Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

提高女性高血压患者的意识：ROAR（农村、肥胖、危险）

• 批准号: 10714530
• 负责人: Jennifer C Sullivan
• 金额: $ 150.59万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10714530
• 关键词: Academy; Address; Adult; Age; American Heart Association; Awareness; Biological; Black Populations; Blood Pressure Monitors; Cardiovascular Diseases; Cause of Death; Cessation of life; Clinical; Communities; Community Outreach; Development; Disease; Education; Educational Curriculum; Educational Materials; Educational workshop; Ensure; Equipment; Experimental Designs; Faculty; Female; Funding; Goals; Guidelines; Healthcare; Healthcare Systems; Heart Diseases; Historically Black Colleges and Universities; Hypertension; Improve Access; Learning; Location; Medical; Medical Students; Mentors; Monitor; Obesity; Outcome; Patients; Pharmaceutical Preparations; Physicians; Pilot Projects; Population; Populations at Risk; Postdoctoral Fellow; Prevalence; Recommendation; Relative Risks; Research; Research Personnel; Research Support; Research Training; Risk; Rural; Schools; Science; Scientist; Sex Differences; Southeastern United States; Students; Techniques; Training; Trust; Universities; Woman; Work; biological sex; biomedical scientist; black women; blood pressure control; blood pressure elevation; burden of illness; cardiovascular disorder education; cardiovascular disorder risk; cardiovascular health; cardiovascular risk factor; career; college; community engagement; design; doctoral student; elementary school; empowerment; experimental study; health care availability; healthspan; high risk; improved; innovation; insight; interest; male; medical schools; member; men; modifiable risk; mortality; mortality risk; next generation; novel; pre-clinical; pre-doctoral; premature; sabbatical; sex; teacher; undergraduate student; young woman

More than 1 in 3 women are living with heart disease and many are unaware of the risks. Hypertension is a major modifiable risk factor for cardiovascular disease (CVD), and ~47% of adults in the US have hypertension. In ~85% of cases, the cause of hypertension is unknown and only ~50% of patients taking medication achieve blood pressure (BP) control to recommended levels. A critical barrier to limiting premature death from CVD is lack of awareness surrounding the risks of CVD. Our location in the Southeast of the US will contribute to our impact. The prevalence of hypertension and obesity are high in GA, MS, and SC. The prevalence of hypertension and associated risk is not equal among all populations. Indeed, the prevalence of hypertension in Black people in the US is among the highest in the world. Our overall goal is to transform academic and community understanding of sex as a biological variable (SABV) in the consideration of hypertension. We will accomplish this through the creation and dissemination of innovative educational content, the development of strategic partnerships, and enhanced community engagement in the Southeast of the US. This SCORE is designed to provide novel insight into the mechanisms controlling BP in females vs. males, develop a comprehensive educational platform on SABV in CVD extending from grade school to medical school, and increase awareness and education of CVD and the risks of uncontrolled hypertension in women across the health span through community outreach. This SCORE has 4 objectives. Objective 1 is to conduct cutting edge research to advance our understanding of sex-specific mechanisms that control BP to limit cardiovascular risk. Objective 2 is to develop a culturally diverse research pipeline of biomedical scientists trained in the field of SABV in CVD. Objective 3 is to establish a community outreach pipeline of trained scientists to increase awareness of SABV and promote optimal cardiovascular healthcare for men and women. Objective 4 is to empower the community to self-monitor and work to identify barriers to improving access to healthcare. The outcomes of our proposed SCORE include not only advances in science and training of the next generation of leaders in the study of the impact of biological sex on the development and progression of CVD, but also the development of a range of educational content that will be fully available to the Consortium. This will include 1) the development educational materials by medical illustrators for students/trainees at all stages, the community, and physicians, 2) establishing a SABV Mentoring Academy, 3) creating a SABV curriculum and workshop for students, fellows, and junior investigators. The impact of our work will be to increase recognition and awareness of the risks of CVD and hypertension to women across their health span and best practices for SAVB experimental design. Our comprehensive community outreach plan will also be critical to reach a highly at-risk population in the Southeast of the US to increase routine cardiovascular health monitoring and decrease the overall CVD burden on both the population and the healthcare system.

超过三分之一的女性患有心脏病，许多人并没有意识到其中的风险。高血压是一大 心血管疾病 (CVD) 的可改变危险因素，约 47% 的美国成年人患有高血压。在 约 85% 的病例高血压病因不明，仅约 50% 服用药物的患者达到高血压的效果 血压 (BP) 控制在推荐水平。限制 CVD 过早死亡的一个关键障碍是 对CVD风险缺乏认识。我们位于美国东南部的位置将有助于我们 影响。 GA、MS 和 SC 中高血压和肥胖的患病率较高。高血压患病率 所有人群的相关风险并不相同。事实上，黑人高血压患病率 美国是世界上最高的。我们的总体目标是改变学术和社区 在考虑高血压时将性别理解为生物变量（SABV）。我们将完成 通过创建和传播创新教育内容、制定战略 伙伴关系，并加强美国东南部的社区参与。此 SCORE 旨在 为控制女性与男性血压的机制提供新的见解，开发全面的 CVD中SABV教育平台从小学到医学院延伸，提高认识 心血管疾病教育以及女性在整个健康范围内不受控制的高血压风险 社区外展。该 SCORE 有 4 个目标。目标 1 是进行前沿研究以推进 我们对控制血压以限制心血管风险的性别特异性机制的理解。目标 2 是 开发一个由受过 CVD SABV 领域培训的生物医学科学家组成的文化多元化的研究渠道。 目标 3 是建立一个由受过培训的科学家组成的社区外展渠道，以提高对 SABV 的认识 促进男性和女性的最佳心血管保健。目标 4 是赋予社区权力 自我监控并努力找出改善医疗保健可及性的障碍。我们提议的结果 SCORE 不仅包括科学进步以及对下一代领导者的培训 生物性别对 CVD 的发生和进展的影响，而且还影响一系列疾病的发展 联盟将完全可以获得教育内容。这将包括 1) 发展教育 医学插画家为各个阶段的学生/学员、社区和医生提供的材料，2) 建立 SABV 指导学院，3) 为学生、研究员创建 SABV 课程和研讨会， 和初级调查员。我们工作的影响将是提高人们对风险的认识和认识 女性整个健康范围内的 CVD 和高血压以及 SAVB 实验设计的最佳实践。 我们全面的社区外展计划对于接触该地区的高危人群也至关重要 美国东南部地区将加强常规心血管健康监测并减轻总体心血管疾病负担 对人口和医疗保健系统都有影响。