fostering; Funding; Grant; Growth; Incubators; Individual; Latina; Lead; Leadership; Los Angeles; Mentors; Mentorship; Mission; Monitor; National Cancer Institute; Neighborhoods; New York City; Pilot Projects; Policies; Policy Developments; Politics; Principal Investigator; Publications; Reporting; Research; Research Personnel; Resources; Safety; Science; Therapeutic; Time; Toxicology; Training; Translational Research; United States; United States National Institutes of Health; Universities; Work; cancer health disparity; career; chimeric antigen receptor T cells; disparity elimination; diversity and inclusion; drug development; education research; experience; frontier; health disparity; human subject protection; meetings; member; minority communities; next generation; outreach; professor; programs; rural area; timeline

The Administrative Core is led by the U54’s Principal Investigators, Ernest Martinez, Ph.D. (PI, University of California, Riverside [UCR]) and Victoria Seewaldt, M.D. (PI, City of Hope Comprehensive Cancer Center [CoHCCC]). The overall mission of the Administrative Core is to facilitate the U54 UCR – CoH Comprehensive Cancer Center (CoHCCC) U54 partnership by providing high-quality scientific leadership, administrative support, and fiscal management. The Administrative core supports U54 planning, priority-setting, and implementation. The Core will support the ability of the External Advisory Board (EAB), Internal Advisory Board (IAB), and Community Advisory Board (CAB) to guide and provide advice and oversight of our U54. Our EAB members are national leaders and lead their own P20 and U54 grants focusing on eliminating disparities. EAB leaders include Robert Winn, M.D. (Massey Comprehensive Cancer Center), Laura Fejerman, Ph.D. (UC Davis), Lucio Miele, M.D. (LSU), and Melissa Simon, Ph.D. (Lurie Comprehensive Cancer Center). Our IAB members are senior leaders at both UCR and CoHCCC. IAB leaders from UCR include Dr. Kelechi Kalu, Ph.D. and Vice Provost and Professor of Political Science; Dr. Frances Sladek, Professor of Cell Biology and Toxicology. IAB leaders from CoHCCC include Steven Forman, Ph.D., CoHCCC leader of CAR-T cell therapeutics program and Beckman Therapeutic Director; Linda Malkas, Ph.D., Dean of Translational Science and External Affairs. To ensure mentorship of the next generation of U54 leaders, we include on our IAB, two early-stage investigators (ESIs) serve on our IAB, this includes Jernej Murn, Ph.D., a basic investigator from UCR and Ana Tergas, M.D., a promising clinical trialist and Latina researcher from CoHCCC. Together, we will work with the Planning and Evaluation Core (PEC) and serve as the U54’s oversight body. The IAB will meet with U54 leaders twice-year - or more frequently if needed - to provide strategic direction, policy development, and evaluation of our U54 Partnership Projects and Cores. The PEC, IAB, and EAB will perform yearly review of Full and Pilot projects and Cores. The CAB will evaluate projects and cores – particularly our Community Outreach Core and assess our ability to mentor and promote the careers of URM ESI. The EAB, IAB, and CAB will meet jointly with U54 project and core leaders to assess overall progress and ability to impact cancer health disparities and disparities in drug development and clinical trials.

行政核心由 U54 的首席研究员 Ernest Martinez 博士（PI，美国大学）领导。 加利福尼亚州河滨 [UCR]）和 Victoria Seewaldt，医学博士（PI，希望之城综合癌症中心） [CoHCCC]) 行政核心的总体使命是促进 U54 UCR – CoH 综合 癌症中心 (CoHCCC) U54 通过提供高质量的科学领导、行政支持、 行政核心支持 U54 规划、优先事项设定和实施。 该核心将支持外部顾问委员会 (EAB)、内部顾问委员会 (IAB) 和 社区咨询委员会 (CAB) 为我们的 U54 提供指导、建议和监督。 国家领导人并领导他们自己的 P20 和 U54 赠款，重点关注消除差距 EAB 领导人包括。 Robert Winn，医学博士（梅西综合癌症中心）、Laura Fejerman，博士（加州大学戴维斯分校）、Lucio Miele， M.D.（路易斯安那州立大学）和 Melissa Simon 博士（Lurie 综合癌症中心）是我们的 IAB 高级成员。 UCR 和 CoHCCC 的领导者包括 Kelechi Kalu 博士和副教务长 政治学教授；Frances Sladek 博士，IAB 细胞生物学和毒理学教授。 CoHCCC 包括 CAR-T 细胞治疗项目 CoHCCC 负责人 Steven Forman 博士和 Beckman 治疗主任；Linda Malkas 博士，转化科学与对外事务部院长。 对下一代 U54 领导人的指导，我们的 IAB 中包括两名早期研究人员 (ESI) 在我们的 IAB 任职，其中包括来自 UCR 的基础研究员 Jernej Murn 博士和医学博士 Ana Tergas CoHCCC 的临床试验家和拉丁裔研究员承诺，我们将与规划和合作伙伴共同努力。 评估核心 (PEC) 并作为 U54 的监督机构，IAB 将每年与 U54 领导人会面两次 - 或者如果需要更频繁 - 为我们的 U54 提供战略方向、政策制定和评估 PEC、IAB 和 EAB 将对完整项目和试点项目进行年度审查。 核心。CAB 将评估项目和核心——特别是我们的社区外展核心并评估我们的项目和核心。 EAB、IAB 和 CAB 将与 U54 项目联合会面。 和核心领导者评估影响癌症健康差异和药物差异的总体进展和能力 开发和临床试验。