Pediatric Heart network DCC

儿科心脏网络 DCC

基本信息

批准号：
8862520
负责人：
Julie Elaine Miller
金额：
$ 905.41万
依托单位：
NEW ENGLAND RESEARCH INSTITUTES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
起止时间：
2001-09-06 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8862520
关键词：
Adolescent and Young Adult Arrhythmia Bioinformatics Books Budgets Cardiology Cardiovascular system Case Report Form Certification Child Childhood Clinical Clinical Research Clinical Trials Code Collaborations Communication Congenital Heart Defects Contracts Core Facility Data Data Coordinating Center Data Quality Data Set Databases Development Diagnostic Electronics Event Funding Health Heart Heart Abnormalities Heart Diseases Image Inflammatory Information Systems Journals Laboratories Leadership Maintenance Manuals Manuscripts Measurement Medical Medical center Mission Monitor Myocardium Myopathy National Heart, Lung, and Blood Institute New England Occupational activity of managing finances Online Systems Operative Surgical Procedures Pediatric cardiology Performance Persons Pharmaceutical Preparations Policies Positioning Attribute Preparation Principal Investigator Procedures Process Program Development Publications Quality Control Quality of life Reading Reporting Research Research Design Research Infrastructure Research Institute Research Personnel Research Support Resources Role Safety Sample Size Schedule Science Scientist Services Site System Teleconferences Testing Training Translational Research Writing biobank clinical research site data acquisition design distributed data improved meetings operation payment programs protocol development statistics symposium tool web site

项目摘要

DESCRIPTION (provided by applicant): New England Research Institutes, Inc. (NERI) is applying to continue its 10-year role as the Data Coordinating Center (DCC) for the Pediatric Heart Network (PHN). The PHN will continue as a cooperative network of up to 8 Clinical Centers, 15 auxiliary sites, a DCC, a Network Chair, and NHLBI Project Scientists. The objectives of the PHN are to 1) provide an infrastructure for multi-center collaborative clinical research, and 2) to evaluate diagnostic, medical, interventional, and surgical therapies for congenital heart defects, inflammatory heart disease, heart muscle disease, and arrhythmias. As the DCC, NERI will continue to provide scientific and logistical support for the next cycle of the Network, with key responsibilities and functions for leadership in study design and statistics, overall study coordination and management of data acquisition; leadership in development activities for bioinformatics infrastructure and tools; electronic information and data systems; logistical and support services; and management and distribution of Network funds. A multiple PI leadership plan is proposed to continue the leadership roles shared by Dr. Sleeper (Clinical and Statistical Science) and Dr. Tennstedt (Network Operations), with clearly delineated roles and responsibilities for leading and directing the DCC, intellectually and operationally. Importantly, the DCC staff will be organized to include a Network Manager who is also the Manager for the NHLBI Bench to Bassinet Program. This will position the DCC to facilitate integration of the PHN as the clinical trials component of the B2B Program.

描述（由申请人提供）：新英格兰研究机构 (NERI) 正在申请继续担任儿科心脏网络 (PHN) 数据协调中心 (DCC) 的 10 年职责。 PHN 将继续作为一个由多达 8 个临床中心、15 个辅助中心、一个 DCC、一名网络主席和 NHLBI 项目科学家组成的合作网络。 PHN 的目标是 1) 为多中心协作临床研究提供基础设施，2) 评估先天性心脏病、炎症性心脏病、心肌疾病和心律失常的诊断、医疗、介入和手术治疗。作为DCC，NERI将继续为网络的下一个周期提供科学和后勤支持，其主要职责和职能是领导研究设计和统计、整体研究协调和数据采集管理；领导生物信息学基础设施和工具的开发活动；电子信息和数据系统；后勤和支持服务；网络资金的管理和分配。提出了一项多重 PI 领导计划，以继续由 Sleeper 博士（临床和统计科学）和 Tennstedt 博士（网络运营）共同承担领导角色，并明确界定在智力和运营方面领导和指导 DCC 的角色和责任。重要的是，DCC 工作人员中将包括一名网络经理，他也是 NHLBI 长凳到摇篮计划的经理。这将使 DCC 能够促进 PHN 整合为 B2B 计划的临床试验组成部分。