The Association Between Diet and Bowel Preparation

饮食与肠道准备之间的关系

• 批准号: 9116186
• 负责人: BRIAN C JACOBSON
• 金额: $ 17.58万
• 依托单位: BOSTON MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-29 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9116186
• 关键词: Address; Adherence; Age; Agreement; Applications Grants; Aspirate substance; Boston; Cathartics; Classification; Client satisfaction; Colon; Colonoscopy; Consumption; Dairy Products; Data; Detection; Development; Diet; Dietary Component; Dietary Intervention; Dietary intake; Education; Effectiveness; Endoscopy; Ensure; Feasibility Studies; Fiber; Flushing; Food; Future; Gelatin; Gender; Health; Instruction; Intestines; Lesion; Liquid substance; Malignant - descriptor; Measures; Meat; Nutritional; Nutritional Study; Nuts; Patients; Pilot Projects; Polyps; Premalignant; Preparation; Procedures; Process; Public Health; Race; Research; Rice; Sampling; Screening procedure; Seeds; Testing; Time; United States; Validation; Vegetables; Water; base; design; dietary restriction; drinking; evidence base; food quality; laxative; novel; nutrition; prospective test; satisfaction; tool

 DESCRIPTION (provided by applicant): An estimated 11 to 14 million colonoscopies are performed annually in the United States, yet very limited information exists describing the impact of specific foods consumed on the days prior to the pre-colonoscopy bowel preparation. Consequently, any recommended dietary restrictions that accompany bowel purgatives are based on limited scientific evidence and vary across endoscopy units. These non-standardized dietary restrictions place constraints on people preparing for a colonoscopy and may result in decreased patient satisfaction with the procedure and perhaps decreased compliance with the preparation. If specific dietary restrictions are indeed necessary to ensure maximizing the endoscopist's ability to detect malignant or pre- malignant lesions, then identification of optimal instructions becomes an important public health endeavor. The proposed nutritional study will begin to examine, in a novel and rigorous manner, the effect of diet on adequacy of bowel preparation for colonoscopy. This study will address observed national variability in pre- colonoscopy dietary instructions and permit, for the first time, the development of evidence-based, culturally- sensitive dietary options for patients preparing for colonoscopy. A secondary aim is the validation of a novel, bowel preparation classification scale that describes colonic contents during colonoscopy. This proposed new scale was designed specifically to measure the impact of dietary interventions in the days preceding colonoscopy for nutritional research.

 描述（由申请人提供）：据估计，美国每年进行 11 至 1400 万例结肠镜检查，但描述结肠镜检查前肠道准备检查前几天食用的特定食物（任何推荐的食物）的影响的信息非常有限。伴随肠道泻药的饮食限制基于有限的科学证据，并且因内窥镜检查单位而异。这些非标准化的饮食限制对准备结肠镜检查的人造成了限制，可能导致患者对手术的满意度下降，并可能降低患者的依从性。如果确实需要特定的饮食限制以确保最大限度地提高内窥镜医师检测恶性或癌前病变的能力，则确定最佳的方法。 拟议的营养研究将以一种新颖而严格的方式开始研究饮食对结肠镜检查肠道准备充分性的影响。首次允许为准备结肠镜检查的患者制定基于证据的、文化敏感的饮食选择，第二个目的是验证一种描述结肠镜检查期间结肠内容物的新型肠道准备分类量表。专门设计用于测量饮食的影响在结肠镜检查前几天进行干预以进行营养研究。

项目成果

The association among diet, dietary fiber, and bowel preparation at colonoscopy.

饮食、膳食纤维和结肠镜检查时肠道准备之间的关联。

• 发表时间: 2018
• 影响因子: 7.7
• 作者: Leszczynski, Anna M;MacArthur, Kristin L;Nelson, Kerrie P;Schueler, Samuel A;Quatromoni, Paula A;Jacobson, Brian C
• 通讯作者: Jacobson, Brian C