Cell & Tissue Imaging and Data Science Core

细胞

• 批准号: 10714515
• 负责人: Sarah F Hamm-Alvarez
• 金额: $ 19.92万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10714515
• 关键词: Algorithmic Software; Artificial Intelligence; Biological; Center Core Grants; Confocal Microscopy; Consultations; Coupled; Data; Data Science Core; Development; Electron Microscopy; Equipment; Evaluation; Experimental Designs; Goals; Histology; Image; Image Analysis; Individual; Machine Learning; Methodology; Microscopic; Microscopy; Productivity; Research; Research Personnel; Research Project Grants; Resources; Services; Specimen; Technical Expertise; Techniques; Technology; Tissue imaging; Tissues; Vision research; advanced analytics; analytical tool; artificial intelligence algorithm; cell preparation; cellular imaging; cost; imaging modality; imaging science; imaging system; implementation tool; innovation; investigator training; light microscopy; live cell imaging; operation; tissue preparation; vision science

PROJECT SUMMARY: CELL & TISSUE IMAGING AND DATA SCIENCE CORE The Cell & Tissue Imaging and Data Science Core will enhance the activities and accomplishments of ongoing research projects by providing histology services, access to a range of advanced imaging equipment, and technical expertise for image analysis and implementation of artificial intelligence (AI) approaches. It will provide essential resources for microscopic evaluation of ocular tissues and extraction of biological data from images, thereby increasing the innovative capabilities of participating investigators for conducting productive vision research. The Core will provide equipment and technical expertise for performing histology, light/confocal and electron microscopy, live cell imaging, image analysis, and development/application of AI algorithms. The specific aims are to provide resources for: 1) performing histology of ocular tissue specimens; 2) enabling investigators to evaluate ocular tissues with the use of sophisticated light/confocal and electron microscopy and emerging imaging modalities; 3) training investigators and their research staff on the utility and operation of imaging equipment; 4) consultations on cell and tissue preparation and imaging for experimental design and appropriateness of techniques; 5) providing expertise and technical support for image analysis and development of AI methodologies.

项目摘要：细胞和组织成像和数据科学核心 细胞和组织成像和数据科学核心将增强正在进行的活动和成就 通过提供组织学服务，访问一系列高级成像设备的研究项目以及 图像分析和人工智能方法（AI）方法的技术专长。会 为眼组织评估和从中提取生物数据的基本资源 图像，从而增加参与研究人员进行生产的创新能力 视力研究。核心将为执行组织学提供设备和技术专长， 光/共聚焦和电子显微镜，活细胞成像，图像分析以及AI的开发/应用 算法。具体目的是提供：1）进行眼组织标本的组织学； 2）使研究人员能够使用复杂的光/共聚焦和电子评估眼组织 显微镜和新兴成像方式； 3）培训调查人员及其研究人员有关公用事业和 成像设备的操作； 4）就实验的细胞和组织制备和成像进行咨询 技术的设计和适当性； 5）为图像分析提供专业知识和技术支持和技术支持 AI方法的开发。