Institutional Career Development Core

机构职业发展核心

• 批准号: 10674063
• 负责人: JEANINE M. GENKINGER
• 金额: $ 139.76万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674063
• 关键词: Acceleration; Benchmarking; Clinical; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Dentistry; Development; Discipline; Discipline of Nursing; Disease; Education; Effectiveness; Engineering; Entrepreneurship; Evaluation; Exposure to; Faculty; Funding; Goals; Grant; Health Professional; Individual; Institution; Interdisciplinary Study; K-Series Research Career Programs; Knowledge; Lead; Medical center; Medicine; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Methods; National Center for Advancing Translational Sciences; National Center for Research Resources; National Research Service Awards; Operative Surgical Procedures; Patients; Prevention; Program Development; Program Effectiveness; Psychiatry; Public Health; Research; Research Institute; Research Methodology; Research Personnel; Research Project Grants; Resources; Scholars Program; Schools; Science; Scientist; TNFSF15 gene; Teacher Professional Development; Training; Training Programs; Translating; Translational Research; Universities; Workforce Development; big-data science; career; career development; clinically relevant; curriculum development; design; effectiveness evaluation; implementation science; improved; innovation; member; multidisciplinary; next generation; novel; patient oriented research; precision medicine; prevent; professor; programs; recruit; skills; summer research

The goal for our proposed KL2 Mentored Career Development Award Program is to maintain excellence and mentorship program that imparts the skills essential to conduct clinical and translational science in the era of interdisciplinary team science, precision medicine (PM), big data, and implementation science. At Columbia University Irving Medical Center (CUIMC), the KL2 program operates across schools, departments, and divisions as the only institution- wide disease-agnostic career development program in clinical and translational research. The Irving Institute's translational workforce development (TWD) of clinician and non-clinician scientists is centered in TRANSFORM (TRaining And Nurturing Scholars For Research that is Multidisciplinary), which oversees the Institutional Career Development Core (KL2 Mentored Career Development Award Program). The goal is to recruit individuals who conduct cutting edge and clinically relevant research regardless of the disease focus. Recruitment will focus on investigators from diverse backgrounds with research or health professional doctorates in medicine, surgery, nursing, dentistry, public health, psychiatry, arts and sciences, and engineering. The KL2 program will promote career development, translational capabilities, and collaborative and entrepreneurial skills of junior faculty from diverse disciplines who have recently finished research or health professional doctoral training. KL2 graduates will receive excellent and extensive career mentoring, and gain expertise in advanced clinical and translational research methods and comprehensive experimental approaches. This mentoring and training will allow KL2 scholars to compete more effectively for external funding, enhance their effective participation in interdisciplinary teams, and contribute to prevention and treatment of diseases through clinical and translational research. Our KL2 graduates will also be able to pay forward these skills through training and mentorship of the next generation of scientists. As such, the Specific Aims are: Aim 1. To continue our successful and innovative KL2 career development program and develop new programs to enhance the ability of our KL2 scholars to engage in and lead interdisciplinary team science and translate new discoveries to benefit our patients and communities. Aim 2. To demonstrate the effectiveness of the KL2 program through continuous comprehensive and systematic evaluation and quality improvement using key metrics, including Common Metrics, to optimize the impact of our educational and workforce development programs. Aim 3. To accelerate the dissemination of our training approaches to our partners at Columbia University (CU), the regional tri-state consortium (TriCon) of Clinical and Translational Science Award (CTSA) Program hubs and network, and the clinical and translational while enhancing and innovating our successful junior faculty training field at large.

