The Case Medical Student Summer Research Program (MSSRP)

案例医学生暑期研究计划 (MSSRP)

• 批准号: 10701676
• 负责人: Fabio Cominelli
• 金额: $ 8.56万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-09 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10701676
• 关键词: Advisory Committees; Area; Basic Science; Clinic; Clinical Research; Collaborations; Cost Sharing; Development; Diabetes Mellitus; Digestive System Disorders; Direct Costs; Educational Curriculum; Environment; Evaluation; Funding; Goals; Group Meetings; Infection; Inflammation; Infrastructure; Institution; Investigation; Kidney Diseases; Liver diseases; Medical Education; Medical Students; Medical center; Mentors; Metabolic Diseases; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Physicians; Process; Productivity; Program Evaluation; Qualifying; Request for Applications; Research; Research Personnel; Research Project Grants; Resources; Scientist; Strategic Planning; Students; Training; Training Programs; United States National Institutes of Health; University Hospitals; Writing; career development; faculty mentor; innovation; interest; lectures; medical schools; programs; summer research; tumorigenesis

PROJECT SUMMARY This T35 competitive renewal application requests continued funding for the Case Medical Student Summer Research Program (MSSRP). The overall goal of the program is to promote career development for physician scientists who will choose biomedical investigation as an essential component of their long-term professional development, with particular focus on the mission areas of the NIDDK and NIDDK-related research. These include: 1) Digestive Diseases, 2) Liver Diseases, 3) Diabetes & Metabolic Diseases, 4) Kidney Diseases, 5) GI Tumorigenesis, and 6) Inflammation/Infection. The program educates medical students using a mentor- based research approach over an 8-week training period between their 1st and 2nd years of medical school. The T35 program is based on strategic planning, consolidated efforts, and close academic integration of the CWRU School of Medicine (SoM), University Hospitals (UH) Cleveland Medical Center, the Cleveland Clinic, MetroHealth, and the Louis Stokes VA Medical Center, which provides a superb programmatic infrastructure. The faculty mentors from these institutions sustain a reputation of excellence based on superior clinical and basic research, ample funding from the NIDDK and NIDDK-related institutes ($39.8M annual direct costs from NIH; $15.1M from NIDDK alone), and combined research space in excess of 100,000 ft2. The Case MSSRP has an established track-record of selecting highly-qualified medical students through a formal application and evaluation process that identifies a research project and mentor from investigators working in a research area related to the NIDDK mission. Program evaluation and student progress is overseen by the T35 Executive and Internal Advisory Committees. Students submit a written abstract and present their findings during the Lepow Medical Student Research Day held in September. A unique aspect of the program is the multiple PI/PD approach, which allows research to span departmental boundaries and enlist preceptors with a tradition of highly-productive collaboration and who have trained a large number of young investigators in an interdisciplinary manner. The 50 mentors from 19 departments, representing a wide range of research expertise, offer a multiplicity of research opportunities that are tailored to the scientific interest of each trainee. Our innovative curriculum includes weekly group meetings, didactic lectures, and a three-day hands-on course held at the start of the 8-week research period. To assess the long-term impact of the program, we collaborate with the Medical Education and Alumni Affairs offices to track medical students up to 20 years after graduation. Based on the high number of applicants during the previous funding period, we are requesting to expand NIDDK support by an additional 5 students per year (15 total NIDDK-supported trainees). We have strong institutional support, documented by provision of space and resources, cost-sharing, as well as support from the CTSC and NIDDK-funded Cleveland DDRCC. Therefore, the academic environment continues to be ideal to sustain the overall objectives of this NIDDK-focused T35 medical student short-term training program.

