Core 3: Biostatistics, Bioinformatics & Data Management Core

核心3：生物统计学、生物信息学

基本信息

批准号：
9983046
负责人：
GANG LI
金额：
$ 19.27万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-11 至 2022-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9983046
关键词：
Applications Grants Area Bioinformatics Biological Sciences Biometry Biostatistics Core Brain Cellular biology Collaborations Comprehensive Cancer Center Computer software Data Data Analyses Databases Development Developmental Biology Developmental Cell Biology Environment Faculty Fostering Gene Expression Goals Individual Infrastructure Institutes Internet Leadership Malignant neoplasm of brain Manuscripts Methodology Molecular Molecular Biology Preparation Quality Control Recording of previous events Research Research Design Research Methodology Research Personnel Research Project Grants Resource Sharing Review Committee Statistical Data Interpretation Study Section Tissue Microarray Translational Research United States National Institutes of Health Variant Work anticancer research base biomathematics bisulfite sequencing career clinical trial analysis data management data sharing data warehouse design experience genomic data high dimensionality high throughput technology innovation member next generation sequencing programs success transcriptome sequencing

项目摘要

Core 3: Biostatistics, Bioinformatics & Data Management (BBD) SUMMARY/ABSTRACT The overall goal of Core 3, the Biostatistics, Bioinformatics and Data Management (BBD) Core, is to provide comprehensive support in the areas of biostatistics, bioinformatics, and data management for all research Projects, Developmental Research and Career Enhancement programs, and Cores in the UCLA SPORE in Brain Cancer. The BBD Core is comprised of multiple faculty members from the departments of Biostatistics, Biomathematics, Molecular, Cell, & Developmental Biology (MCDB), and the UCLA Institute of Quantitative & Computational Biosciences (QCB), as well as staff statisticians, database managers, bioinformaticians, database and applications development programmers, and web designers. Faculty members include nationally respected biostatisticians and bioinformaticians with broad expertise in general biostatistics, design and analysis of clinical trials, analysis and interpretation of high-dimensional tissue arrays and gene expression data, and next generation sequencing (NGS) data analysis and management, which are needed by the SPORE research projects. Collectively and individually, the members have participated in hundreds of studies involving diverse aspects of cancer research, especially translational research. They have experience working in large centers and have served on multiple NIH study sections and review committees. The Core’s biostatistics/bioinformatics faculty and staff are actively involved in UCLA Jonsson Comprehensive Cancer Center (JCCC) current projects and have an established a history of productive collaborations with many researchers in this proposed SPORE. The BBD Core works closely with the UCLA SPORE in Brain Cancer investigators to provide input on study design, statistical analysis plans, bioinformatics, data management issues.

核心3：生物统计学，生物信息学与数据管理（BBD）摘要/摘要核心3的总体目标，生物统计学，生物信息学和数据管理（BBD）核心是为了提供所有研究的生物统计学，生物信息学和数据管理领域的全面支持项目，发展研究和职业增强计划以及UCLA孢子中的核心脑癌。 BBD核心由生物统计学部门的多个教职员工组成，生物学，分子，细胞和发育生物学（MCDB）和UCLA定量研究所计算生物科学（QCB）以及员工统计学家，数据库经理，生物信息学家，数据库和应用程序开发程序员以及网页设计师。教师包括全国尊敬的生物统计学家和生物信息学家在一般生物统计学，设计和分析临床试验，高维组织阵列和基因表达的分析和解释数据以及下一代测序（NGS）数据分析和管理，这是需要的孢子研究项目。成员们共同和单独参加了数百项研究涉及癌症研究的不同方面，特别是翻译研究。他们有工作经验在大型中心，曾在多个NIH研究部分和审查委员会中任职。核心的生物统计学/生物信息学教师和教职员工积极参与加州大学洛杉矶分校综合癌症中心（JCCC）当前项目，并与许多人建立了产品合作的历史该提议的孢子中的研究人员。 BBD核心与脑癌中的UCLA孢子紧密合作研究人员提供有关研究设计，统计分析计划，生物信息学，数据管理的意见问题。