Biostatistics and Data Management Core (BDM-Core)

生物统计和数据管理核心（BDM-Core）

• 批准号: 10701921
• 负责人: Salma Musaad
• 金额: $ 4.19万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-09 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10701921
• 关键词: Accelerometer; Area; Behavior; Biometry; Biostatistics Core; Child; Child Health; Child Nutrition; Clinical Research; Clinical Trials; Clinical Trials Data Monitoring Committees; Clinical Trials Design; Cognitive; Collaborations; Collection; Communication; Data; Data Analyses; Data Element; Data Set; Data Storage and Retrieval; Databases; Development; Doctor of Philosophy; Documentation; Education and Outreach; Electronics; Ensure; Epidemiology; Equation; Evaluation; Experimental Designs; Floor; Fostering; Gastroparesis; Genetic; Goals; Health; Health Sciences; Housing; Human Resources; Illinois; Individual; Information Dissemination; Intervention; Kidney Diseases; Knowledge; Lead; Longitudinal cohort study; Measures; Medicine; Meta-Analysis; Methodology; Methods; Mission; Modeling; Multi-Ethnic Study of Atherosclerosis; National Heart, Lung, and Blood Institute; National Institute of Child Health and Human Development; Nutritional Study; Obesity; Observational Study; Outcome; Outcome Measure; Phenols; Physical activity; Preparation; Procedures; Process; Program Sustainability; Protocols documentation; Psychometrics; Quality Control; Randomized, Controlled Trials; Research; Research Design; Research Personnel; Resources; Role; Sample Size; Services; Sleep; Specimen; Statistical Data Interpretation; Structure; System; Universities; Weight; Wood material; Youth; arm; cohort; college; cost effectiveness; data de-identification; data exchange; data harmonization; data management; data quality; demographics; design; digital assessment; executive function; experience; improved; member; obesity in children; obesity risk; pediatric department; preservation; programs; quality assurance; relational database; sound; synergism; vaccine efficacy

The Biostatistics and Data Management Core (BDM-Core) will provide data management and analysis support to the program projects. Its services will include statistical and study design guidance, protocol preparation assistance and evaluation, statistical analysis and interpretation of results, data management and quality assurance. Housed in the Children’s Nutrition Research Center, the BDM-Core is easily accessible to all Project leads. BDM-Core personnel will consist of PhD- and MS-level biostatisticians and a database manager. The Core will handle requests for secondary data analysis within the program, and submit de-identified data to the NICHD Data and Specimen Hub. To promote synergy and cost-effectiveness within the program, the BDM-Core will collaborate with the Digital Assessment Core to facilitate the structure and variable formats in TDM and accelerometer-derived data sets for use by all projects. Collaboration with the Administrative Core will occur by contributing to its educational outreach activities, DSMB support, and sharing of pertinent information in its Electronic Management System. Cost-effectiveness will be promoted by housing a database manager to build and maintain a central REDCap database for all projects, support for scientific programming, data harmonization, dissemination of scientific and technical knowledge, results discussion and interpretation across all projects, and activities to promote long-term sustainability. BDM-Core members have expertise in assessing obesity risk and executive functioning outcomes, with years of experience in several advanced areas, such as clinical trials, non- randomized observational studies, study design and sample size estimation, longitudinal data analysis, generalized linear mixed models, multilevel structural equation modeling, causal inference, missing data.

生物统计学和数据管理核心（BDM核）将提供数据管理和分析支持 它的服务将包括统计和研究设计指南，协议准备 协助和评估，统计分析和结果，数据管理和质量的解释 保证。 BDM核可容易地安置在儿童营养研究中心中 项目领导。 BDM核心人员将由博士学位和MS级生物统计学家和数据库经理组成。 核心将处理该程序中辅助数据分析的请求，并将被取消识别的数据提交给 NICHD数据和标本中心。 为了促进该计划中的协同作用和成本效益，BDM核心将与数字合作 评估核心，以促进TDM和加速度计衍生的数据集中的结构和可变格式 用于所有项目。与行政核心合作将通过为其教育做出贡献而发生 外展活动，DSMB支持以及其电子管理系统中相关信息的共享。 成本效益将通过容纳数据库经理来促进成本效益，以构建和维护中央redcap 所有项目的数据库，支持科学编程，数据协调，科学传播 以及所有项目的技术知识，结果讨论和解释以及促进的活动 长期可持续性。 BDM核心成员有评估肥胖风险和高管的专家 功能效果，在几个晚期领域拥有多年的经验，例如临床试验，非 - 随机观察研究，研究设计和样本量估计，纵向数据分析， 广义线性混合模型，多级结构方程建模，因果推断，缺少数据。