项目概要 此 T35 竞争性续签申请要求为凯斯医学生暑期项目继续提供资金 研究计划（MSSRP）。该计划的总体目标是促进医生的职业发展 选择生物医学研究作为其长期专业的重要组成部分的科学家 发展，特别关注 NIDDK 的任务领域和 NIDDK 相关研究。这些 包括：1) 消化系统疾病，2) 肝脏疾病，3) 糖尿病及代谢疾病，4) 肾脏疾病，5) 胃肠道肿瘤发生，以及 6) 炎症/感染。该计划使用导师来教育医学生—— 医学院第一年和第二年之间为期 8 周的培训期间基于研究方法。 T35项目基于战略规划、综合努力和学术紧密结合 CWRU 医学院 (SoM)、大学医院 (UH) 克利夫兰医学中心、克利夫兰诊所、 MetroHealth 和 Louis Stokes VA 医疗中心，提供一流的程序化基础设施。 来自这些机构的教师导师凭借卓越的临床和能力维持着卓越的声誉。 基础研究，来自 NIDDK 和 NIDDK 相关机构的充足资金（每年 3980 万美元的直接费用 NIH;仅 NIDDK 就提供了 1510 万美元），综合研究空间超过 100,000 平方英尺。案例 MSSRP 拥有通过正式申请选拔高素质医学生的良好记录，并且 评估过程，从研究领域工作的研究人员中确定研究项目和导师 与 NIDDK 使命相关。项目评估和学生进度由 T35 执行人员监督 内部咨询委员会。学生提交书面摘要并在 Lepow 期间展示他们的发现 九月举行医学生研究日。该计划的一个独特之处是多重 PI/PD 方法，它允许研究跨越部门界限并招募具有传统的导师 高效的合作，并在一个领域培训了大量年轻的研究人员 跨学科的方式。来自19个院系的50位导师，代表了广泛的研究领域 专业知识，提供根据每位学员的科学兴趣量身定制的多种研究机会。 我们的创新课程包括每周小组会议、教学讲座和为期三天的实践课程 在为期 8 周的研究期开始时举行。为了评估该计划的长期影响，我们合作 与医学教育和校友事务办公室合作，跟踪医学生长达 20 年后的情况。 鉴于上一资助期间申请人数量众多，我们请求扩大资助范围 NIDDK 每年额外支持 5 名学生（NIDDK 支持的培训生总数为 15 名）。我们有强大的 机构支持，记录为提供空间和资源、费用分摊以及来自 CTSC 和 NIDDK 资助的克利夫兰 DDRCC。因此，学术环境依然理想 维持以 NIDDK 为重点的 T35 医学生短期培训计划的总体目标。

项目成果

A survey of physician training and credentialing in endoscopic submucosal dissection in the United States.

• DOI: 10.1007/s00464-021-08565-0
• 发表时间: 2022-05
• 期刊: Surgical endoscopy
• 作者: Mistry S;Alaber O;Chandar AK;Perez LKM;Dumot J;Bhatt A;Chak A
• 通讯作者: Chak A

Digestive Manifestations in Patients Hospitalized With Coronavirus Disease 2019.

• DOI: 10.1016/j.cgh.2020.09.041
• 发表时间: 2021-07
• 期刊: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
• 作者: Elmunzer BJ;Spitzer RL;Foster LD;Merchant AA;Howard EF;Patel VA;West MK;Qayed E;Nustas R;Zakaria A;Piper MS;Taylor JR;Jaza L;Forbes N;Chau M;Lara LF;Papachristou GI;Volk ML;Hilson LG;Zhou S;Kushnir VM;Lenyo AM;McLeod CG;Amin S;Kuftinec GN;Yadav D;Fox C;Kolb JM;Pawa S;Pawa R;Canakis A;Huang C;Jamil LH;Aneese AM;Glamour BK;Smith ZL;Hanley KA;Wood J;Patel HK;Shah JN;Agarunov E;Sethi A;Fogel EL;McNulty G;Haseeb A;Trieu JA;Dixon RE;Yang JY;Mendelsohn RB;Calo D;Aroniadis OC;LaComb JF;Scheiman JM;Sauer BG;Dang DT;Piraka CR;Shah ED;Pohl H;Tierney WM;Mitchell S;Condon A;Lenhart A;Dua KS;Kanagala VS;Kamal A;Singh VK;Pinto-Sanchez MI;Hutchinson JM;Kwon RS;Korsnes SJ;Singh H;Solati Z;Willingham FF;Yachimski PS;Conwell DL;Mosier E;Azab M;Patel A;Buxbaum J;Wani S;Chak A;Hosmer AE;Keswani RN;DiMaio CJ;Bronze MS;Muthusamy R;Canto MI;Gjeorgjievski VM;Imam Z;Odish F;Edhi AI;Orosey M;Tiwari A;Patwardhan S;Brown NG;Patel AA;Ordiah CO;Sloan IP;Cruz L;Koza CL;Okafor U;Hollander T;Furey N;Reykhart O;Zbib NH;Damianos JA;Esteban J;Hajidiacos N;Saul M;Mays M;Anderson G;Wood K;Mathews L;Diakova G;Caisse M;Wakefield L;Nitchie H;Waljee AK;Tang W;Zhang Y;Zhu J;Deshpande AR;Rockey DC;Alford TB;Durkalski V;North American Alliance for the Study of Digestive Manifestations of COVID-19
• 通讯作者: North American Alliance for the Study of Digestive Manifestations of COVID-19

Age of diagnosis in familial Barrett's associated neoplasia.

• DOI: 10.1007/s10689-021-00239-z
• 发表时间: 2022-01
• 期刊: Familial cancer
• 影响因子: 2.2

UV-C tower for point-of-care decontamination of filtering facepiece respirators.

• DOI: 10.1016/j.ajic.2020.11.010
• 发表时间: 2021-04
• 期刊: American journal of infection control
• 影响因子: 4.9
• 作者: Kayani BJ;Weaver DT;Gopalakrishnan V;King ES;Dolson E;Krishnan N;Pelesko J;Scott MJ;Hitomi M;Cadnum JL;Li DF;Donskey CJ;Scott JG;Charnas I
• 通讯作者: Charnas I