我们拟议的KL2指导职业发展奖计划的目标是保持卓越 和指导计划，该计划赋予在跨学科团队科学，精密医学（PM），大数据和实施科学时代进行临床和转化科学必不可少的技能。在哥伦比亚大学欧文医学中心（CUIMC），KL2计划跨学校，部门和部门运营，是唯一的机构 临床和转化研究方面的广泛疾病不足的职业发展计划。欧文 研究所的转化劳动力发展（TWD）是临床医生和非临床科学家的中心 转型（培训和培育研究学者，这是多学科的），它监督 机构职业发展核心（KL2指导了职业发展奖计划）。目标是 无论疾病如何 重点。招聘将专注于来自研究或卫生专业人员的不同背景的调查员 医学，手术，护理，牙科，公共卫生，精神病学，艺术与科学博士学位 工程。 KL2计划将促进职业发展，翻译能力和协作，并 来自不同学科的初级教师的创业技能，这些学科最近完成了研究或健康 专业博士培训。 KL2毕业生将获得出色而广泛的职业指导，并获得 高级临床和转化研究方法和全面的实验方法方面的专业知识。 这种指导和培训将使KL2学者能够更有效地竞争外部资金，增强 他们有效参与跨学科团队，并为预防和治疗疾病做出贡献 通过临床和转化研究。我们的KL2毕业生也将能够通过 下一代科学家的培训和指导。因此，具体目的是：目标1。继续 我们成功，创新的KL2职业发展计划，并制定了新计划，以增强 我们的KL2学者参与和领导跨学科团队科学并将新发现转化为 使我们的患者和社区受益。目标2。通过 使用关键指标，包括 通用指标，以优化我们的教育和劳动力发展计划的影响。目标3 加速我们对哥伦比亚大学（CU）合作伙伴的培训方法的传播 临床和转化科学奖（CTSA）计划中心和网络的三州联盟（Tricon）， 以及临床和翻译，同时增强和创新了我们成功的初级教师培训领域。

项目成果

The coeliac stomach: gastritis in patients with coeliac disease.

• DOI: 10.1111/apt.13249
• 发表时间: 2015-07
• 期刊: Alimentary pharmacology & therapeutics
• 影响因子: 7.6
• 作者: Lebwohl B;Green PH;Genta RM
• 通讯作者: Genta RM

In Reply: Spontaneous MAOI hypertensive reaction, not likely armodafinil - tranylcypromine interaction.

答复：自发性 MAOI 高血压反应，不太可能是阿莫达非尼 - 反苯环丙明相互作用。

• DOI: 10.1016/j.jns.2019.01.002
• 发表时间: 2019
• 期刊: Journal of the neurological sciences
• 影响因子: 4.4
• 作者: Kinslow,ConnorJ;Miller,ElizaC
• 通讯作者: Miller,ElizaC

Long-term outcomes of mesial temporal laser interstitial thermal therapy for drug-resistant epilepsy and subsequent surgery for seizure recurrence: a multi-centre cohort study.

颞内侧激光间质热疗治疗耐药性癫痫和随后手术治疗癫痫复发的长期结果：一项多中心队列研究。

• DOI: 10.1136/jnnp-2022-330979
• 发表时间: 2023
• 期刊: Journal of neurology, neurosurgery, and psychiatry
• 作者: Youngerman,BrettE;Banu,MateiA;Khan,Farhan;McKhann,GuyM;Schevon,CatherineA;Jagid,JonathanR;Cajigas,Iahn;Theodotou,ChristianB;Ko,Andrew;Buckley,Robert;Ojemann,JeffreyG;Miller,JohnW;Laxton,AdrianW;Couture,DanielE;Popli,
• 通讯作者: Popli,

Comparing survival of older ovarian cancer patients treated with neoadjuvant chemotherapy versus primary cytoreductive surgery: Reducing bias through machine learning.

比较接受新辅助化疗与初次细胞减灭术治疗的老年卵巢癌患者的生存率：通过机器学习减少偏差。

• DOI: 10.1016/j.ygyno.2024.03.016
• 发表时间: 2024
• 期刊: Gynecologic oncology
• 影响因子: 4.7
• 作者: Huang,Yongmei;Rauh-Hain,JAlejandro;McCoy,ThomasH;Hou,JuneY;Hillyer,Grace;Ferris,JenniferS;Hershman,Dawn;Wright,JasonD;Melamed,Alexander
• 通讯作者: Melamed,Alexander

Acute hypertensive crisis and severe headache after concurrent use of armodafinil and tranylcypromine: Case report and review of the literature.

同时使用阿莫达非尼和反苯环丙明后发生急性高血压危象和严重头痛：病例报告和文献综述。

• DOI: 10.1016/j.jns.2018.07.023
• 发表时间: 2018
• 期刊: Journal of the neurological sciences
• 影响因子: 4.4
• 作者: Kinslow,ConnorJ;Shapiro,StevenD;Grunebaum,MichaelF;Miller,ElizaC
• 通讯作者: Miller,ElizaC