Development Research Program

发展研究计划

• 批准号: 10208811
• 负责人: ELIZABETH A GRIMM
• 金额: $ 8.94万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10208811
• 关键词: Authorization documentation; Award; Bioinformatics; Biology; Biometry; Budgets; Clinical; Clinical Research; Collaborations; Cutaneous Melanoma; Data; Data Analyses; Development; Environment; Evaluation; Faculty; Funding; Funding Agency; Future; Grant; Guidelines; Immune response; Immunotherapy; Incidence; Laboratories; Medical center; Methods; Minority; Monitor; Morbidity - disease rate; Outcome; Patient-Focused Outcomes; Patients; Peer Review; Philanthropic Fund; Pilot Projects; Postdoctoral Fellow; Prevention; Program Research Project Grants; Research; Research Design; Research Personnel; Research Project Grants; Resources; Role; Sampling; Scientist; Site; Societies; Testing; Texas; Tissues; University of Texas M D Anderson Cancer Center; Uveal Melanoma; Woman; base; design; feasibility testing; flexibility; follow-up; high reward; high risk; innovation; interest; melanoma; novel; parent grant; programs; research and development

Developmental Research Program: Project Summary/Abstract This SPORE in Melanoma Developmental Research Program (DRP) serves to identify and fund pilot projects that take maximum advantage of new research breakthroughs and novel ideas that may eventually reduce the incidence and morbidity or increase the survival of patients with melanoma. Progress in understanding of melanoma biology and the role of immune response in melanoma patient outcomes has led to substantial advances in both targeted and immunotherapies for melanoma patients, and much promise is held for immediate future advances. Therefore, we are particularly interested in leveraging novel ideas from investigators with a variety of expertise in this DRP, and providing seed money for testing creative hypotheses and obtaining preliminary data for projects that are not supported by current or alternative funding sources. High risk/high reward pilot projects are especially prioritized, and applications from women and minority or underserved investigators are strongly encouraged. The available DRP funds include the required $50,000 annually throughout the duration of the SPORE award, as well as an annual contribution of up to $100,000 from institutional “matching funds,” for a total of $150,000 per year. Applications for SPORE DRPs are solicited annually, with an aim to fund at least 3 one-year awards of up to $50,000 each, with the possibility of ongoing support for a second year award of $50,000 if requested and approved based on acceptable progress. Philanthropic funds will also be utilized if available to support high quality proposals. Projects that provide a “pipeline” of additional value to the main SPORE projects or that support other new or concurrent melanoma grants are welcomed.

发展研究计划：项目摘要/摘要 黑色素瘤发育研究计划（DRP）中的孢子旨在识别和资助试点项目 这最大程度地利用了新的研究突破和新颖的想法，最终可能会降低 发病率和发病率或增加黑色素瘤患者的存活率。 黑色素瘤生物学和免疫反应在黑色素瘤患者结局中的作用已导致大量 针对黑色素瘤患者的靶向和免疫疗法的进展，以及对 因此，未来的进步。 在此DRP中拥有各种专业知识的调查员，并主管种子资金来检验创意假设 并为当前或替代资金来源不支持的项目获得初步数据。 高风险/高风险/高奖励试点项目特别优先，妇女和少数民族的申请或 强烈鼓励服务不足的调查员。 每年获得孢子奖的期限，每年收缩高达100,000美元 从机构“匹配资金”中，每年总计$ 150,000。 每年，目的是至少以3年的3年奖励，最高可达50,000美元，并有可能持续 如果要求并根据可接受的进度获得批准，则支持50,000美元的Aear堡奖。 如果可以支持高质量，慈善资金也将被征收。 对主要孢子项目或支持其他新的或并发黑色素瘤的额外价值的“管道” 格兰斯受到欢迎。