Core Grant for Vision Research-Animal Module Core

视觉研究核心资助-动物模块核心

• 批准号: 10705716
• 负责人: Patricia Ann D'Amore
• 金额: $ 28.72万
• 依托单位: SCHEPENS EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10705716
• 关键词: Anesthesia procedures; Animal Experimentation; Animal Experiments; Animal Model; Animals; Blindness; Breeding; Consult; Core Grant; Development; Equipment; Eye diseases; Fundus photography; Genotype; Goals; Image; Laboratory Animal Models; Maintenance; Microscope; Mission; Operative Surgical Procedures; Pathogenesis; Pharmaceutical Preparations; Phenotype; Postoperative Care; Protocols documentation; Research; Resource Sharing; Rodent; Services; System; Techniques; Testing; Training; Transgenic Organisms; Vision research; Visual; animal imaging; animal resource; disorder prevention; mouse model; mutant mouse model; novel; programs; research faculty; research study; visual dysfunction

Animal Resource Project Summary/Abstract Our institute’s mission is to conduct research that will lead to a better understanding, treatment and prevention of diseases that cause visual dysfunction and blindness. To achieve these goals, the research faculty uses a variety of laboratory animal models that are essential for elucidating the pathogenesis of a diverse group of ocular diseases. The primary purpose of the Animal Resource Module is to provide expertise and assistance in animal imaging and visual assessment, devise surgical plans for novel animal models, consolidate rodent colonies as shared resources, and to provide extensive veterinary support along with pre-, intra-, and post- operative care. The animal resource module staff trains and provides support on the use of the ERG, HRT, OCT, slit lamp microscopes, and fundus photography systems, and maintain and upkeep imaging spaces and equipment. They also troubleshoot the breeding of difficult transgenic lines, conduct the genotyping and phenotyping of mouse models that are central to many of our research studies.

动物资源项目摘要/摘要 我们的研究所的使命是进行研究，以提高更好的理解，治疗 并预防引起视觉功能障碍和失明的疾病。实现这些 目标，研究教师使用的各种实验室动物模型对于 阐明各种眼部疾病的发病机理。主要目的 动物资源模块是在动物成像和视觉上提供专业知识和帮助 评估，制定新型动物模型外科手术计划，将啮齿动物菌落巩固为 共享资源，并提供广泛的兽医支持以及前，内部和后 手术护理。动物资源模块员工训练并为使用 ERG，HRT，OCT，SLIT灯显微镜和眼底摄影系统，并维护和维护和 维护成像空间和设备。他们还解决了困难的繁殖 转基因线，进行基因分型和表型，对小鼠模型的核心 我们的许多研究。