NICHD HUMAN BIOSPECIMEN REPOSITORY – MPIDB PHACS HOPE SPECIMEN

NICHD 人类生物样本存储库 — MPIDB PHACS HOPE 样本

• 批准号: 10701123
• 负责人: BRITTANY MARTIN
• 金额: $ 5.3万
• 依托单位: FISHER BIOSERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-23 至 2024-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10701123
• 关键词: 18 year old; Acquired Immunodeficiency Syndrome; Adolescent; Age; Bar Codes; Biological Specimen Banks; Cataloging; Child; Childhood; Clinical; Clinical Research; Cohort Studies; Communicable Diseases; Contracts; Data; Database Management Systems; Enrollment; Ensure; Equipment; Equipment and supply inventories; Exposure to; Family; Future; HIV; HIV-exposed uninfected infant; Health; Human; Human Resources; Individual; Infant; Monitor; National Institute of Child Health and Human Development; Online Systems; Outcome; Perinatal; Pregnancy; Protocols documentation; Regulation; Reproductive Health; Research; Research Activity; Sampling; Secure; Services; Shipping; Site; Specimen; Support System; System; Toxic effect; Tube; United States; Woman; Youth; base; computerized; experience; operation; pediatric human immunodeficiency virus; perinatal HIV; pregnant; programs; quality assurance; repository; reproductive; web-accessible; young woman

The Maternal and Pediatric Infectious Disease Branch (MPIDB) promotes research to investigate the impact and treatment of HIV, its complications, and other significant infectious diseases in infants, children, adolescents, and pregnant and nonpregnant women. This includes contracted clinical research activities conducted primarily in two major networks that actively collect specimens to be housed in the NICHD repository. These are the Pediatric HIV AIDS Cohort Study (PHACS). PHACS is a multicenter United States-based program that follows both perinatally HIV-infected youth and HIV-exposed/uninfected infants, children, and youth. PHACS currently includes four main protocols and four sub studies. A wide variety of specimen types are collected at 18 SMARTT (Surveillance Monitoring for ART Toxicities Study in HIV-uninfected Children Born to HIV-infected Women) and 14 AMP (Adolescent Master Protocol) current study sites that require repository services. The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) explores reproductive health choices, including pregnancy, and overall health outcomes, including reproductive health outcomes. HOPE provides the opportunity to inform future advancements for women living with HIV and their families.

母婴传染病处 (MPIDB) 促进研究艾滋病毒、其并发症以及其他重大传染病对婴儿、儿童、青少年以及孕妇和非孕妇的影响和治疗。这包括主要在两个主要网络中进行的合同临床研究活动，这些网络积极收集标本并存放在 NICHD 存储库中。这些是儿科 HIV 艾滋病队列研究 (PHACS)。 PHACS 是一项基于美国的多中心计划，跟踪围产期感染艾滋病毒的青少年以及暴露/未感染艾滋病毒的婴儿、儿童和青少年。 PHACS 目前包括四个主要方案和四个子研究。 18 个 SMARTT（对感染 HIV 的妇女所生的未感染 HIV 的儿童进行 ART 毒性研究的监测）和 14 个 AMP（青少年主方案）当前的研究地点收集了多种样本类型，需要储存库服务。 围绕怀孕和接触艾滋病毒/抗逆转录病毒药物的健康结果 (HOPE) 探讨了生殖健康选择（包括怀孕）和整体健康结果（包括生殖健康结果）。 HOPE 为感染艾滋病毒的女性及其家人提供了了解未来进步的机会。