Integrated Program in Endocrinology Translational Postdoctoral Training Program

内分泌学综合项目转化博士后培训项目

• 批准号: 10390410
• 负责人: IAN M. BIRD
• 金额: $ 32.91万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10390410
• 关键词: Endocrinology; Training Programs; post-doctoral training; programs

Abstract. The rate of progress in understanding the basis for reproductive health and disease is breathtaking, accelerated ever further by constant advances in cellular and molecular techniques. Nonetheless, research in traditional academic departments and research in clinical departments often does not overlap. As such, the PhD trained in a purely academic environment will remain unexposed to the clinical mindset and practices and so fail to pursue translational goals, while the clinician Fellow is well aware of the clinical problem and by definition focused on the human itself, but may be less aware of recent conceptual and methodologic advances available to investigate clinically derived research questions. As PA-18-403 RFA states, “past studies have shown that health professional trainees who train in programs with postdoctoral researchers who have intensive research backgrounds are more likely to apply for and receive subsequent research grant support”. To that end, the goal of this proposal is simple - to provide for the PhD and MD Fellow a combined and integrated immersion experience in a cutting edge cross campus research program that is in itself embedded in and focused upon a more clinical environment where health and disease is the primary consideration, and to then promote the use of nonhuman primate and human derived models in MD or PhD Fellowship projects lead by MD/DVM/PhD Faculty of combined clinical and traditional training backgrounds. The campus home for this program will be the integrated Program in Endocrinology (iPEnd), which was founded in 2016 to foster and promote collaboration focused on fetal development and the compromised adult outcomes of adverse pregnancy. We propose here that iPEnd also offers a vibrant interdisciplinary and multidisciplinary environment comprised of MD, PhD and DVM trained faculty with which both MD and PhD Postdoctoral Fellows could train together to enter the world of translational research. Such a blended training environment is very much needed if we are to maintain a future pool of interdisciplinary translational research team members intellectually and professionally ready to pursue the goals of NICHD to improve reproductive health and outcomes. Another consideration by NIH is that trainees do not go on to future independent success by simple exposure to ‘good science’ alone. Indeed, both Trainees and Trainers need support and professional education to ensure the best outcomes. To that end, our proposed training includes a deep immersion in higher level research training typical of many T32 programs at this time, but we aim to go far beyond to include the evidence based 8 core competencies for Postdoctoral trainees combined with added Mentee and Mentor training and the complimentary Professional Development Resources in order to achieve the rich blended training environment so strongly recommended by NIH. We believe iPEnd is ready to promote the concepts of the interdisciplinary and multidisciplinary ‘Translational Workforce’ through the proposed Training Program, operating within first class campus environment geared for basic but increasingly supportive of translational research. On that basis, we submit this application.

摘要。 通过细胞和分子技术的发展进步，加速了进一步的加速。 传统的学术部门和临床部门的研究通常不会重叠。 在纯粹的学术环境中接受培训将仍然未受临床心态，因此失败 追求翻译目标，虽然临床医生很清楚临床问题和定义 专注于人类的ISELF，但可能不太了解最近可用的概念和方法论 为了调查临床衍生的研究问题。 与有密集研究的博士后研究人员一起培训计划的卫生专业学员 背景很可能申请并获得随后的研究赠款支持。”为此，目标是目标 该提议的简单 - 为博士和MD研究员提供了合并和综合的沉浸式 在尖端跨校园校园研究计划中的经验，该计划嵌入并集中在 更多的临床环境和疾病是主要的考虑，并促进使用 由MD/DVM/PHD领导的MD或PHD奖学金项目中的非人类灵长类动物和人类衍生的模型 联合临床和传统培训背景的教师将是该计划的校园 内分泌学集成计划（IPEND）成立于2016年，旨在促进和促进协作 我们在这里提出的是胎儿发育和不良怀孕的成年人 该iPend还提供了由MD，PhD和和和 DVM训练有素的教师与医学博士和博士博士后研究员可以一起训练进入世界 翻译研究。 跨学科的翻译研究团队成员知识分子和专业准备追求 NICHD的健康状况不佳和成果。 确实，只要简单地接触“良好科学”，就可以继续取得独立的成功 培训师需要支持和专业教育，以达到最佳成果。 培训包括此时许多T32计划的典型的高级研究培训的深层沉浸式培训， 但是，我们的目标是超越包括证据的8个核心竞争能力 结合增加的导师培训和编译专业发展资源 为了实现NIH强烈推荐的丰富的混合培训环境 已准备好通过跨学科和多学科的“翻译员工”的概念 支撑培训计划，在一流的校园环境中运行 在此基础上，我们越来越支持翻译研究。