2023 Silk Proteins and the Transition to Biotechnologies Gordon Research Conference

2023 年丝蛋白和向生物技术的过渡戈登研究会议

• 批准号: 10681751
• 负责人: DAVID L. KAPLAN
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10681751
• 关键词: Academia; Acceleration; Address; Antibiotics; Area; Biocompatible Materials; Biological Models; Biology; Biomedical Engineering; Biotechnology; Bombyx; Chemistry; Collaborations; Development; Devices; Emerging Technologies; Engineering; Environment; Enzymes; Exhibits; Fostering; Foundations; Friends; Funding; Future; Goals; Growth Factor; Harvest; Hour; Implant; Industry; Inflammation; Inflammatory Response; Intervention; Mechanics; Medical; Medical Device; Medical Technology; Medicine; Modeling; Molecular Weight; National Institute of Biomedical Imaging and Bioengineering; Pharmaceutical Preparations; Polymers; Process; Property; Protein Family; Proteins; Regenerative Medicine; Research; Running; Schedule; Science; Silk; Spiders; Structure; Students; System; Technology; Textiles; Therapeutic; Translations; Underrepresented Populations; Variant; Virginia; Water; Woman; amphiphilicity; aqueous; biodegradable polymer; biomaterial compatibility; commercialization; copolymer; design; implanted sensor; in vivo; insight; knowledge base; materials science; meetings; multidisciplinary; novel; physical science; recruit; self assembly; symposium; tissue reconstruction; tissue regeneration; translational impact; translational potential; vaccine delivery; wearable sensor technology

Project Summary The goal of this project is to support a Gordon Research Conference on silk materials. The objective of the conference is to cover research and technologies that are emerging utilizing silk-based biomaterials and to catalyze further translational efforts in the field. The plan is to bring together experts in the field of silk science from academia and industry from around the world to focus on current advances in the understanding and utilization of this unique family of proteins from silkworms and spiders, from both fundamental and applied perspectives, and to foster collaborations with the aim to give everyone an equal platform to showcase their science and technologies. Silk Biomaterials and Engineering Platform - Developing further fundamental and translational insight into silk protein self-assembly, bioengineering, chemistry, processing and new materials engineering provides the foundation for a wide range of advances in the field of protein-based biomaterials. These insights also impact broader needs in biomaterials science and engineering, utilizing silk as a unique model polymer due to its block copolymer structure, high molecular weight amphiphilic features, and aqueous processability. These insights should inform new ideas in biomaterials science and engineering, new silk protein-based products for medical needs, and new trainees excited and informed to join the field. Medical Interventions - Impact in the field of implantable, biocompatible and fully degradable medical devices is anticipated from the discussions at the GRC. We anticipate that the information gained at the meeting should facilitate new medical impact, from vaccine delivery to tissue reconstruction and implantable and wearable sensors. The conference emphasizes diversity and women with strong representation, while providing support for inclusion of under-represented groups with funding support for attendance. We also have scheduled a GRC power hour afternoon session, which will be run by women in STEM. Broader Impact - The use of silk in medically relevant areas is timely related to the push towards sustainable technologies and green chemistry, as silk is generated in an eco-friendly manner and harvested in water for use in textiles today. The transition toward medical needs with this novel protein-based material, along with broader implications in new environmentally related applications, offers to propel new silk technologies forward; utilizing water, exploiting degradability, and meeting energy and related requirements.

项目摘要 该项目的目的是支持戈登丝绸材料研究会议。目的 会议旨在涵盖利用基于丝绸的生物材料的新兴研究和技术 催化该领域的进一步翻译工作。该计划是将丝绸科学领域的专家汇集在一起 来自世界各地的学术界和工业，重点关注当前的理解进步和 从基本和应用中利用蚕和蜘蛛的这种独特的蛋白质家族 观点，并促进合作，目的是为每个人提供平等的平台来展示他们的 科学和技术。丝绸生物材料和工程平台 - 开发进一步的基本和 对丝绸蛋白质组装，生物工程，化学，加工和新材料的转化洞察力 工程为基于蛋白质的生物材料领域的广泛进步奠定了基础。 这些见解还影响了生物材料科学和工程的更广泛需求，将丝绸作为独特 由于其块共聚物结构，高分子量两亲性特征和水性引起的模型聚合物 加工性。这些见解应为生物材料科学与工程学的新想法提供信息，新丝绸 基于蛋白质的医疗需求产品，新学员兴奋并得知加入该领域。医疗的 干预措施 - 在可植入，生物相容性和完全降解的医疗设备领域的影响是 从GRC的讨论中预期。我们预计会议上获得的信息应该 促进新的医疗影响，从疫苗输送到组织重建以及可植入和可穿戴的 传感器。会议强调多样性和具有强烈代表的女性，同时提供支持 为了包括代表性不足的团体，并为出勤提供资金支持。我们还安排了GRC Power Hour下午会议将由STEM的女性进行。 更广泛的影响 - 在医学相关领域中使用丝绸与朝着可持续发展的推动有关 技术和绿色化学，作为丝绸以环保的方式产生，并在水中收获 今天在纺织品中使用。这种新型基于蛋白质的材料以及 在新的环境相关应用程序中的更广泛含义，提出推动新丝绸技术的提议 向前;利用水，利用降解性并满足能量和相关要求。