Core 3: Biostatistics, Bioinformatics & Data Management Core

核心3：生物统计学、生物信息学

基本信息

批准号：
10225549
负责人：
GANG LI
金额：
$ 19.58万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-11 至 2022-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10225549
关键词：
Applications Grants Area Bioinformatics Biological Sciences Biometry Biostatistics Core Brain Cellular biology Collaborations Comprehensive Cancer Center Computer software Data Data Analyses Databases Development Developmental Biology Developmental Cell Biology Environment Faculty Fostering Gene Expression Goals Individual Infrastructure Institutes Internet Leadership Malignant neoplasm of brain Manuscripts Methodology Molecular Molecular Biology Preparation Quality Control Recording of previous events Research Research Design Research Methodology Research Personnel Research Project Grants Resource Sharing Review Committee Statistical Data Interpretation Study Section Tissue Microarray Translational Research United States National Institutes of Health Variant Work anticancer research base biomathematics bisulfite sequencing career clinical trial analysis data management data repository data sharing design experience genomic data high dimensionality high throughput technology innovation member next generation sequencing programs success transcriptome sequencing

项目摘要

Core 3: Biostatistics, Bioinformatics & Data Management (BBD) SUMMARY/ABSTRACT The overall goal of Core 3, the Biostatistics, Bioinformatics and Data Management (BBD) Core, is to provide comprehensive support in the areas of biostatistics, bioinformatics, and data management for all research Projects, Developmental Research and Career Enhancement programs, and Cores in the UCLA SPORE in Brain Cancer. The BBD Core is comprised of multiple faculty members from the departments of Biostatistics, Biomathematics, Molecular, Cell, & Developmental Biology (MCDB), and the UCLA Institute of Quantitative & Computational Biosciences (QCB), as well as staff statisticians, database managers, bioinformaticians, database and applications development programmers, and web designers. Faculty members include nationally respected biostatisticians and bioinformaticians with broad expertise in general biostatistics, design and analysis of clinical trials, analysis and interpretation of high-dimensional tissue arrays and gene expression data, and next generation sequencing (NGS) data analysis and management, which are needed by the SPORE research projects. Collectively and individually, the members have participated in hundreds of studies involving diverse aspects of cancer research, especially translational research. They have experience working in large centers and have served on multiple NIH study sections and review committees. The Core’s biostatistics/bioinformatics faculty and staff are actively involved in UCLA Jonsson Comprehensive Cancer Center (JCCC) current projects and have an established a history of productive collaborations with many researchers in this proposed SPORE. The BBD Core works closely with the UCLA SPORE in Brain Cancer investigators to provide input on study design, statistical analysis plans, bioinformatics, data management issues.

核心 3：生物统计学、生物信息学和数据管理 (BBD) 摘要/摘要核心 3（生物统计学、生物信息学和数据管理 (BBD) 核心）的总体目标是提供为所有研究提供生物统计学、生物信息学和数据管理领域的全面支持加州大学洛杉矶分校 SPORE 的项目、发展研究和职业提升计划以及核心课程 BBD 核心由来自生物统计学、生物数学、分子、细胞和发育生物学 (MCDB) 以及加州大学洛杉矶分校定量与发育研究所计算生物科学 (QCB) 以及统计员、数据库管理员、生物信息学家、数据库和应用程序开发程序员以及网页设计师包括来自全国各地的人员。受人尊敬的生物统计学家和生物信息学家，在一般生物统计学、设计和临床试验分析、高维组织阵列和基因表达的分析和解释数据，以及下一代测序（NGS）数据分析和管理，这是 SPORE 成员以集体和个人的方式参与了数百项研究。他们涉及癌症研究的各个方面，尤其是转化研究。在大型中心工作，并曾在多个 NIH 研究部门和审查委员会任职。生物统计学/生物信息学教职员工积极参与加州大学洛杉矶分校琼森综合癌症研究中心（JCCC）当前的项目，并与许多人建立了富有成效的合作历史 BBD 核心与加州大学洛杉矶分校 SPORE 在脑癌领域密切合作。研究人员就研究设计、统计分析计划、生物信息学、数据管理提供意见问题。