Communicore Animal Facility (CAF) Renovation Phase III Part II

Communicore 动物设施 (CAF) 改造第三期第二部分

• 批准号: 7248297
• 负责人: AUGUST H BATTLES
• 金额: $ 70万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7248297
• 关键词: Accreditation; Address; Air Conditioning; Animal Housing; Animal Welfare; Animals; Area; Biohazardous Substance; Biomedical Research; Book Chapters; Commit; Communities; Complex; Consult; Consultations; Decontamination; Development; Doctor of Veterinary Medicine; Ensure; Environment; Environmental Health; Environmental air flow; Facility Designs; Florida; Funding; Health Sciences; Heating; Hydrogen Peroxide; International; Laboratories; Laboratory Animals; Laboratory Research; Methods; Monitor; Operative Surgical Procedures; Phase; Plants; Preparation; Process; Quality of Care; Quarantine; Research; Rodent Diseases; Route; Safety; Science; Services; Staging; Sterility; Sterilization for infection control; Surface; System; United States National Institutes of Health; Universities; Workplace; animal care; animal facility; animal resource; authority; base; building design; design; digital; experience; facility renovation; foot; improved; pressure; programs; vapor

DESCRIPTION (provided by applicant): In 2001 The University of Florida initiated a 10 year plan to improve, enlarge and centralize its animal resource program to provide the best possible environment for scientific inquiry, quality care to laboratory animals, and a safe work environment while ensuring conformity with the Animal Welfare Act and the Guide. This proposal describes a three-phase plan to modernize the largest existing animal facility, the Communicore Animal Facility (CAF), and further centralize the animal resource program. Phase I replaced the worn out (>30yr old) heating, ventilation, and air conditioning (HVAC) supply units of CAF but could not address the distribution and control deficiencies of the system. Phase II is in the planning stage and will construct a 62,000 gross square feet (gsf) addition to CAF as part of a 172,000 gsf Biomedical Sciences Building immediately adjacent to CAF. Phase III has three parts based on the aea served by the existing HVAC system. Phase III will replace the remainder of the worn out HVAC and reconfigure CAF. Planning for Part I which will enlarge and modernize the CAF ABSL3 suite is underway. Part 3 will renovate the east half of CAF and will be done last. This proposal is Part 2 of Phase III and will replace the portion of the worn out HVAC system that serves about 22,750 gsf of the CAF with a modern fully redundant HVAC system with digital controls and monitoring, utilizing self regulating pressure independent valves. In addition, the central surgery will be reconfigured to provide a restricted area with a prep room and surgery dedicated for animals with biohazards. The quarantine area will be reconfigured to provide an exit for potentially infectious caging and materials and their efficient decontamination. Additionally, the route of sterile caging into the ABSL3 from the new CAF Annex cage wash will be shortened by providing a new entrance and method for sterilizing incoming caging and material in an efficient manner. All large animal rooms, surgical suites, animal prep rooms and the quarantine and ABSL3 entrances will be constructed to utilize vapor phase hydrogen peroxide sterilization. Electrical service in animal rooms and the surgical suite will be upgraded. We propose partial funding of this project with the University providing $5.12 for each $1.00 requested from NIH.

描述（由申请人提供）： 2001年，佛罗里达大学制定了一项为期10年的计划，以改善，扩大和集中其动物资源计划，为科学询问，对实验动物的优质护理以及安全的工作环境提供最佳的环境，同时确保符合《动物福利法》和《指南》。该提案描述了一个三相计划，以现代化最大的现有动物设施，沟通动物设施（CAF），并进一步集中了动物资源计划。第一阶段取代了CAF的磨损（> 30岁）的加热，通风和空调（HVAC）供应单位，但无法解决系统的分布和控制不足。第二阶段处于计划阶段，将在CAF中建造62,000平方英尺（GSF），这是与CAF紧邻的172,000 GSF生物医学科学建筑的一部分。第三阶段根据现有HVAC系统提供的AEA分为三个部分。第三阶段将取代损坏的HVAC和重新配置CAF的其余部分。计划将扩大和现代化CAF ABSL3套件的计划正在进行中。第3部分将翻新CAF的东半部，最后完成。 该提案是第三阶段的第2部分，将用现代完全冗余的HVAC系统使用数字控制和监控，以使用自我调节的无独立压力阀，以使用现代完全冗余的HVAC系统为CAF提供约22,750 GSF。此外，将重新配置中央手术，为有限制区域提供专门针对具有生物危害动物的动物的准备室和手术。隔离区域将被重新配置，以提供潜在的感染性笼子和材料及其有效净化的出口。此外，通过提供新的入口和方法，以有效的方式为新的入口和方法提供新的入口和方法，从新的CAF附件清洗中将无菌笼式笼子进入ABSL3的途径将缩短。将建造所有大型动物室，外科套房，动物预备室以及隔离区和ABSL3入口，以利用蒸汽相过氧化氢灭菌。动物室和外科套件中的电气服务将升级。我们建议对该项目进行部分资金，而大学为NIH要求的每$ 1.00提供5.12美元。