2023 Barrier Function of Mammalian Skin Gordon Research Conferences and Gordon Research Seminar

2023年哺乳动物皮肤屏障功能戈登研究会议及戈登研究研讨会

• 批准号: 10683587
• 负责人: Marjana Tomic-Canic
• 金额: $ 2.4万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683587
• 关键词: Aging; Atmosphere; Basic Science; Big Data; Biochemical; Biological Process; Biology; Biomedical Engineering; Biophysics; COVID-19 pandemic; Cells; Cellular biology; Characteristics; Chemical Exposure; Chemicals; Clinical; Clinical Research; Collaborations; Communities; Cosmetics; Coupled; Dedications; Dehydration; Dermatologic; Dermatology; Desiccation; Development; Diagnostic; Discipline; Discrimination; Disease; Drug Delivery Systems; Environment; Environmental Science; Ethnic Origin; Exposure to; Feedback; Functional disorder; Funding; Future; Gender; Genomics; Goals; Health; Health protection; Homeostasis; Hour; Human; Image; Immune response; Industry; Intelligence; Interdisciplinary Study; International; Knowledge; Learning; Lesbian Gay Bisexual Transgender; Life; Maintenance; Mentors; Microbiology; Modeling; Molecular; Oral; Participant; Pathology; Pathway interactions; Pharmacy (field); Physical Chemistry; Play; Postdoctoral Fellow; Privatization; Race; Research; Research Personnel; Risk; Role; Scholarship; Science; Scientist; Secure; Skin; Systemic disease; Technology; Therapeutic; Time; Transdermal substance administration; Translational Research; Translations; Travel; Underrepresented Minority; United States National Institutes of Health; Water; Woman; Work; Xenobiotics; career; clinical care; clinical diagnostics; community involvement; cost; economic impact; ethnic diversity; ethnic minority; forging; frontier; graduate student; improved; innovation; meetings; microbiome; microbiota; multidisciplinary; novel; novel therapeutic intervention; peer; precision medicine; programs; skin barrier; success; symposium; targeted delivery; wound healing

PROJECT SUMMARY Established in 1989 The Gordon Research Conference on Barrier Function of Mammalian Skin, for over 30 years remains to be the premiere international scientific meeting that successfully incorporates multiple disciplines and topics focusing on understanding the mechanisms of mammalian skin barrier and its maintenance in health and disease. The success of the meeting (evidenced by diversity of topics and speakers, size of the applicant pool, extremely positive reviews) derives from variety in topics, gender/race/ethnicity inclusion and commitment to promote scientists in the early stage of their careers. The overarching theme of the 2023 conference is "Intelligent and personalized skin barrier: translation of cell and biology, bioengineering and physical chemistry” which will bring together a unique blend of young investigators and prominent leaders to present latest developments in cell biology, pathology, microbiology, environmental sciences, bioengineering, biophysics, physical chemistry, and drug delivery focusing on utilizing precision medicine approaches to personalize clinical care and minimize chemical exposure. The overarching objective and long-term goals of this conference is to present novel discoveries and discuss the latest developments in these different fields of expertise through both formal and informal discussions and to provide a platform for new collaborative opportunities of synergistic team approaches to facilitate future discoveries and novel therapeutic approaches that will advance this multi-disciplinary field. Moreover, the goal is also to stimulate discussions regarding new frontiers and future big questions and challenges as well as approaches to tackle them. To promote discussions and diversify of speakers and topics, all speakers will be newly invited (did not speak at the 2019 GRC) and 30% of the program will be dedicated to young investigators selected from submitted abstracts. We will hold a power hour to facilitate important discussions regarding various aspects of “discrimination in science” including promotion of racial/ethnic diversity by bringing together scientists from the diverse community of researchers working on the epidermal barrier. The major themes of the 2023 conference will include aging and environmental effects on barrier, cross talk of microbiota and host-response in homeostasis and disease, approaches to predict permeation and chemical risk exposure, optimization of drug delivery, big data and precision medicine (ranging from genomics, clinical diagnostics to imaging), and optimizing therapeutics. While these themes define the agenda, the program will incorporate short oral talks selected from the submitted abstracts. Each session will incorporate 1-2 such short talks, maximizing the opportunity to include latest research and provide a platform and visibility to young trainees. The new advances, knowledge sharing, and new multi-disciplinary collaborations forged at this conference, coupled with the interactions between attendees, will greatly advance the shared goal of understanding epidermal barrier function to improve health both locally, in the skin, and systemically.

项目摘要 成立于1989年的戈登哺乳动物皮肤屏障功能研究会议已有30多年了 仍然是首映的国际科学会议，成功纳入了多个学科和 主题着重于了解哺乳动物皮肤屏障的机制及其在健康方面的维护和 疾病。会议的成功（由主题和演讲者的多样性，适用的池的大小来证明， 非常积极的评论）源于主题，性别/种族/种族包容性的多样性和对 在职业生涯的早期促进科学家。 2023会议的总体主题是“智能 和个性化的皮肤障碍：细胞和生物学的翻译，生物工程和物理化学”将会 将年轻调查员和著名领导人组成的独特融合在一起，展示 细胞生物学，病理学，微生物学，环境科学，生物工程，生物物理学，物理化学， 和药物输送的重点是使用精确医学方法来个性化临床护理并最小化 化学暴露。这次会议的总体目标和长期目标是介绍小说 发现和讨论通过正式和 非正式讨论，并为协同团队方法的新协作机会提供一个平台 为了促进未来的发现和新颖的治疗方法，这些方法将推进这一多学科领域。 此外，目标还是刺激有关新边界和未来大问题的讨论， 挑战以及应对它们的方法。为了促进演讲者和主题的讨论和多元化， 所有演讲者都将受到新的邀请（在2019年GRC上没有发言），该计划的30％将致力于 年轻的调查人员从提交的摘要中选出。我们将持有一个动力时光，以促进重要 关于“科学歧视”的各个方面的讨论，包括促进种族/种族多样性 通过汇集来自研究表皮障碍的研究人员的科学家。这 2023年会议的主要主题将包括对障碍的衰老和环境影响，谈论 微生物群和宿主反应在体内稳态和疾病中，预测渗透和化学风险的方法 暴露，药物输送的优化，大数据和精确药物（从基因组学，临床范围 诊断成像），并优化治疗。这些主题定义了Agernda，但该程序将 合并从提交的摘要中选择的简短口头谈判。每个会话将使1-2次这样的简短 会谈，最大限度地有机会包括最新研究并为年轻学员提供平台和可见性。 在本次会议上，新的进步，知识共享和新的多学科合作忘记了 再加上与会者之间的互动，将大大促进理解的共同目标 表皮屏障功能可在本地，皮肤和系统上改善健康。