Career Enhancement Program

职业提升计划

• 批准号: 10708580
• 负责人: William E. Gillanders
• 金额: $ 17.97万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708580
• 关键词: Applications Grants; Award; Basic Science; Biometry; California; Cancer Biology; Cancer Etiology; Clinic; Clinical; Clinical Trials Design; Collaborations; Department chair; Development; Development Plans; Diagnosis; Disabled Persons; Discipline of obstetrics; Doctor of Philosophy; Early Diagnosis; Education; Educational Status; Ethics; Extramural Activities; Faculty; Feedback; Financial Support; Fostering; Funding; Gynecology; Image; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Medicine; Mentors; Minority; Nebraska; North Carolina; Outcome; Pancreas; Patient Care; Population Sciences; Prevention; Professional Competence; Research; Research Personnel; Research Support; System; Training; Translational Research; Universities; Washington; Woman; anticancer research; career; career development; improved; multidisciplinary; next generation; novel strategies; novel therapeutic intervention; pancreatic cancer patients; peer; programs; recruit; research and development; skills training; success; synergism; Applications Grants; Award; Basic Science; Biometry; California; Cancer Biology; Cancer Etiology; Clinic; Clinical; Clinical Trials Design; Collaborations; Department chair; Development; Development Plans; Diagnosis; Disabled Persons; Discipline of obstetrics; Doctor of Philosophy; Early Diagnosis; Education; Educational Status; Ethics; Extramural Activities; Faculty; Feedback; Financial Support; Fostering; Funding; Gynecology; Image; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Medicine; Mentors; Minority; Nebraska; North Carolina; Outcome; Pancreas; Patient Care; Population Sciences; Prevention; Professional Competence; Research; Research Personnel; Research Support; System; Training; Translational Research; Universities; Washington; Woman; anticancer research; career; career development; improved; multidisciplinary; next generation; novel strategies; novel therapeutic intervention; pancreatic cancer patients; peer; programs; recruit; research and development; skills training; success; synergism

PROJECT SUMMARY The SPORE in Pancreatic Cancer Career Enhancement Program (CEP) aims to recruit and support new independent investigators in translational pancreatic cancer research. Along with the Developmental Research Program (DRP), the CEP will provide financial support, didactic training, and mentored research opportunities to prepare investigators for independent careers in translational pancreatic cancer research. The CEP will extend current efforts to promote diversity in pancreatic cancer research through recruitment of women, minority, and disabled faculty. We propose the following specific aims: Specific Aim 1: Recruit and support new investigators in translational pancreatic cancer research. In addition to the NCI funds, a total of $323,000 in institutional support is committed in support of the CEP program. CEP awards will provide $75K per year for 2 years. Awardees will be junior faculty beginning their research careers or transitioning into translational pancreatic cancer research. Funded initiatives are expected to have a major translational component and focus on pancreatic cancer etiology, prevention, diagnosis, early detection, treatment, or population science. Specific Aim 2: Train and mentor junior faculty in translational pancreatic cancer research. All CEP awardees will be mentored by both a senior basic science and clinical mentor and will craft an individualized career development plan that includes didactic coursework, patient care, and career skills training. We will leverage institutional educational opportunities to include courses in clinical trial design, biostatistics, and ethics. The SPORE CEP Steering Committee will track and evaluate CEP awardees’ research and career development. Specific Aim 3: Foster inter-SPORE collaborations. An educational exchange with our peer Pancreatic or GI SPORE institutions (University of Nebraska, Mayo Clinic, John Hopkins, University of North Carolina, University of California System) allows CEP awardees to present their research, receive expert feedback, meet peer SPORE leadership, and develop collaborations. Content experts from peer SPORE institutions will perform critical reviews and provide formal feedback for CEP awardees’ extramural grant applications. Specific Aim 4: Promote participation of women, minority, and disabled investigators in pancreatic cancer research. Diversity Advisor Bettina Drake, PhD, MPH will guide recruitment, training, and retention of women, minority, and disabled investigators in pancreatic cancer research at all training levels. We have also added two diversity advisors to the Internal Advisory Board (IAB) to synergize the SPORE efforts with the WUSM wide initiative to hire and retain faculty of diverse backgrounds underrepresented in medicine. Relevance: These aims will support research the next generation of PDAC researchers and project to improve our understanding of pancreatic cancer biology and develop new therapeutic approaches

项目摘要 胰腺癌职业增强计划（CEP）的孢子旨在招募和支持新的 翻译胰腺癌研究的独立研究者。以及发展研究 计划（DRP），CEP将提供财务支持，教学培训，并指导研究机会 为翻译胰腺癌研究中的独立职业准备研究人员。 CEP将延伸 目前通过招募妇女，少数群体和 残疾教师。我们提出以下具体目标： 特定目的1：招募和支持翻译胰腺癌研究的新研究人员。在 除NCI基金外，共有323,000美元的机构支持以支持CEP计划。 CEP奖项将在2年内每年提供7.5万美元。获奖者将是初级教师开始研究 职业或过渡到转化胰腺癌研究。预计资助的倡议将有一个 主要的翻译成分和关注胰腺癌病因，预防，诊断，早期检测， 治疗或人口科学。 特定目标2：翻译胰腺癌研究中的火车和精神少年教师。所有CEP 获奖者将通过高级基础科学和临床精神来介绍，并将制作个性化的 职业发展计划，包括教学课程，患者护理和职业技能培训。我们将 利用机构教育的机会，包括临床试验设计，生物统计学和道德的课程。 孢子CEP指导委员会将跟踪和评估CEP获奖者的研究和职业发展。 特定目标3：培养跨间的合作。与同行胰腺或GI的教育交流 孢子机构（内布拉斯加州大学，梅奥诊所，约翰·霍普金斯大学，北卡罗来纳大学，大学 加利福尼亚系统）允许CEP获奖者介绍他们的研究，收到专家反馈，与同伴见面 孢子领导并发展合作。同伴孢子机构的内容专家将执行 批判性审查并为CEP获奖者的壁外赠款申请提供正式反馈。 特定目的4：促进妇女，少数群体和残疾调查员的参与 癌症研究。多样性顾问贝蒂纳·德雷克（Bettina Drake）博士，MPH博士将指导招聘，培训和保留 在所有培训水平上，妇女，少数民族和残疾研究人员在胰腺癌研究中。我们也有 在内部顾问委员会（IAB）中增加了两名多样性顾问，以使孢子的工作与WUSM协同作用 广泛的倡议旨在聘用和保留潜水员的教职员工，这些倡议在医学领域的代表性不足。 相关性：这些目标将支持研究下一代PDAC研究人员，并将其项目改进 我们对胰腺癌生物学的理解并开发新的治疗方法