Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

提高女性高血压患者的意识：ROAR（农村、肥胖、危险）

• 批准号: 10714530
• 负责人: Jennifer C Sullivan
• 金额: $ 150.59万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10714530
• 关键词: Academy; Address; Adult; Age; American Heart Association; Awareness; Biological; Black Populations; Blood Pressure Monitors; Cardiovascular Diseases; Cause of Death; Cessation of life; Clinical; Communities; Community Outreach; Development; Disease; Education; Educational Curriculum; Educational Materials; Educational workshop; Ensure; Equipment; Experimental Designs; Faculty; Female; Funding; Goals; Guidelines; Healthcare; Healthcare Systems; Heart Diseases; Historically Black Colleges and Universities; Hypertension; Improve Access; Learning; Location; Medical; Medical Students; Mentors; Monitor; Obesity; Outcome; Patients; Pharmaceutical Preparations; Physicians; Pilot Projects; Population; Populations at Risk; Postdoctoral Fellow; Prevalence; Recommendation; Relative Risks; Research; Research Personnel; Research Support; Research Training; Risk; Rural; Schools; Science; Scientist; Sex Differences; Southeastern United States; Students; Techniques; Training; Trust; Universities; Woman; Work; biological sex; biomedical scientist; black women; blood pressure control; blood pressure elevation; burden of illness; cardiovascular disorder education; cardiovascular disorder risk; cardiovascular health; cardiovascular risk factor; career; college; community engagement; design; doctoral student; elementary school; empowerment; experimental study; health care availability; healthspan; high risk; improved; innovation; insight; interest; male; medical schools; member; men; modifiable risk; mortality; mortality risk; next generation; novel; pre-clinical; pre-doctoral; premature; sabbatical; sex; teacher; undergraduate student; young woman

More than 1 in 3 women are living with heart disease and many are unaware of the risks. Hypertension is a major modifiable risk factor for cardiovascular disease (CVD), and ~47% of adults in the US have hypertension. In ~85% of cases, the cause of hypertension is unknown and only ~50% of patients taking medication achieve blood pressure (BP) control to recommended levels. A critical barrier to limiting premature death from CVD is lack of awareness surrounding the risks of CVD. Our location in the Southeast of the US will contribute to our impact. The prevalence of hypertension and obesity are high in GA, MS, and SC. The prevalence of hypertension and associated risk is not equal among all populations. Indeed, the prevalence of hypertension in Black people in the US is among the highest in the world. Our overall goal is to transform academic and community understanding of sex as a biological variable (SABV) in the consideration of hypertension. We will accomplish this through the creation and dissemination of innovative educational content, the development of strategic partnerships, and enhanced community engagement in the Southeast of the US. This SCORE is designed to provide novel insight into the mechanisms controlling BP in females vs. males, develop a comprehensive educational platform on SABV in CVD extending from grade school to medical school, and increase awareness and education of CVD and the risks of uncontrolled hypertension in women across the health span through community outreach. This SCORE has 4 objectives. Objective 1 is to conduct cutting edge research to advance our understanding of sex-specific mechanisms that control BP to limit cardiovascular risk. Objective 2 is to develop a culturally diverse research pipeline of biomedical scientists trained in the field of SABV in CVD. Objective 3 is to establish a community outreach pipeline of trained scientists to increase awareness of SABV and promote optimal cardiovascular healthcare for men and women. Objective 4 is to empower the community to self-monitor and work to identify barriers to improving access to healthcare. The outcomes of our proposed SCORE include not only advances in science and training of the next generation of leaders in the study of the impact of biological sex on the development and progression of CVD, but also the development of a range of educational content that will be fully available to the Consortium. This will include 1) the development educational materials by medical illustrators for students/trainees at all stages, the community, and physicians, 2) establishing a SABV Mentoring Academy, 3) creating a SABV curriculum and workshop for students, fellows, and junior investigators. The impact of our work will be to increase recognition and awareness of the risks of CVD and hypertension to women across their health span and best practices for SAVB experimental design. Our comprehensive community outreach plan will also be critical to reach a highly at-risk population in the Southeast of the US to increase routine cardiovascular health monitoring and decrease the overall CVD burden on both the population and the healthcare system.

超过三分之一的妇女患有心脏病，许多妇女没有意识到风险。高血压是主要的 心血管疾病（CVD）的可修改风险因素，在美国，约有47％的成年人患有高血压。在 〜85％的病例，高血压的原因尚不清楚，服用药物的患者中只有约50％ 血压（BP）控制到建议水平。限制CVD过早死亡的关键障碍是 CVD的风险缺乏意识。我们在美国东南部的位置将有助于我们 影响。高血压和肥胖症的患病率在GA，MS和SC中很高。高血压的患病率 在所有人群中，相关风险并不相等。确实，黑人高血压的患病率 在美国是世界上最高的。我们的总体目标是改变学术和社区 在考虑高血压时，将性作为生物变量（SABV）的理解。我们将完成 通过创建和传播创新的教育内容，战略的发展 合作伙伴关系，并增强了美国东南部的社区参与。该分数被设计为 提供有关控制女性与男性BP的机制的新颖洞察力，发展全面 CVD中SABV的教育平台从小学到医学院延伸，并提高意识 以及对CVD的教育以及整个健康范围内女性不受控制的高血压风险 社区宣传。该分数有4个目标。目标1是进行尖端研究以进步 我们对控制BP的性别特定机制的理解以限制心血管风险。目标2是 开发了在CVD中SABV领域培训的生物医学科学家的文化多样性研究管道。 目标3是建立训练有素的科学家的社区外展管道，以提高对SABV的认识 并促进男女最佳心血管医疗保健。目标4是赋予社区权力 自我监测并努力确定改善获得医疗保健的障碍。我们提议的结果 得分不仅包括科学进步和下一代领导者的培训 生物性别对CVD的发展和发展的影响，但也是一系列的发展 财团将充分使用的教育内容。这将包括1）发展教育 医疗插图画家的材料在各个阶段，社区和医生的材料，2） 建立SABV指导学院，3）为学生，研究员， 和初级调查人员。我们工作的影响将是提高认识和认识 CVD和女性在其健康范围内对女性的高血压，以及SAVB实验设计的最佳实践。 我们全面的社区外展计划也至关重要 美国东南部增加常规心血管健康监测并减轻总体CVD负担 在人口和医疗保健系统上。