Administrative Core

行政核心

• 批准号: 10666593
• 负责人: Jasjit Singh Ahluwalia
• 金额: $ 65.51万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10666593
• 关键词: ARHGEF5 gene; Address; Advisory Committees; Alcohols; Applications Grants; Biological; Centers of Research Excellence; Chronic Disease; Clinical; Communities; Complement; Development Plans; Doctor of Philosophy; Educational workshop; Effectiveness; Elements; Eligibility Determination; Ensure; Evaluation; Faculty; Funding; Future; Goals; Grant; Hospitals; Individual; Institution; International; Investments; K-Series Research Career Programs; Leadership; Link; Mentors; Minnesota; Monitor; Morbidity - disease rate; National Institute on Alcohol Abuse and Alcoholism; National Institute on Minority Health and Health Disparities; Nicotine Dependence; Physicians; Pilot Projects; Positioning Attribute; Postdoctoral Fellow; Prevalence; Principal Investigator; Psychologist; Research; Research Ethics; Research Personnel; Research Project Grants; Research Training; Resources; Rhode Island; Science; Scientist; Secondary to; Secure; Series; Services; Substance Use Disorder; Talents; Training; Underrepresented Populations; United States National Institutes of Health; Universities; Work; Writing; addiction; burden of illness; career; career development; chronic pain; cohort; design; disorder risk; ethnic minority; experience; health disparity; high risk population; improved; innovation; interest; member; minority disparity; minority health; minority health disparity; mortality; multidisciplinary; opioid use disorder; organizational structure; programs; racial minority; recruit; senior faculty; substance use; success

Abstract The Center for Addiction and Disease Risk Exacerbation (CADRE) Administrative Core will provide the scientific leadership and administrative support to ensure the success of all components of this COBRE proposal. We will leverage the full enterprise of Brown University, affiliated academic hospitals, respective research centers, and the broader community in Providence, Rhode Island and beyond. The five specific aims are Specific Aim 1 – To establish a team and organizational structure to provide leadership and administrative support for scientific excellence and facilitating the goals of the CADRE. Specific Aim 2 – To provide state-of- the-art mentoring support and initiatives for the COBRE project leaders and pilot grant recipients with the goal of facilitating their success in achieving independent level grant funding. Specific Aim 3 - To develop, administer and continuously evaluate a pilot grants program. Specific Aim 4 – Increase the diversity of the biomedical workforce and research that addresses the health disparities found in the disproportionate prevalence of SUD, and the resultant increased morbidity and mortality among racial and ethnic minorities. Specific Aim 5 – To conduct ongoing evaluation of the overall CADRE effort, the committees, the cores and the research projects so that CADRE is continuously evolving and improving. We will have the support of a fully engaged eight-member Internal Advisory Committee, four of whom are current COBRE PI's, an External Advisory Committee that will have disciplinary depth and breadth, and the support of 12 senior faculty members at Brown and its affiliated hospitals who will be CADRE affiliated scientists. We have a number of innovative elements to our proposal. Our choice of Principal Investigator and Deputy Director were intentional, as both have complementary, yet different experience in research, training, and mentoring. Dr. Monti is a clinical psychologist who has been at Brown for decades, directs the Center for Alcohol and Addiction Studies (CAAS) at Brown, and is PI of a current P01. Dr. Ahluwalia is new to Brown, is a physician scientist, and was PI of a NIMHD P60 Center of Excellence in Minority Health. Monti has served on the National Advisory Council for NIAAA, and Ahluwalia has for NIMHD. Finally, Brown University's commitment to supporting CADRE's goal of diversifying the biomedical workforce and addressing health disparities, will be supported by (1) a $100,000 a year pilot grants program that focuses on addressing the higher burden of illness related to substance use and chronic disease among racial and ethnic minorities, and (2) a Brown-funded postdoctoral position given to someone from a group underrepresented in biomedical sciences. With this significant NIH and institutional investment, we will be able to significantly extend our current work so that it is interdisciplinary, has a significant biological component, and will propel the careers of talented project leaders to independence, and begin the careers of a new cohort of junior faculty through the pilot projects program.

抽象的 成瘾与疾病风险加剧中心（干部）行政核心将提供 科学领导力和行政支持，以确保该毛病的所有组成部分的成功 提议。我们将利用布朗大学的全部企业，会员学术医院，亲戚 研究中心以及普罗维登斯，罗德岛及其他地区的更广泛的社区。五个特定目标 是特定的目标1 - 建立团队和组织结构以提供领导和行政 支持科学卓越，并促进干部的目标。特定目标2 - 提供 针对目标的工行项目领导者和试点赠款的武器心理支持和计划 促进他们在实现独立级别赠款资金方面的成功。特定目标3-开发， 管理并不断评估试点赠款计划。特定目标4 - 增加多样性 生物医学劳动力和研究解决了不成比例的健康差异 SUD的患病率，以及随之而来的种族和少数民族的发病率和死亡率增加。 具体目标5 - 对整个干部工作，委员会，核心和核心进行持续评估 研究项目使干部正在不断发展和改善。我们将得到一个 完全由八人组成的内部咨询委员会，其中四个是当前的Cobre Pi，一个外部 咨询委员会将具有纪律深度和广度，并得到12名高级教师的支持 布朗及其会员医院的成员将成为干部会员科学家。我们有很多 我们提出的创新元素。我们选择的首席调查员和副主任是故意的， 由于两者都有完整的研究，培训和心理经验。蒙蒂博士是 临床心理学家几十年来一直在布朗，指导酒精与成瘾研究中心 （CAAS）在棕色，是当前P01的PI。 Ahluwalia博士是布朗的新手，是一位物理科学家，是 NIMHD p60少数民族健康卓越中心的PI。蒙蒂曾在国家咨询委员会任职 对于NIAAA，Ahluwalia为Nimhd提供了。最后，布朗大学致力于支持干部的目标 多元化生物医学劳动力和解决健康分配的多样化，将得到（1）100,000美元的支持 一年的飞行员赠款计划，重点是解决与药物使用相关的疾病的更高烧伤 种族和少数民族之间的慢性病，​​以及（2）棕色资助的博士后职位 来自生物医学科学的人数不足的人。有了这一重要的NIH和机构 投资，我们将能够大大扩展当前的工作，以使其跨学科，具有 重要的生物学组成部分，并将推动才华横溢的项目领导者的职业发展独立，并 通过试点项目计划开始新的初级教师的职业。